Lactic acid production by pellet-formRhizopus oryzae in a submerged system View Full Text


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Article Info

DATE

1995-09

AUTHORS

C. W. Yang, Zhongjing Lu, George T. Tsao

ABSTRACT

Rhizopus oryzae NRRL 395 produces optically pureL(+)-lactic acid that is highly preferred for the production of environmentally benign polymers. With xylose as the carbon source for cultivation, it can be self-immobilized as pellets with a size of about 1mm. Repeated usage of the same pellets by transferring them into fresh media every time when the glucose was exhausted over a period of 22 d yielded 1742 or 2001 g/L lactic acid total (based on 100-mL working volume) depending on the media used. Lactic acid is known to be a strong inhibitor for both growth and production, and it can be removed continuously by the adsorption on the PVP resin. With the fermenter-adsorber system, the fermentation can be performed as effectively as the ones with added neutralizing agents, such as calcium carbonate and sodium hydroxide. One problem of the fermenter-adsorber system is that lower production was obtained than in shake flasks; hence, proper reactor design is necessary to improve the process. More... »

PAGES

57-71

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02933411

DOI

http://dx.doi.org/10.1007/bf02933411

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1020188085


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