Symptomatic hyponatraemia due to inappropriate antidiuretic hormone secretion following minor surgery View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1991-03

AUTHORS

David Soroker, Tiberiu Ezri, Samuel Lurie, Steven Feld, Irena Savir

ABSTRACT

A rare case of the syndrome of inappropriate antidiuretic hormone secretion occurring after minor surgery is presented. A ten-year-old, previously healthy boy underwent general anaesthesia for detorsion and right orchiopexy. Throughout the operations, which lasted for one hour, he received 120 ml Ringer's lactate solution. The immediate postoperative period was uneventful. Twenty-two hours postoperatively he was found unconscious with generalized tonic-clonic seizures. Simultaneously obtained serum sodium concentration (121 mEq.L-1) serum osmolarity (265 mEq.L-1), urine sodium concentration (87 mEq.L-1) and urine osmolarity (525 mEq.L-1) suggested inappropriate antidiuretic hormone secretion which was confirmed by an elevated serum arginine-vasopressin (AVP) level of 14.5 pcg.ml-1 (normal 1-5 pcg.ml-1) measured by radioimmune assay. He was treated with a single iv dose of 30 mg furosemide and fluid restriction, which produced a gradual increase of his serum sodium concentration to normal within two days. He was well during the remainder of his hospitalization. More... »

PAGES

225-226

References to SciGraph publications

  • 1976-07. The osmoregulation of vasopressin in KIDNEY INTERNATIONAL
  • 1980. Influence of Anaesthesia on the Endocrine System in ENDOCRINOLOGY IN ANAESTHESIA AND SURGERY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf03008151

    DOI

    http://dx.doi.org/10.1007/bf03008151

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1048890874

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/2021994


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