Papaverine, an opium alkaloid influences hepatic and pulmonary glutathione s-transferase activity and glutathione content in rats View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-06

AUTHORS

Ritu Aneja, Archana Sharma, Anita Talwar, Sujata K. Dass, Ramesh Chandra

ABSTRACT

The present study evaluates the effect of oral administration of papaverine at differential dosing regimens (100 mg/kg bw and 200 mg/kg bw) on the hepatic and pulmonary glutathione S-transferase (GST) activity and glutathione content (GSH) in male Wistar rats. Papaverine treatment caused a pronounced increase in GST activity and GSH content at the higher dosing level in the rat liver and lung. We conclude that papaverine, can possibly act as a chemopreventive agent against chemical carcinogenesis. More... »

PAGES

107-110

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf03190584

DOI

http://dx.doi.org/10.1007/bf03190584

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1013664640

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15230338


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