Identification of antifungal compounds from the seed oil ofAzadirachta Indica View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1998-06

AUTHORS

T. R. Govindachari, G. Suresh, Geetha Gopalakrishnan, Balaganesan Banumathy, S. Masilamani

ABSTRACT

Evaluation of the activity of the cold expeller neem oil(Azadirachta indica A. Juss.) and the fractions derived through solvent partitioning, againstDrechslera oryzae, Fusarium oxysporum andAlternaria tenuis showed that the active antifungal fraction is a mixture of tetranortriterpenoids. Further, testing the triterpenoidal mixture derived from the 90% methanol (MeOH) extract of neem oil against 13 phytopathogenic fungi revealed that various species were inhibited to different degrees. Direct preparative High Performance Liquid Chromatography (HPLC) of the active fractions and subsequent bioassay of the semi-pure fractions indicated that the active fractions contained major compounds such as 6-deacetylnimbin, azadiradione, nimbin, salannin and epoxyazadiradione. Pure azadiradione, nimbin, salannin and epoxy-azadiradione did not have appreciable activity. However, when these terpenoids were mixed and bioassayed, they showed antifungal activity, indicating possible additive/synergistic effects. More... »

PAGES

109-116

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02980677

DOI

http://dx.doi.org/10.1007/bf02980677

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1050685985


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/07", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Agricultural and Veterinary Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0607", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Plant Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0703", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Crop and Pasture Production", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "familyName": "Govindachari", 
        "givenName": "T. R.", 
        "id": "sg:person.064424500.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.064424500.14"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Suresh", 
        "givenName": "G.", 
        "id": "sg:person.01112670513.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112670513.01"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Gopalakrishnan", 
        "givenName": "Geetha", 
        "id": "sg:person.01227117113.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01227117113.71"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Banumathy", 
        "givenName": "Balaganesan", 
        "id": "sg:person.014107703737.57", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014107703737.57"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Centre for Agrochemical Research, SPIC Science Foundation, 600 032, Madras, India", 
          "id": "http://www.grid.ac/institutes/None", 
          "name": [
            "Centre for Agrochemical Research, SPIC Science Foundation, 600 032, Madras, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Masilamani", 
        "givenName": "S.", 
        "id": "sg:person.01022420110.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022420110.22"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf02981477", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047115757", 
          "https://doi.org/10.1007/bf02981477"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-94-011-2118-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048359519", 
          "https://doi.org/10.1007/978-94-011-2118-7"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1998-06", 
    "datePublishedReg": "1998-06-01", 
    "description": "Evaluation of the activity of the cold expeller neem oil(Azadirachta indica A. Juss.) and the fractions derived through solvent partitioning, againstDrechslera oryzae, Fusarium oxysporum andAlternaria tenuis showed that the active antifungal fraction is a mixture of tetranortriterpenoids. Further, testing the triterpenoidal mixture derived from the 90% methanol (MeOH) extract of neem oil against 13 phytopathogenic fungi revealed that various species were inhibited to different degrees. Direct preparative High Performance Liquid Chromatography (HPLC) of the active fractions and subsequent bioassay of the semi-pure fractions indicated that the active fractions contained major compounds such as 6-deacetylnimbin, azadiradione, nimbin, salannin and epoxyazadiradione. Pure azadiradione, nimbin, salannin and epoxy-azadiradione did not have appreciable activity. However, when these terpenoids were mixed and bioassayed, they showed antifungal activity, indicating possible additive/synergistic effects.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/bf02980677", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1121015", 
        "issn": [
          "0334-2123", 
          "1876-7184"
        ], 
        "name": "Phytoparasitica", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "26"
      }
    ], 
    "keywords": [
      "high-performance liquid chromatography", 
      "preparative high-performance liquid chromatography", 
      "semi-pure fractions", 
      "performance liquid chromatography", 
      "active fraction", 
      "solvent partitioning", 
      "liquid chromatography", 
      "major compounds", 
      "appreciable activity", 
      "synergistic effect", 
      "antifungal activity", 
      "compounds", 
      "mixture", 
      "salannin", 
      "nimbin", 
      "antifungal compounds", 
      "chromatography", 
      "subsequent bioassay", 
      "neem oil", 
      "antifungal fraction", 
      "methanol extract", 
      "terpenoids", 
      "tetranortriterpenoids", 
      "phytopathogenic fungi", 
      "fraction", 
      "activity", 
      "oil", 
      "different degrees", 
      "epoxyazadiradione", 
      "bioassay", 
      "extract", 
      "species", 
      "partitioning", 
      "oryzae", 
      "effect", 
      "neem", 
      "fungi", 
      "degree", 
      "identification", 
      "indica", 
      "evaluation", 
      "azadiradione", 
      "tenuis"
    ], 
    "name": "Identification of antifungal compounds from the seed oil ofAzadirachta Indica", 
    "pagination": "109-116", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1050685985"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf02980677"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf02980677", 
      "https://app.dimensions.ai/details/publication/pub.1050685985"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-09-02T15:48", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_290.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/bf02980677"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf02980677'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf02980677'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf02980677'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf02980677'


 

This table displays all metadata directly associated to this object as RDF triples.

140 TRIPLES      21 PREDICATES      72 URIs      60 LITERALS      6 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf02980677 schema:about anzsrc-for:06
2 anzsrc-for:0607
3 anzsrc-for:07
4 anzsrc-for:0703
5 schema:author N507667ea399745d8b5eff4cfa0ca6ee0
6 schema:citation sg:pub.10.1007/978-94-011-2118-7
7 sg:pub.10.1007/bf02981477
8 schema:datePublished 1998-06
9 schema:datePublishedReg 1998-06-01
10 schema:description Evaluation of the activity of the cold expeller neem oil(Azadirachta indica A. Juss.) and the fractions derived through solvent partitioning, againstDrechslera oryzae, Fusarium oxysporum andAlternaria tenuis showed that the active antifungal fraction is a mixture of tetranortriterpenoids. Further, testing the triterpenoidal mixture derived from the 90% methanol (MeOH) extract of neem oil against 13 phytopathogenic fungi revealed that various species were inhibited to different degrees. Direct preparative High Performance Liquid Chromatography (HPLC) of the active fractions and subsequent bioassay of the semi-pure fractions indicated that the active fractions contained major compounds such as 6-deacetylnimbin, azadiradione, nimbin, salannin and epoxyazadiradione. Pure azadiradione, nimbin, salannin and epoxy-azadiradione did not have appreciable activity. However, when these terpenoids were mixed and bioassayed, they showed antifungal activity, indicating possible additive/synergistic effects.
11 schema:genre article
12 schema:isAccessibleForFree false
13 schema:isPartOf Nb81171b9145044caa430326c7a353dcf
14 Nf28f868ac5e149b1807b024a241cf665
15 sg:journal.1121015
16 schema:keywords active fraction
17 activity
18 antifungal activity
19 antifungal compounds
20 antifungal fraction
21 appreciable activity
22 azadiradione
23 bioassay
24 chromatography
25 compounds
26 degree
27 different degrees
28 effect
29 epoxyazadiradione
30 evaluation
31 extract
32 fraction
33 fungi
34 high-performance liquid chromatography
35 identification
36 indica
37 liquid chromatography
38 major compounds
39 methanol extract
40 mixture
41 neem
42 neem oil
43 nimbin
44 oil
45 oryzae
46 partitioning
47 performance liquid chromatography
48 phytopathogenic fungi
49 preparative high-performance liquid chromatography
50 salannin
51 semi-pure fractions
52 solvent partitioning
53 species
54 subsequent bioassay
55 synergistic effect
56 tenuis
57 terpenoids
58 tetranortriterpenoids
59 schema:name Identification of antifungal compounds from the seed oil ofAzadirachta Indica
60 schema:pagination 109-116
61 schema:productId N24f7c845dc4046c0b06f7374fd79b730
62 N8da0a3320dd147abb141f6c3d085af91
63 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050685985
64 https://doi.org/10.1007/bf02980677
65 schema:sdDatePublished 2022-09-02T15:48
66 schema:sdLicense https://scigraph.springernature.com/explorer/license/
67 schema:sdPublisher Nd1267858753a463cbde9d1a22f9c9679
68 schema:url https://doi.org/10.1007/bf02980677
69 sgo:license sg:explorer/license/
70 sgo:sdDataset articles
71 rdf:type schema:ScholarlyArticle
72 N1b287ca515f04af686313ee2498ad2eb rdf:first sg:person.014107703737.57
73 rdf:rest Nf702ca5fa0de417c8517be4d8205f08e
74 N24f7c845dc4046c0b06f7374fd79b730 schema:name dimensions_id
75 schema:value pub.1050685985
76 rdf:type schema:PropertyValue
77 N34747840b38a4f8e98acb06e362f65f7 rdf:first sg:person.01112670513.01
78 rdf:rest N6ddf757dd2c94a1d9441682e6a756882
79 N507667ea399745d8b5eff4cfa0ca6ee0 rdf:first sg:person.064424500.14
80 rdf:rest N34747840b38a4f8e98acb06e362f65f7
81 N6ddf757dd2c94a1d9441682e6a756882 rdf:first sg:person.01227117113.71
82 rdf:rest N1b287ca515f04af686313ee2498ad2eb
83 N8da0a3320dd147abb141f6c3d085af91 schema:name doi
84 schema:value 10.1007/bf02980677
85 rdf:type schema:PropertyValue
86 Nb81171b9145044caa430326c7a353dcf schema:volumeNumber 26
87 rdf:type schema:PublicationVolume
88 Nd1267858753a463cbde9d1a22f9c9679 schema:name Springer Nature - SN SciGraph project
89 rdf:type schema:Organization
90 Nf28f868ac5e149b1807b024a241cf665 schema:issueNumber 2
91 rdf:type schema:PublicationIssue
92 Nf702ca5fa0de417c8517be4d8205f08e rdf:first sg:person.01022420110.22
93 rdf:rest rdf:nil
94 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
95 schema:name Biological Sciences
96 rdf:type schema:DefinedTerm
97 anzsrc-for:0607 schema:inDefinedTermSet anzsrc-for:
98 schema:name Plant Biology
99 rdf:type schema:DefinedTerm
100 anzsrc-for:07 schema:inDefinedTermSet anzsrc-for:
101 schema:name Agricultural and Veterinary Sciences
102 rdf:type schema:DefinedTerm
103 anzsrc-for:0703 schema:inDefinedTermSet anzsrc-for:
104 schema:name Crop and Pasture Production
105 rdf:type schema:DefinedTerm
106 sg:journal.1121015 schema:issn 0334-2123
107 1876-7184
108 schema:name Phytoparasitica
109 schema:publisher Springer Nature
110 rdf:type schema:Periodical
111 sg:person.01022420110.22 schema:affiliation grid-institutes:None
112 schema:familyName Masilamani
113 schema:givenName S.
114 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022420110.22
115 rdf:type schema:Person
116 sg:person.01112670513.01 schema:familyName Suresh
117 schema:givenName G.
118 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112670513.01
119 rdf:type schema:Person
120 sg:person.01227117113.71 schema:familyName Gopalakrishnan
121 schema:givenName Geetha
122 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01227117113.71
123 rdf:type schema:Person
124 sg:person.014107703737.57 schema:familyName Banumathy
125 schema:givenName Balaganesan
126 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014107703737.57
127 rdf:type schema:Person
128 sg:person.064424500.14 schema:familyName Govindachari
129 schema:givenName T. R.
130 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.064424500.14
131 rdf:type schema:Person
132 sg:pub.10.1007/978-94-011-2118-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048359519
133 https://doi.org/10.1007/978-94-011-2118-7
134 rdf:type schema:CreativeWork
135 sg:pub.10.1007/bf02981477 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047115757
136 https://doi.org/10.1007/bf02981477
137 rdf:type schema:CreativeWork
138 grid-institutes:None schema:alternateName Centre for Agrochemical Research, SPIC Science Foundation, 600 032, Madras, India
139 schema:name Centre for Agrochemical Research, SPIC Science Foundation, 600 032, Madras, India
140 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...