Proton therapy for tumors of the skull base View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1999-06

AUTHORS

John E. Munzenrider, Norbert J. Liebsch

ABSTRACT

Charged particle beams are ideal for treating skull base and cervical spine tumors: dose can be focused in the target, while achieving significant sparing of the brain, brain stem, cervical cord, and optic nerves and chiasm. For skull base tumors, 10-year local control rates with combined proton-photon therapy are highest for chondrosarcomas, intermediate for male chordomas, and lowest for female chordomas (94%, 65%, and 42%, respectively). For cervical spine tumors, 10-year local control rates are not significantly different for chordomas and chondrosarcomas (54% and 48%, respectively), nor is there any difference in local control between males and females. Observed treatment-related morbidity has been judged acceptable, in view of the major morbidity and mortality which accompany uncontrolled tumor growth. More... »

PAGES

57-63

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf03038890

DOI

http://dx.doi.org/10.1007/bf03038890

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1032828853

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/10394399


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