Histochemical properties of vascular and sinusoidal endothelial cells in liver diseases View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1991-06

AUTHORS

Masami Hattori, Yoshihide Fukuda, Masami Imoto, Yasuo Koyama, Isao Nakano, Fumihiro Urano

ABSTRACT

Liver biopsy specimens with or without liver diseases were examined immunohistochemically to determine the distribution of endothelial cell markers, factor VIII-related antigen (FVIII-RAg), Ulex europaeus agglutinin I (UEA-I) lectin and PAL-E. We also investigated the localization of laminin, a component of the basement membrane. In normal livers, FVIII-RAg, UEA-I and laminin were negative in sinusoidal endothelial cells, but positive in blood vascular endothelia of the portal area. The antigen detected by PAL-E was distributed in venous endothelial cells. PAL-E did not label endothelial cells of the artery. In the lobule, immunoreactivity with PAL-E was weakly detected only in some sinusoids of the periportal area. In chronic active hepatitis and liver cirrhosis, FVIII-RAg and UEA-I stained endothelial cells of neovasculatures in the enlarged portal areas of the fibrous septum surrounding pseudolobules. Some sinusoidal endothelial cells in cirrhotic livers were reactive to UEA-I and FVIII-RAg, whereas PAL-E-positive cells were found rarely in the pseudolobules. In carcinomatous sinusoidal endothelial cells, FVIII-RAg, UEA-I and PAL-E were strongly stained. Laminin underlay these carcinomatous sinusoids. These suggest capillarization of sinusoids in hepatocellular carcinoma. The histochemical approach using endothelial cell markers could be a practical tool in the diagnosis of hepatocellular carcinoma. More... »

PAGES

336-343

References to SciGraph publications

  • 1989-01. Microvasculature in the small portal tracts in idiopathic portal hypertension in VIRCHOWS ARCHIV A PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf02781922

    DOI

    http://dx.doi.org/10.1007/bf02781922

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1077203238

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/1653746


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Cardiorespiratory Medicine and Haematology", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Antibodies, Monoclonal", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Biomarkers", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Carcinoma, Hepatocellular", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Endothelium, Vascular", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Hepatitis, Chronic", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Immunohistochemistry", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Laminin", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Lectins", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Liver", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Liver Cirrhosis", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Liver Neoplasms", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Plant Lectins", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Portal Vein", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "von Willebrand Factor", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Second Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsuruma-cho, Showa-ku, 466, Nagoya, Japan", 
              "id": "http://www.grid.ac/institutes/grid.27476.30", 
              "name": [
                "Second Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsuruma-cho, Showa-ku, 466, Nagoya, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hattori", 
            "givenName": "Masami", 
            "id": "sg:person.0713516154.10", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713516154.10"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Second Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsuruma-cho, Showa-ku, 466, Nagoya, Japan", 
              "id": "http://www.grid.ac/institutes/grid.27476.30", 
              "name": [
                "Second Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsuruma-cho, Showa-ku, 466, Nagoya, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Fukuda", 
            "givenName": "Yoshihide", 
            "id": "sg:person.01070564772.15", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070564772.15"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Second Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsuruma-cho, Showa-ku, 466, Nagoya, Japan", 
              "id": "http://www.grid.ac/institutes/grid.27476.30", 
              "name": [
                "Second Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsuruma-cho, Showa-ku, 466, Nagoya, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Imoto", 
            "givenName": "Masami", 
            "id": "sg:person.01253352541.81", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01253352541.81"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Second Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsuruma-cho, Showa-ku, 466, Nagoya, Japan", 
              "id": "http://www.grid.ac/institutes/grid.27476.30", 
              "name": [
                "Second Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsuruma-cho, Showa-ku, 466, Nagoya, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Koyama", 
            "givenName": "Yasuo", 
            "id": "sg:person.01136700172.14", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01136700172.14"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Second Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsuruma-cho, Showa-ku, 466, Nagoya, Japan", 
              "id": "http://www.grid.ac/institutes/grid.27476.30", 
              "name": [
                "Second Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsuruma-cho, Showa-ku, 466, Nagoya, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Nakano", 
            "givenName": "Isao", 
            "id": "sg:person.0725124117.09", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0725124117.09"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Second Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsuruma-cho, Showa-ku, 466, Nagoya, Japan", 
              "id": "http://www.grid.ac/institutes/grid.27476.30", 
              "name": [
                "Second Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsuruma-cho, Showa-ku, 466, Nagoya, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Urano", 
            "givenName": "Fumihiro", 
            "id": "sg:person.01152647366.31", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152647366.31"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1007/bf00718605", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046942311", 
              "https://doi.org/10.1007/bf00718605"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "1991-06", 
        "datePublishedReg": "1991-06-01", 
        "description": "Liver biopsy specimens with or without liver diseases were examined immunohistochemically to determine the distribution of endothelial cell markers, factor VIII-related antigen (FVIII-RAg), Ulex europaeus agglutinin I (UEA-I) lectin and PAL-E. We also investigated the localization of laminin, a component of the basement membrane. In normal livers, FVIII-RAg, UEA-I and laminin were negative in sinusoidal endothelial cells, but positive in blood vascular endothelia of the portal area. The antigen detected by PAL-E was distributed in venous endothelial cells. PAL-E did not label endothelial cells of the artery. In the lobule, immunoreactivity with PAL-E was weakly detected only in some sinusoids of the periportal area. In chronic active hepatitis and liver cirrhosis, FVIII-RAg and UEA-I stained endothelial cells of neovasculatures in the enlarged portal areas of the fibrous septum surrounding pseudolobules. Some sinusoidal endothelial cells in cirrhotic livers were reactive to UEA-I and FVIII-RAg, whereas PAL-E-positive cells were found rarely in the pseudolobules. In carcinomatous sinusoidal endothelial cells, FVIII-RAg, UEA-I and PAL-E were strongly stained. Laminin underlay these carcinomatous sinusoids. These suggest capillarization of sinusoids in hepatocellular carcinoma. The histochemical approach using endothelial cell markers could be a practical tool in the diagnosis of hepatocellular carcinoma.", 
        "genre": "article", 
        "id": "sg:pub.10.1007/bf02781922", 
        "inLanguage": "en", 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1009747", 
            "issn": [
              "0944-1174", 
              "1435-5922"
            ], 
            "name": "Journal of Gastroenterology", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "3", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "26"
          }
        ], 
        "keywords": [
          "factor VIII-related antigen", 
          "sinusoidal endothelial cells", 
          "endothelial cell markers", 
          "endothelial cells", 
          "liver disease", 
          "portal areas", 
          "hepatocellular carcinoma", 
          "Ulex europaeus agglutinin I (UEA-I) lectin", 
          "cell markers", 
          "VIII-related antigen", 
          "capillarization of sinusoids", 
          "chronic active hepatitis", 
          "venous endothelial cells", 
          "active hepatitis", 
          "blood vascular endothelium", 
          "liver biopsy", 
          "liver cirrhosis", 
          "localization of laminin", 
          "vascular endothelium", 
          "cirrhotic liver", 
          "positive cells", 
          "fibrous septa", 
          "periportal areas", 
          "normal liver", 
          "histochemical properties", 
          "basement membrane", 
          "carcinoma", 
          "disease", 
          "antigen", 
          "UEA", 
          "liver", 
          "pseudolobules", 
          "histochemical approach", 
          "cells", 
          "laminin", 
          "markers", 
          "hepatitis", 
          "cirrhosis", 
          "biopsy", 
          "artery", 
          "sinusoids", 
          "immunoreactivity", 
          "endothelium", 
          "capillarization", 
          "diagnosis", 
          "lobule", 
          "neovasculature", 
          "septum", 
          "lectin", 
          "area", 
          "PAL", 
          "localization", 
          "practical tool", 
          "membrane", 
          "tool", 
          "components", 
          "approach", 
          "distribution", 
          "properties", 
          "europaeus agglutinin I (UEA-I) lectin", 
          "agglutinin I (UEA-I) lectin", 
          "I (UEA-I) lectin", 
          "carcinomatous sinusoidal endothelial cells", 
          "carcinomatous sinusoids"
        ], 
        "name": "Histochemical properties of vascular and sinusoidal endothelial cells in liver diseases", 
        "pagination": "336-343", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1077203238"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/bf02781922"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "1653746"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/bf02781922", 
          "https://app.dimensions.ai/details/publication/pub.1077203238"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-01-01T18:05", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/article/article_226.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1007/bf02781922"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf02781922'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf02781922'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf02781922'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf02781922'


     

    This table displays all metadata directly associated to this object as RDF triples.

    225 TRIPLES      22 PREDICATES      107 URIs      98 LITERALS      22 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/bf02781922 schema:about N02e562e2763e43169e6903e3a568e29a
    2 N078f95a4230c4bffb697d5da02902db8
    3 N0cb155086b66483d94e0e994a9c2d15d
    4 N27061ec06bc44a7b831f22e8e9069ec6
    5 N67e7b4137da84e219367cd9d358d604d
    6 N6e7629047a884a5bbb4201492edafe88
    7 N73cfc457083444e8a4c8906cff657eea
    8 N7c2c7b7de05b43f6b4f714488d86c810
    9 N96a0322a487f477e9651bc8b14c429c7
    10 Nbe6c278999ac405693ee666a54d761ab
    11 Nca21ecbeae80475d8f188a258ea5fb1f
    12 Ncc8b4835a85949c8bfa6d34bf7b03baf
    13 Nd2c75df7fc55451f9410bc66dde4377b
    14 Nede555612c074ac68eafcd61fa82f6cf
    15 Nf814184cfcbe41ba87cf7c091268c395
    16 anzsrc-for:11
    17 anzsrc-for:1102
    18 schema:author N99befe957d4944cab152e0dffcaa516b
    19 schema:citation sg:pub.10.1007/bf00718605
    20 schema:datePublished 1991-06
    21 schema:datePublishedReg 1991-06-01
    22 schema:description Liver biopsy specimens with or without liver diseases were examined immunohistochemically to determine the distribution of endothelial cell markers, factor VIII-related antigen (FVIII-RAg), Ulex europaeus agglutinin I (UEA-I) lectin and PAL-E. We also investigated the localization of laminin, a component of the basement membrane. In normal livers, FVIII-RAg, UEA-I and laminin were negative in sinusoidal endothelial cells, but positive in blood vascular endothelia of the portal area. The antigen detected by PAL-E was distributed in venous endothelial cells. PAL-E did not label endothelial cells of the artery. In the lobule, immunoreactivity with PAL-E was weakly detected only in some sinusoids of the periportal area. In chronic active hepatitis and liver cirrhosis, FVIII-RAg and UEA-I stained endothelial cells of neovasculatures in the enlarged portal areas of the fibrous septum surrounding pseudolobules. Some sinusoidal endothelial cells in cirrhotic livers were reactive to UEA-I and FVIII-RAg, whereas PAL-E-positive cells were found rarely in the pseudolobules. In carcinomatous sinusoidal endothelial cells, FVIII-RAg, UEA-I and PAL-E were strongly stained. Laminin underlay these carcinomatous sinusoids. These suggest capillarization of sinusoids in hepatocellular carcinoma. The histochemical approach using endothelial cell markers could be a practical tool in the diagnosis of hepatocellular carcinoma.
    23 schema:genre article
    24 schema:inLanguage en
    25 schema:isAccessibleForFree false
    26 schema:isPartOf N0abe3f23750a438abb6355fdf553c196
    27 Ne4d6cd598faf46f0b9d50ec7aeeb5f64
    28 sg:journal.1009747
    29 schema:keywords I (UEA-I) lectin
    30 PAL
    31 UEA
    32 Ulex europaeus agglutinin I (UEA-I) lectin
    33 VIII-related antigen
    34 active hepatitis
    35 agglutinin I (UEA-I) lectin
    36 antigen
    37 approach
    38 area
    39 artery
    40 basement membrane
    41 biopsy
    42 blood vascular endothelium
    43 capillarization
    44 capillarization of sinusoids
    45 carcinoma
    46 carcinomatous sinusoidal endothelial cells
    47 carcinomatous sinusoids
    48 cell markers
    49 cells
    50 chronic active hepatitis
    51 cirrhosis
    52 cirrhotic liver
    53 components
    54 diagnosis
    55 disease
    56 distribution
    57 endothelial cell markers
    58 endothelial cells
    59 endothelium
    60 europaeus agglutinin I (UEA-I) lectin
    61 factor VIII-related antigen
    62 fibrous septa
    63 hepatitis
    64 hepatocellular carcinoma
    65 histochemical approach
    66 histochemical properties
    67 immunoreactivity
    68 laminin
    69 lectin
    70 liver
    71 liver biopsy
    72 liver cirrhosis
    73 liver disease
    74 lobule
    75 localization
    76 localization of laminin
    77 markers
    78 membrane
    79 neovasculature
    80 normal liver
    81 periportal areas
    82 portal areas
    83 positive cells
    84 practical tool
    85 properties
    86 pseudolobules
    87 septum
    88 sinusoidal endothelial cells
    89 sinusoids
    90 tool
    91 vascular endothelium
    92 venous endothelial cells
    93 schema:name Histochemical properties of vascular and sinusoidal endothelial cells in liver diseases
    94 schema:pagination 336-343
    95 schema:productId N232974331fc6470995e008db5abe4dcf
    96 Nb58d3ae3ea7c4b9b840da4d4c21524aa
    97 Ncf9214cfa3714866a16f4eae26b7b039
    98 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077203238
    99 https://doi.org/10.1007/bf02781922
    100 schema:sdDatePublished 2022-01-01T18:05
    101 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    102 schema:sdPublisher Ne655f3f0c2bd4b5cac09118149571bc7
    103 schema:url https://doi.org/10.1007/bf02781922
    104 sgo:license sg:explorer/license/
    105 sgo:sdDataset articles
    106 rdf:type schema:ScholarlyArticle
    107 N02e562e2763e43169e6903e3a568e29a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    108 schema:name Humans
    109 rdf:type schema:DefinedTerm
    110 N078f95a4230c4bffb697d5da02902db8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    111 schema:name Carcinoma, Hepatocellular
    112 rdf:type schema:DefinedTerm
    113 N0abe3f23750a438abb6355fdf553c196 schema:volumeNumber 26
    114 rdf:type schema:PublicationVolume
    115 N0cb155086b66483d94e0e994a9c2d15d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    116 schema:name Immunohistochemistry
    117 rdf:type schema:DefinedTerm
    118 N232974331fc6470995e008db5abe4dcf schema:name dimensions_id
    119 schema:value pub.1077203238
    120 rdf:type schema:PropertyValue
    121 N27061ec06bc44a7b831f22e8e9069ec6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    122 schema:name Liver Neoplasms
    123 rdf:type schema:DefinedTerm
    124 N2842448da0614471b92bd49655e3fea0 rdf:first sg:person.01152647366.31
    125 rdf:rest rdf:nil
    126 N67e7b4137da84e219367cd9d358d604d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    127 schema:name von Willebrand Factor
    128 rdf:type schema:DefinedTerm
    129 N6e7629047a884a5bbb4201492edafe88 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    130 schema:name Portal Vein
    131 rdf:type schema:DefinedTerm
    132 N73cfc457083444e8a4c8906cff657eea schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    133 schema:name Hepatitis, Chronic
    134 rdf:type schema:DefinedTerm
    135 N7c2c7b7de05b43f6b4f714488d86c810 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    136 schema:name Liver Cirrhosis
    137 rdf:type schema:DefinedTerm
    138 N87506a97e226433c9d0ae47b04338914 rdf:first sg:person.01253352541.81
    139 rdf:rest N9ebc466f6441427e93ad269a8d7bf95d
    140 N87d14efdc4bb44aeb483150d0d90bd8c rdf:first sg:person.0725124117.09
    141 rdf:rest N2842448da0614471b92bd49655e3fea0
    142 N96a0322a487f477e9651bc8b14c429c7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    143 schema:name Antibodies, Monoclonal
    144 rdf:type schema:DefinedTerm
    145 N99befe957d4944cab152e0dffcaa516b rdf:first sg:person.0713516154.10
    146 rdf:rest Nbf0146d3f100451bb9313f4567683fe8
    147 N9ebc466f6441427e93ad269a8d7bf95d rdf:first sg:person.01136700172.14
    148 rdf:rest N87d14efdc4bb44aeb483150d0d90bd8c
    149 Nb58d3ae3ea7c4b9b840da4d4c21524aa schema:name pubmed_id
    150 schema:value 1653746
    151 rdf:type schema:PropertyValue
    152 Nbe6c278999ac405693ee666a54d761ab schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    153 schema:name Liver
    154 rdf:type schema:DefinedTerm
    155 Nbf0146d3f100451bb9313f4567683fe8 rdf:first sg:person.01070564772.15
    156 rdf:rest N87506a97e226433c9d0ae47b04338914
    157 Nca21ecbeae80475d8f188a258ea5fb1f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    158 schema:name Laminin
    159 rdf:type schema:DefinedTerm
    160 Ncc8b4835a85949c8bfa6d34bf7b03baf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    161 schema:name Endothelium, Vascular
    162 rdf:type schema:DefinedTerm
    163 Ncf9214cfa3714866a16f4eae26b7b039 schema:name doi
    164 schema:value 10.1007/bf02781922
    165 rdf:type schema:PropertyValue
    166 Nd2c75df7fc55451f9410bc66dde4377b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    167 schema:name Lectins
    168 rdf:type schema:DefinedTerm
    169 Ne4d6cd598faf46f0b9d50ec7aeeb5f64 schema:issueNumber 3
    170 rdf:type schema:PublicationIssue
    171 Ne655f3f0c2bd4b5cac09118149571bc7 schema:name Springer Nature - SN SciGraph project
    172 rdf:type schema:Organization
    173 Nede555612c074ac68eafcd61fa82f6cf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    174 schema:name Biomarkers
    175 rdf:type schema:DefinedTerm
    176 Nf814184cfcbe41ba87cf7c091268c395 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    177 schema:name Plant Lectins
    178 rdf:type schema:DefinedTerm
    179 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    180 schema:name Medical and Health Sciences
    181 rdf:type schema:DefinedTerm
    182 anzsrc-for:1102 schema:inDefinedTermSet anzsrc-for:
    183 schema:name Cardiorespiratory Medicine and Haematology
    184 rdf:type schema:DefinedTerm
    185 sg:journal.1009747 schema:issn 0944-1174
    186 1435-5922
    187 schema:name Journal of Gastroenterology
    188 schema:publisher Springer Nature
    189 rdf:type schema:Periodical
    190 sg:person.01070564772.15 schema:affiliation grid-institutes:grid.27476.30
    191 schema:familyName Fukuda
    192 schema:givenName Yoshihide
    193 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01070564772.15
    194 rdf:type schema:Person
    195 sg:person.01136700172.14 schema:affiliation grid-institutes:grid.27476.30
    196 schema:familyName Koyama
    197 schema:givenName Yasuo
    198 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01136700172.14
    199 rdf:type schema:Person
    200 sg:person.01152647366.31 schema:affiliation grid-institutes:grid.27476.30
    201 schema:familyName Urano
    202 schema:givenName Fumihiro
    203 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152647366.31
    204 rdf:type schema:Person
    205 sg:person.01253352541.81 schema:affiliation grid-institutes:grid.27476.30
    206 schema:familyName Imoto
    207 schema:givenName Masami
    208 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01253352541.81
    209 rdf:type schema:Person
    210 sg:person.0713516154.10 schema:affiliation grid-institutes:grid.27476.30
    211 schema:familyName Hattori
    212 schema:givenName Masami
    213 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0713516154.10
    214 rdf:type schema:Person
    215 sg:person.0725124117.09 schema:affiliation grid-institutes:grid.27476.30
    216 schema:familyName Nakano
    217 schema:givenName Isao
    218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0725124117.09
    219 rdf:type schema:Person
    220 sg:pub.10.1007/bf00718605 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046942311
    221 https://doi.org/10.1007/bf00718605
    222 rdf:type schema:CreativeWork
    223 grid-institutes:grid.27476.30 schema:alternateName Second Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsuruma-cho, Showa-ku, 466, Nagoya, Japan
    224 schema:name Second Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsuruma-cho, Showa-ku, 466, Nagoya, Japan
    225 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...