Anti-platelet pentacyclic triterpenoids from leaves ofcampsis grandiflora View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-04

AUTHORS

Jing Ling Jin, Yong Yook Lee, Jung Eun Heo, Sanghyun Lee, Jeong Mi Kim, Hye Sook Yun-Choi

ABSTRACT

Five pentacyclic triterpenoids, oleanolic acid (1), hederagenin (2), ursolic acid (3), tormentic acid (4) and myrianthic acid (5), were isolated from the methanol extract of the leaves of Campsis grandiflora, and structures of the compounds were established by the spectroscopic methods. Compounds 2, 3, 4, and 5 were isolated for the first time from the genus Campsis. All of the compounds (IC50: 45.3, 32.8, 82.6, 42.9 and 46.2 microM respectively) were as equivalently inhibitive as acetylsalicylic acid (IC50: 57.0 microM) on epinephrine induced platelet aggregation. More... »

PAGES

376-380

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02980076

DOI

http://dx.doi.org/10.1007/bf02980076

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1046601904

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15180300


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