The main immunogenic region (MIR) of the nicotinic acetylcholine receptor and the anti-MIR antibodies View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1991-03

AUTHORS

S. J. Tzartos, M. T. Cung, P. Demange, H. Loutrari, A. Mamalaki, M. Marraud, I. Papadouli, C. Sakarellos, V. Tsikaris

ABSTRACT

Myasthenia gravis (MG) is caused by autoantibodies against the nicotinic acetylcholine receptor (AChR) of the neuromuscular junction. The anti-AChR antibodies are heterogeneous. However, a small region on the extracellular part of the AChR alpha subunit, called the main immunogenic region (MIR), seems to be the major target of the anti-AChR antibodies, but not of the specific T-cells, in experimental animals and possibly in MG patients. The major loop of the overlapping epitopes for all testable anti-MIR monoclonal antibodies (MAbs) was localized within residues 67-76 (WNPADYGGIK for Torpedo and WNPDDYGGVK for human AChR) of the alpha subunit. The N-terminal half of alpha 67-76 is the most critical, Asn68 and Asp71 being indispensable for binding. Yet anti-MIR antibodies are functionally and structurally quite heterogeneous. Anti-MIR MAbs do not affect channel gating, but they are very potent in mediating acceleration of AChR degradation (antigenic modulation) in cell cultures and in transferring experimental MG in animals. Fab fragments of anti-MIR MAbs bound to the AChR prevent the majority of the MG patients' antibodies from binding to and causing loss of the AChR. Whether this inhibition means that most MG antibodies bind on the same small region or is a result of broad steric/allosteric effects is under current investigation. More... »

PAGES

1

References to SciGraph publications

  • 1985-06. Quaternary structure of the acetylcholine receptor in NATURE
  • 1986-02. Synthesis and assembly of acetylcholine receptor, a multisubunit membrane glycoprotein in THE JOURNAL OF MEMBRANE BIOLOGY
  • 1987-12. Molecular studies of the neuronal nicotinic acetylcholine receptor family in MOLECULAR NEUROBIOLOGY
  • 1990-11. Three-dimensional structure of an idiotope–anti-idiotope complex in NATURE
  • 1988-09. Binding and blocking antibodies to the human acetylcholine receptor: Are they selected in various myasthenia gravis forms? in IMMUNOLOGIC RESEARCH
  • 1980-05. Myasthenia gravis induced by monoclonal antibodies to acetylcholine receptors in NATURE
  • 1989. Use of Synthetic Peptides and High Affinity Protein Ligands for Structural Studies of Central and Peripheral Nicotinic Receptors in MOLECULAR BIOLOGY OF NEURORECEPTORS AND ION CHANNELS
  • 1991. Studying the Acetylcholine Receptor with Monoclonal Antibodies in CURRENT ASPECTS OF THE NEUROSCIENCES
  • 1988. Structure and Function of the Nicotinic Acetylcholine Receptor in THE CHOLINERGIC SYNAPSE
  • 1984-02. Expression of functional acetylcholine receptor from cloned cDNAs in NATURE
  • 1989. Fine Structural Characterization of the Main Immunogenic Region of the Nicotinic Acetylcholine Receptor in MOLECULAR BIOLOGY OF NEURORECEPTORS AND ION CHANNELS
  • 1988-03. Reshaping human antibodies for therapy in NATURE
  • 1987-06. Functional acetylcholine receptor in PC12 cells reacts with a monoclonal antibody to brain nicotinic receptors in NATURE
  • 1988-10. Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance in NATURE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf02935610

    DOI

    http://dx.doi.org/10.1007/bf02935610

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1015458745

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/1725702


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