Research on anesthesia, consciousness or both? Understanding our anesthetic drugs and defining the neural substrate View Full Text


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Article Info

DATE

2003-06

AUTHORS

Pierre Fiset

ABSTRACT

It is fundamental for our specialty to elucidate the mechanisms by which anesthetic drugs exert their action. It now seems that anesthesia is not the result of a generalized and non-specific action of drugs on the CNS, but occurs due to a complex action on cell membranes, specific ion channels and discrete parts of the CNS. The fact that we can induce discrete and dose-specific effects on attention, pain appreciation, memory, complex cognitive functions or consciousness itself suggests that our drugs act on specific parts of the CNS. From a broader perspective, it also means that we can use our clinical expertise to induce controlled modulation of cognitive functions in order to uncover their neural correlates. In the end, research on anesthetic mechanisms and consciousness are not dissociable because understanding our tools also helps to define the substrate. More... »

PAGES

r7-r11

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf03018148

DOI

http://dx.doi.org/10.1007/bf03018148

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1003455157


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