Cancer du testicule: BEP et spermatogenèse View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2002-09

AUTHORS

Myriam Daudin, Eric Huyghe, Christine Chevreau, Michel Soulié, Louis Bujan

ABSTRACT

Les caractéristiques spermatiques de 44 hommes traités avec 2 cycles ou plus de chimiothérapie de type BEP pour des tumeurs testiculaires non séminomateuses ont été étudiées avant et 25.2 (± 19.4) mois après la fin de la chimiothérapie. La récupération des valeurs initiales de numération survenait plus fréquemment un an après la fin du traitement. Cette récupération était liée à la fonction testiculaire avant traitement et au temps écoulé depuis la fin de la chimiothérapie; dans la première année suivant la fin du traitement, cette récupération était fonction du nombre de cycles de BEP. Notre étude est rassurante dans le long terme sur la toxicité du BEP sur la spermatogenèse. Toutefois, des études génétiques sont nécessaires concernant les effets possibles des traitements sur le matériel génétique spermatique durant cette phase de récupération. More... »

PAGES

277

Journal

TITLE

Andrologia

ISSUE

3

VOLUME

12

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf03035140

DOI

http://dx.doi.org/10.1007/bf03035140

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1020422733


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