Circadian rhythms of adenosine deaminase activity in human erythrocytes: A transverse study on young, elderly and senile demented subjects View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1985-10

AUTHORS

Germaine Cornélissen, Yvan Touitou, George Tritsch, André Bogdan, André Auzéby, Alain Reinberg, Franz Halberg

ABSTRACT

Adenosine deaminase activity (ADA) was determined around the clock in human plasma from different groups of subjects: presumably clinically healthy women in Minneapolis, USA; healthy medical students, healthy elderly men and women, and mentally will patients in Paris, France. In addition to analyses of variance, circadian characteristics were estimated individually and summarized by population-mean cosinor for each group. Technical and sampling considerations are documented: the individualized assessment of a circadian rhythm in adenosine deaminase is feasible in 8 out of 11 series from clinically healthy women covering 24h at 20-min intervals. A circadian population rhythm could be determined for the elderly men and women (p<0.05) and tentatively (p=0.053) for the senile demented patients. A difference in circadian group rhythm characteristics found between the healthy elderly subjects and patients with senile dementia deserves furhter exploration. More... »

PAGES

365-374

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf03029152

DOI

http://dx.doi.org/10.1007/bf03029152

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1079979021

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/3834580


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