Synthesis, cytotoxicity and structure-activity relationship study of terpyridines View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2006-12

AUTHORS

Long-Xuan Zhao, Jyoti Sherchan, Jung Ki Park, Yurngdong Jahng, Byeong-Seon Jeong, Tae Cheon Jeong, Chong-Soon Lee, Eung-Seok Lee

ABSTRACT

For the development of novel antitumor agents, we designed and synthesized terpyridines, and their biological activities were evaluated. Although most of the newly prepared terpyridines showed strong cytotoxicity against several human cancer cell lines, [2,2';6',2"]-terpyridine displayed the most significant cytotoxicity.

PAGES

1091-1095

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02969297

DOI

http://dx.doi.org/10.1007/bf02969297

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1030100289

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17225456


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