Artificial gravity loading increases the effects of the glutamate transporter inhibitors on the glutamate release and uptake in rat brain ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2006-09

AUTHORS

Tatiana Borisova, Natalia Krisanova, Nina Himmelreich

ABSTRACT

The present study evaluated the effect of artificial gravity loading on transporter-mediated uptake and release of L-glutamate using the inhibitors of glutamate transporters as tools. The competitive nontransportable, DL-threo-beta-benzyloxyaspartate (DL-TBOA), and transportable, DL-threo-beta-hydroxyaspartate (DL-THA), inhibitors were demonstrated to better inhibit the L-[14C]glutamate uptake under centrifuge-induced hypergravity compared with the normal gravity control. The effect of DL-TBOA on depolarization-induced carrier-mediated L-[14C]glutamate release also increased after hypergravity loading in Na+- and low [Na+] NMDG- supplemented media. 10 µM DL-TBOA-induced decrease in L-[14C]glutamate release in Na+ — supplemented medium was 15.2±2.2 % in the control experiments and 26.2±3.9 % after centrifuge-induced loading (P≤0,05) and in low [Na+] medium was 37.0±2.5 % and 45.0±3.4 %, respectively. More... »

PAGES

230

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02870416

DOI

http://dx.doi.org/10.1007/bf02870416

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1047113270


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "Department of Neurochemistry, Palladin Institute of Biochemistry KAS of Ukraine, Kiev"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Borisova", 
        "givenName": "Tatiana", 
        "id": "sg:person.01230104173.60", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01230104173.60"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Neurochemistry, Palladin Institute of Biochemistry KAS of Ukraine, Kiev"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Krisanova", 
        "givenName": "Natalia", 
        "id": "sg:person.0105352300.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0105352300.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Neurochemistry, Palladin Institute of Biochemistry KAS of Ukraine, Kiev"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Himmelreich", 
        "givenName": "Nina", 
        "id": "sg:person.01016527735.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01016527735.99"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.asr.2003.09.039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008653419"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1248/bpb.27.813", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011318773"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0301-0082(00)00067-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018189315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1097-4547(19980715)53:2<135::aid-jnr2>3.0.co;2-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030422087"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0076-6879(74)31050-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030573040"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1471-4159.2001.00668.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032122509"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0006-8993(99)01235-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035727337"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1471-4159.2000.0751645.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036061822"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076619756", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1124/mol.52.1.6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083117815"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2006-09", 
    "datePublishedReg": "2006-09-01", 
    "description": "The present study evaluated the effect of artificial gravity loading on transporter-mediated uptake and release of L-glutamate using the inhibitors of glutamate transporters as tools. The competitive nontransportable, DL-threo-beta-benzyloxyaspartate (DL-TBOA), and transportable, DL-threo-beta-hydroxyaspartate (DL-THA), inhibitors were demonstrated to better inhibit the L-[14C]glutamate uptake under centrifuge-induced hypergravity compared with the normal gravity control. The effect of DL-TBOA on depolarization-induced carrier-mediated L-[14C]glutamate release also increased after hypergravity loading in Na+- and low [Na+] NMDG- supplemented media. 10 \u00b5M DL-TBOA-induced decrease in L-[14C]glutamate release in Na+ \u2014 supplemented medium was 15.2\u00b12.2 % in the control experiments and 26.2\u00b13.9 % after centrifuge-induced loading (P\u22640,05) and in low [Na+] medium was 37.0\u00b12.5 % and 45.0\u00b13.4 %, respectively.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/bf02870416", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1026232", 
        "issn": [
          "0938-0108", 
          "1875-0494"
        ], 
        "name": "Microgravity Science and Technology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3-4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "18"
      }
    ], 
    "name": "Artificial gravity loading increases the effects of the glutamate transporter inhibitors on the glutamate release and uptake in rat brain nerve terminals", 
    "pagination": "230", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "e06ec3b418390453c64ed1fb86384fd25a8b163916193480e4fc4d4fd63094e6"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf02870416"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1047113270"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf02870416", 
      "https://app.dimensions.ai/details/publication/pub.1047113270"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T13:58", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000371_0000000371/records_130820_00000004.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2FBF02870416"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf02870416'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf02870416'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf02870416'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf02870416'


 

This table displays all metadata directly associated to this object as RDF triples.

107 TRIPLES      21 PREDICATES      37 URIs      19 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf02870416 schema:about anzsrc-for:06
2 anzsrc-for:0601
3 schema:author N17b845dc5e9049c9a3a45f2056621f38
4 schema:citation https://app.dimensions.ai/details/publication/pub.1076619756
5 https://doi.org/10.1002/(sici)1097-4547(19980715)53:2<135::aid-jnr2>3.0.co;2-8
6 https://doi.org/10.1016/0076-6879(74)31050-6
7 https://doi.org/10.1016/j.asr.2003.09.039
8 https://doi.org/10.1016/s0006-8993(99)01235-4
9 https://doi.org/10.1016/s0301-0082(00)00067-8
10 https://doi.org/10.1046/j.1471-4159.2000.0751645.x
11 https://doi.org/10.1046/j.1471-4159.2001.00668.x
12 https://doi.org/10.1124/mol.52.1.6
13 https://doi.org/10.1248/bpb.27.813
14 schema:datePublished 2006-09
15 schema:datePublishedReg 2006-09-01
16 schema:description The present study evaluated the effect of artificial gravity loading on transporter-mediated uptake and release of L-glutamate using the inhibitors of glutamate transporters as tools. The competitive nontransportable, DL-threo-beta-benzyloxyaspartate (DL-TBOA), and transportable, DL-threo-beta-hydroxyaspartate (DL-THA), inhibitors were demonstrated to better inhibit the L-[14C]glutamate uptake under centrifuge-induced hypergravity compared with the normal gravity control. The effect of DL-TBOA on depolarization-induced carrier-mediated L-[14C]glutamate release also increased after hypergravity loading in Na+- and low [Na+] NMDG- supplemented media. 10 µM DL-TBOA-induced decrease in L-[14C]glutamate release in Na+ — supplemented medium was 15.2±2.2 % in the control experiments and 26.2±3.9 % after centrifuge-induced loading (P≤0,05) and in low [Na+] medium was 37.0±2.5 % and 45.0±3.4 %, respectively.
17 schema:genre research_article
18 schema:inLanguage en
19 schema:isAccessibleForFree false
20 schema:isPartOf N248f3fb77a7e44688b3ba291a88ebb29
21 N39e646de38b34b94944ed5241dec4ee7
22 sg:journal.1026232
23 schema:name Artificial gravity loading increases the effects of the glutamate transporter inhibitors on the glutamate release and uptake in rat brain nerve terminals
24 schema:pagination 230
25 schema:productId Nae267cd7bb124109866da3f927031ab0
26 Nd98456fac94b40348c0cadd1c9510fe1
27 Ne42771efc45b45649d47f51fc1917b25
28 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047113270
29 https://doi.org/10.1007/bf02870416
30 schema:sdDatePublished 2019-04-11T13:58
31 schema:sdLicense https://scigraph.springernature.com/explorer/license/
32 schema:sdPublisher Nd7f2d9e5a6d442f9adb0ee397813c872
33 schema:url http://link.springer.com/10.1007%2FBF02870416
34 sgo:license sg:explorer/license/
35 sgo:sdDataset articles
36 rdf:type schema:ScholarlyArticle
37 N0acb5f7715394cc39d0fd1d99e97a374 schema:name Department of Neurochemistry, Palladin Institute of Biochemistry KAS of Ukraine, Kiev
38 rdf:type schema:Organization
39 N0b11710d3870411dbe306448387afc3d schema:name Department of Neurochemistry, Palladin Institute of Biochemistry KAS of Ukraine, Kiev
40 rdf:type schema:Organization
41 N17b845dc5e9049c9a3a45f2056621f38 rdf:first sg:person.01230104173.60
42 rdf:rest N55ae7e8299e84c7c9e17761723aba23e
43 N248f3fb77a7e44688b3ba291a88ebb29 schema:issueNumber 3-4
44 rdf:type schema:PublicationIssue
45 N39e646de38b34b94944ed5241dec4ee7 schema:volumeNumber 18
46 rdf:type schema:PublicationVolume
47 N55ae7e8299e84c7c9e17761723aba23e rdf:first sg:person.0105352300.44
48 rdf:rest N838f8ddb0c00411ea5bc6a6e59fb98c2
49 N838f8ddb0c00411ea5bc6a6e59fb98c2 rdf:first sg:person.01016527735.99
50 rdf:rest rdf:nil
51 N8441ba8d7456465fa63db698f8a1c96d schema:name Department of Neurochemistry, Palladin Institute of Biochemistry KAS of Ukraine, Kiev
52 rdf:type schema:Organization
53 Nae267cd7bb124109866da3f927031ab0 schema:name dimensions_id
54 schema:value pub.1047113270
55 rdf:type schema:PropertyValue
56 Nd7f2d9e5a6d442f9adb0ee397813c872 schema:name Springer Nature - SN SciGraph project
57 rdf:type schema:Organization
58 Nd98456fac94b40348c0cadd1c9510fe1 schema:name doi
59 schema:value 10.1007/bf02870416
60 rdf:type schema:PropertyValue
61 Ne42771efc45b45649d47f51fc1917b25 schema:name readcube_id
62 schema:value e06ec3b418390453c64ed1fb86384fd25a8b163916193480e4fc4d4fd63094e6
63 rdf:type schema:PropertyValue
64 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
65 schema:name Biological Sciences
66 rdf:type schema:DefinedTerm
67 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
68 schema:name Biochemistry and Cell Biology
69 rdf:type schema:DefinedTerm
70 sg:journal.1026232 schema:issn 0938-0108
71 1875-0494
72 schema:name Microgravity Science and Technology
73 rdf:type schema:Periodical
74 sg:person.01016527735.99 schema:affiliation N0acb5f7715394cc39d0fd1d99e97a374
75 schema:familyName Himmelreich
76 schema:givenName Nina
77 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01016527735.99
78 rdf:type schema:Person
79 sg:person.0105352300.44 schema:affiliation N0b11710d3870411dbe306448387afc3d
80 schema:familyName Krisanova
81 schema:givenName Natalia
82 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0105352300.44
83 rdf:type schema:Person
84 sg:person.01230104173.60 schema:affiliation N8441ba8d7456465fa63db698f8a1c96d
85 schema:familyName Borisova
86 schema:givenName Tatiana
87 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01230104173.60
88 rdf:type schema:Person
89 https://app.dimensions.ai/details/publication/pub.1076619756 schema:CreativeWork
90 https://doi.org/10.1002/(sici)1097-4547(19980715)53:2<135::aid-jnr2>3.0.co;2-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030422087
91 rdf:type schema:CreativeWork
92 https://doi.org/10.1016/0076-6879(74)31050-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030573040
93 rdf:type schema:CreativeWork
94 https://doi.org/10.1016/j.asr.2003.09.039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008653419
95 rdf:type schema:CreativeWork
96 https://doi.org/10.1016/s0006-8993(99)01235-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035727337
97 rdf:type schema:CreativeWork
98 https://doi.org/10.1016/s0301-0082(00)00067-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018189315
99 rdf:type schema:CreativeWork
100 https://doi.org/10.1046/j.1471-4159.2000.0751645.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1036061822
101 rdf:type schema:CreativeWork
102 https://doi.org/10.1046/j.1471-4159.2001.00668.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1032122509
103 rdf:type schema:CreativeWork
104 https://doi.org/10.1124/mol.52.1.6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083117815
105 rdf:type schema:CreativeWork
106 https://doi.org/10.1248/bpb.27.813 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011318773
107 rdf:type schema:CreativeWork
 




Preview window. Press ESC to close (or click here)


...