Clinical significance of e-antigen/anti-e, with special reference to HBc-antigen in the liver View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1977-12

AUTHORS

Seiichi Furuta, Kendo Kiyosawa, Atsuo Nagata, Yuriko Koike, Takeshi Sahara, Kenichi Furukawa, Yoshihiro Iijima, Shinkichi Yamamura, Hironao Komatsu, Kenziro Kawahara, Masazumi Miura, Yukio Gibo, Ken Sodeyama, Masayuki Oda, Fumio Tsuda, Yoshihiro Akahane, Makoto Mayumi

ABSTRACT

e-antigen and anti-e were assayed in sera of asymptomatic HBs-Ag carriers and of patients with liver diseases. Thirteen out of 34 (38.2%) asymptomatic carriers were positive for e-antigen, which was in sharp contrast to the reports from USA and Europe. e-antigen was detected to a greater extent in patients with chronic active hepatitis, reversely anti-e in patients with chronic persistent hepatitis. However, e-antigen was found rarely in patients with cirrhosis and never in 23 cases with hepatoma positive for HBs-Ag. HBc-Ag in the liver was detected in 4 out of 8 e-antigen positive asymptomatic carriers and in 4 out of 5 patients with chronic liver diseases with e-antigen respectively, and moreover in 3 out of 14 anti-e positive cases, so that the presence of anti-e did not necessarily mean the negativity of HBc-Ag in the liver. Anti-HBc titer, however, was lower in anti-e positive sera than in e-antigen positive ones. This may implicate the decreased replication of HBV in cases with anti-e. These results emphasize that the investigation of e-antigen/anti-e is mandatory for the evaluation of the prognosis of asymptomatic carriers and of patients with chronic hepatitis. More... »

PAGES

460-465

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02781338

DOI

http://dx.doi.org/10.1007/bf02781338

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1081559399

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/608568


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Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf02781338'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf02781338'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf02781338'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf02781338'


 

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