Ti Breast Cancer Associated with Von Recklinghausen’s Neurofibromatosis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1999-07

AUTHORS

Yoshihiko Murayama, Yutaka Yamamoto, Naoki Shimojima, Tetsuya Takahara, Kaichiro Kikuchi, Shuhei lida, Yasuko Kondo

ABSTRACT

A rare case of breast cancer associated with von Recklinghausen's neurofibromatosis is reported. This case and review of the literature illustrate the problems of clinical diagnosis.A 66-year-old woman who had undergone sigmoidectomy for sigmoid colon cancer two years previously, was admitted to the hospital because of a left breast skin retraction in October, 1998. The patient had von Recklinghausen's disease (neurofibromatosis type 1). The TNM clinical staging was TlcNOMO. Modified radical mastectomy was performed. The histopathological diagnosis of the breast tumor was invasive ductal carcinoma and the skin tumor was neurofibroma. The pTNM pathological staging was pTlcNlaMO.Among patients similar to our case, almost all were staged higher than T2. This may be because multiple neurofibromas obscure breast mass at palpation, leading to delayed detection of the cancer. Systemic and careful exploration is essential for patients with von Recklinghausen's neurofibromatosis to detect breast cancer at an early stage. More... »

PAGES

227-230

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02967173

DOI

http://dx.doi.org/10.1007/bf02967173

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1001107941

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18843552


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