Estimation of cell DNA synthesis rate from flow-cytometric histograms View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1983-12

AUTHORS

A. Bertuzzi, A. Gandolfi, A. Germani, R. Vitelli

ABSTRACT

The rate of DNA synthesis along S-phase can be estimated on the basis of a simple model of a cell population, from a single FCM histogram under conditions of balanced exponential growth, and from two histograms suitably spaced in time under conditions of locally exponential S-phase influx. An algorithm that constructs a piecewise constant approximation of the synthesis rate and estimates the phase fractions from a single histogram is presented. The results of the application of the algorithm to a set of computer generated histograms in balanced exponential growth are reported. More... »

PAGES

223-236

References to SciGraph publications

  • 1982-03. Error analysis in flow microfluorometry in CELL BIOCHEMISTRY AND BIOPHYSICS
  • 1983-03. On the inverse problem in flow cytometry recovering DNA distribution from FMF data in CELL BIOCHEMISTRY AND BIOPHYSICS
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf02788622

    DOI

    http://dx.doi.org/10.1007/bf02788622

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1000183261

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/6202409


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