Environnement et Spermatogenèse View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2000-09

AUTHORS

L. Bujan

ABSTRACT

Plusieurs études récentes rapportent une altération de l’appareil reproducteur chez le mâle ainsi que des différences régionales suggérant un lien entre environnement et spermatogenèse. Les histoires du dibromochloropopane, du distilbène, du gossypol, démontrent l’influence d’une exposition professionnelle, médicamenteuse ou d’un mode de vie sur l’appareil reproducteur. Dans cette revue sont envisagés les facteurs chimiques (pesticides, métaux, solvants ...) physiques (radiations ionisantes, non ionisantes, chaleur), et les éléments du mode de vie (chaleur, position, habillement, alcool, tabac, stress, sport, alimentation) pouvant avoir une action délétère sur la spermatogenèse. L’hypothèse des perturbateurs endocriniens est discutée à la lumière d’études récentes faisant état de différences régionales. Les liens entre environement et spermatogenèse posent la question du type d’études à mener et celle des outils à utiliser. Si des études pluridisciplinaires sont encore nécessaires afin de précisément déterminer le rôle de ces facteurs dans la décroissance séculaire et les variations régionales de la spermatogenèse, il est suggéré que le sperme puisse être un indicateur de santé publique et que le principe de précaution soit institué et se traduise concrètement: 1) par une réelle action de prévention en milieu professionnel, 2) par l’évitement d’un facteur de risque découvert lors des consultations pour infécondité, 3) par la non-utilisation de substances n’ayant pas fait la preuve de leur innocuité dans les études toxicologiques chez l’animal. Par ailleurs, la mise en place d’une spermovigilance pourrait être souhaitable. More... »

PAGES

254-270

Journal

TITLE

Andrologia

ISSUE

3

VOLUME

10

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf03034746

DOI

http://dx.doi.org/10.1007/bf03034746

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1050246228


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125 schema:description Plusieurs études récentes rapportent une altération de l’appareil reproducteur chez le mâle ainsi que des différences régionales suggérant un lien entre environnement et spermatogenèse. Les histoires du dibromochloropopane, du distilbène, du gossypol, démontrent l’influence d’une exposition professionnelle, médicamenteuse ou d’un mode de vie sur l’appareil reproducteur. Dans cette revue sont envisagés les facteurs chimiques (pesticides, métaux, solvants ...) physiques (radiations ionisantes, non ionisantes, chaleur), et les éléments du mode de vie (chaleur, position, habillement, alcool, tabac, stress, sport, alimentation) pouvant avoir une action délétère sur la spermatogenèse. L’hypothèse des perturbateurs endocriniens est discutée à la lumière d’études récentes faisant état de différences régionales. Les liens entre environement et spermatogenèse posent la question du type d’études à mener et celle des outils à utiliser. Si des études pluridisciplinaires sont encore nécessaires afin de précisément déterminer le rôle de ces facteurs dans la décroissance séculaire et les variations régionales de la spermatogenèse, il est suggéré que le sperme puisse être un indicateur de santé publique et que le principe de précaution soit institué et se traduise concrètement: 1) par une réelle action de prévention en milieu professionnel, 2) par l’évitement d’un facteur de risque découvert lors des consultations pour infécondité, 3) par la non-utilisation de substances n’ayant pas fait la preuve de leur innocuité dans les études toxicologiques chez l’animal. Par ailleurs, la mise en place d’une spermovigilance pourrait être souhaitable.
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