Influence du cycle menstruel sur le seuil de la douleur expérimentale View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-06

AUTHORS

M. Besson, V. Piguet, J. Desmeules, M. Kondo Oestreicher, R. Grandjean, F. Hermann, P. Dayer

ABSTRACT

Aimto assess the menstrual cycle impact on electrical pain threshold in female healthy volunteers.Methodsthe nociceptive flexion reflex (NFR) and the subjective pain threshold were recorded 3 times a week during a whole menstrual cycle in 23 healthy female volunteers, of whom 13 were taking an oral contraception and 10 not taking it.Resultssubjects without contraception tend to have lower mean values of NFR thresholds during the menstrual, follicular and luteal phases. During ovulation thresholds are significantly lower in the non-contraception group (32.53 [41.03-24.04] vs 25,99 [33,97-18.02] mAmp, p=0.04). Subjective thresholds also tend to be rated more unpleasant by the non-contraception group.ConclusionOur results are is agreement with previous trials in suggesting that the menstrual cycle may influence pain thresholds. Although numbers recruited were relatively small, this study underlines the importance of hormonal variations not only in moderating the transmission of nociceptive stimuli through the central nociceptive pathway but also on subjective integration of More... »

PAGES

73

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf03012811

DOI

http://dx.doi.org/10.1007/bf03012811

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1034450951


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