Endovascular brachytherapy — Treatment planning and radiation protection View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1998-09

AUTHORS

Ulrich Quast, Dirk Flühs, Markus Bambynek

ABSTRACT

The risk of restenosis, main late effect limiting the success of percutaneous transluminal coronary artery angioplasty, can be reduced significantly by vascular radiotherapy, subsequent to PTCA. This discovery lead to the development of new irradiation techniques. Endovascular brachytherapy is the choice in treatment of coronary artery stenosis. Successful irradiation, however, requires precise treatment planning. This review addresses the physical possibilities and problems of intravascular brachytherapy planning, and the radiobiologically based definition of the target volume and of structures at risk. Recommendations for dose specification, recording and reporting are given. The criteria for selecting a vascular radiotherapy technique are discussed as well as the possibilities of dosimetric treatment planning and quality assurance based on precise plastic scintillator dosimetry and intravascular ultrasound. Radiation protection and safety must be reconsidered prior to the usage of therapeutic radiation sources in the catheter laboratory and for the decision about emergency plans. Finally, the design of clinical trials, the role of medical physicists, and the future of irradiation treatment of stenosis is discussed. More... »

PAGES

337-346

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf03043598

DOI

http://dx.doi.org/10.1007/bf03043598

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1031765683

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/9816519


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