Cytotoxic constituents isolated from the fruit bodies ofHypsizigus marmoreus View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-01

AUTHORS

Ming-Lu Xu, Jae-Young Choi, Byeong-Seon Jeong, Gao Li, Kap-Rang Lee, Chong-Soon Lee, Mi-Hee Woo, Eung Seok Lee, Yurngdong Jahng, Hyeun-Wook Chang, Seung-Ho Lee, Jong-Keun Son

ABSTRACT

The bioactivity-guided fractionation of chloroform extracts of the fruit bodies of Hypsizigus marmoreus led to our isolation of (22E,24R)-ergosta-7,22-diene-3beta,5alpha,6beta-triol (1), ergosterol-3-O-beta-D-glucopyranoside (2), 5alpha,8alpha-epidioxyergosta-6,22-dien-3beta-ol (3), hypsiziprenol A9 (4), hypsiziprenol AA8 (5), hypsiziprenol AA9 (6) and hypsiziprenol BA10 (7). Among these seven isolates, compound 2 was identified for the first time from this plant. All compounds (1-7) exhibited moderate cytotoxicity towards cultured human colon carcinoma (HT-29), human breast carcinoma (MCF-7) and human hepatoblastoma (HepG-2) cell lines. More... »

PAGES

28-33

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02977775

DOI

http://dx.doi.org/10.1007/bf02977775

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1044415364

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17328239


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