The antiphospholipid syndrome View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1995-03

AUTHORS

E. Nigel Harris

ABSTRACT

Much more is known about the APLS than 15 yr ago, but more needs to be done. Clinically, major characteristics of the disorder have been defined, but the course of the disease and its relationship to other disorders, such as systemic lupus erythematosus (SLE), need to be defined. Good progress has been made in standardizing anticardiolipin and, to a lesser extent, LA. However, problems with interlaboratory and inter-assay variation need to be addressed. Doctors are getting a better idea of how to manage these patients with a view to preventing recurrences of thrombosis or pregnancy losses, but prospective studies are still desirable to give more definitive answers. Attention has turned to the pathogenesis of the disorder. It seems likely that antibodies mediate the clinical disorders with which they are associated, but the mechanisms by which this occurs still require further study. More... »

PAGES

39-48

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02772247

DOI

http://dx.doi.org/10.1007/bf02772247

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1053622480

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/7648347


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antibodies, Anticardiolipin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antiphospholipid Syndrome", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lupus Coagulation Inhibitor", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Thrombosis", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Medicine, Division of Rheumatology, University of Louisville, 40292, Louisville, KY", 
          "id": "http://www.grid.ac/institutes/grid.266623.5", 
          "name": [
            "Department of Medicine, Division of Rheumatology, University of Louisville, 40292, Louisville, KY"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Harris", 
        "givenName": "E. Nigel", 
        "id": "sg:person.011340100772.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011340100772.08"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "1995-03", 
    "datePublishedReg": "1995-03-01", 
    "description": "Much more is known about the APLS than 15 yr ago, but more needs to be done. Clinically, major characteristics of the disorder have been defined, but the course of the disease and its relationship to other disorders, such as systemic lupus erythematosus (SLE), need to be defined. Good progress has been made in standardizing anticardiolipin and, to a lesser extent, LA. However, problems with interlaboratory and inter-assay variation need to be addressed. Doctors are getting a better idea of how to manage these patients with a view to preventing recurrences of thrombosis or pregnancy losses, but prospective studies are still desirable to give more definitive answers. Attention has turned to the pathogenesis of the disorder. It seems likely that antibodies mediate the clinical disorders with which they are associated, but the mechanisms by which this occurs still require further study.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/bf02772247", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1094155", 
        "issn": [
          "1080-0549", 
          "1559-0267"
        ], 
        "name": "Clinical Reviews in Allergy & Immunology", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "13"
      }
    ], 
    "keywords": [
      "systemic lupus erythematosus", 
      "recurrence of thrombosis", 
      "antiphospholipid syndrome", 
      "lupus erythematosus", 
      "prospective study", 
      "pregnancy loss", 
      "clinical disorders", 
      "disorders", 
      "inter-assay variation", 
      "Further studies", 
      "definitive answer", 
      "lesser extent", 
      "anticardiolipin", 
      "erythematosus", 
      "thrombosis", 
      "patients", 
      "aPLs", 
      "recurrence", 
      "pathogenesis", 
      "syndrome", 
      "more needs", 
      "disease", 
      "antibodies", 
      "doctors", 
      "study", 
      "good progress", 
      "course", 
      "yr", 
      "major characteristics", 
      "interlaboratory", 
      "loss", 
      "mechanism", 
      "need", 
      "extent", 
      "relationship", 
      "progress", 
      "characteristics", 
      "attention", 
      "good idea", 
      "La", 
      "view", 
      "variation", 
      "answers", 
      "problem", 
      "idea"
    ], 
    "name": "The antiphospholipid syndrome", 
    "pagination": "39-48", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1053622480"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf02772247"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "7648347"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf02772247", 
      "https://app.dimensions.ai/details/publication/pub.1053622480"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-05-20T07:19", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/article/article_265.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/bf02772247"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf02772247'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf02772247'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf02772247'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf02772247'


 

This table displays all metadata directly associated to this object as RDF triples.

127 TRIPLES      21 PREDICATES      77 URIs      69 LITERALS      12 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf02772247 schema:about N61cac04e215a47b989709793cd096cfb
2 N8072cdc93d074442a1a97c8f4880e37e
3 N86c1ff7c5c6b441eb1c3035d4582ff13
4 N8f5cc179f296464fb17f44ef7058d44b
5 Ndae551d276a842a3a388dbbc4fb0b377
6 anzsrc-for:11
7 anzsrc-for:1103
8 schema:author Nfd7dd3ab97d74d97b25265d9e4b1a55b
9 schema:datePublished 1995-03
10 schema:datePublishedReg 1995-03-01
11 schema:description Much more is known about the APLS than 15 yr ago, but more needs to be done. Clinically, major characteristics of the disorder have been defined, but the course of the disease and its relationship to other disorders, such as systemic lupus erythematosus (SLE), need to be defined. Good progress has been made in standardizing anticardiolipin and, to a lesser extent, LA. However, problems with interlaboratory and inter-assay variation need to be addressed. Doctors are getting a better idea of how to manage these patients with a view to preventing recurrences of thrombosis or pregnancy losses, but prospective studies are still desirable to give more definitive answers. Attention has turned to the pathogenesis of the disorder. It seems likely that antibodies mediate the clinical disorders with which they are associated, but the mechanisms by which this occurs still require further study.
12 schema:genre article
13 schema:inLanguage en
14 schema:isAccessibleForFree false
15 schema:isPartOf N6eaea8b5eb4e483a858c3ebf3cf35ae7
16 N7a4f9372f6364fdc9b92dc2588c4e99b
17 sg:journal.1094155
18 schema:keywords Further studies
19 La
20 aPLs
21 answers
22 antibodies
23 anticardiolipin
24 antiphospholipid syndrome
25 attention
26 characteristics
27 clinical disorders
28 course
29 definitive answer
30 disease
31 disorders
32 doctors
33 erythematosus
34 extent
35 good idea
36 good progress
37 idea
38 inter-assay variation
39 interlaboratory
40 lesser extent
41 loss
42 lupus erythematosus
43 major characteristics
44 mechanism
45 more needs
46 need
47 pathogenesis
48 patients
49 pregnancy loss
50 problem
51 progress
52 prospective study
53 recurrence
54 recurrence of thrombosis
55 relationship
56 study
57 syndrome
58 systemic lupus erythematosus
59 thrombosis
60 variation
61 view
62 yr
63 schema:name The antiphospholipid syndrome
64 schema:pagination 39-48
65 schema:productId N1b2bed6935714dcf9b1d057604a00816
66 N679d1e87713a4b2ab844342427a932a9
67 Nc399e4d3290e479987412567c4a496c3
68 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053622480
69 https://doi.org/10.1007/bf02772247
70 schema:sdDatePublished 2022-05-20T07:19
71 schema:sdLicense https://scigraph.springernature.com/explorer/license/
72 schema:sdPublisher N606572528b7c4c14905294cdd1638dbf
73 schema:url https://doi.org/10.1007/bf02772247
74 sgo:license sg:explorer/license/
75 sgo:sdDataset articles
76 rdf:type schema:ScholarlyArticle
77 N1b2bed6935714dcf9b1d057604a00816 schema:name pubmed_id
78 schema:value 7648347
79 rdf:type schema:PropertyValue
80 N606572528b7c4c14905294cdd1638dbf schema:name Springer Nature - SN SciGraph project
81 rdf:type schema:Organization
82 N61cac04e215a47b989709793cd096cfb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Lupus Coagulation Inhibitor
84 rdf:type schema:DefinedTerm
85 N679d1e87713a4b2ab844342427a932a9 schema:name dimensions_id
86 schema:value pub.1053622480
87 rdf:type schema:PropertyValue
88 N6eaea8b5eb4e483a858c3ebf3cf35ae7 schema:volumeNumber 13
89 rdf:type schema:PublicationVolume
90 N7a4f9372f6364fdc9b92dc2588c4e99b schema:issueNumber 1
91 rdf:type schema:PublicationIssue
92 N8072cdc93d074442a1a97c8f4880e37e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Antibodies, Anticardiolipin
94 rdf:type schema:DefinedTerm
95 N86c1ff7c5c6b441eb1c3035d4582ff13 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Antiphospholipid Syndrome
97 rdf:type schema:DefinedTerm
98 N8f5cc179f296464fb17f44ef7058d44b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Thrombosis
100 rdf:type schema:DefinedTerm
101 Nc399e4d3290e479987412567c4a496c3 schema:name doi
102 schema:value 10.1007/bf02772247
103 rdf:type schema:PropertyValue
104 Ndae551d276a842a3a388dbbc4fb0b377 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Humans
106 rdf:type schema:DefinedTerm
107 Nfd7dd3ab97d74d97b25265d9e4b1a55b rdf:first sg:person.011340100772.08
108 rdf:rest rdf:nil
109 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
110 schema:name Medical and Health Sciences
111 rdf:type schema:DefinedTerm
112 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
113 schema:name Clinical Sciences
114 rdf:type schema:DefinedTerm
115 sg:journal.1094155 schema:issn 1080-0549
116 1559-0267
117 schema:name Clinical Reviews in Allergy & Immunology
118 schema:publisher Springer Nature
119 rdf:type schema:Periodical
120 sg:person.011340100772.08 schema:affiliation grid-institutes:grid.266623.5
121 schema:familyName Harris
122 schema:givenName E. Nigel
123 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011340100772.08
124 rdf:type schema:Person
125 grid-institutes:grid.266623.5 schema:alternateName Department of Medicine, Division of Rheumatology, University of Louisville, 40292, Louisville, KY
126 schema:name Department of Medicine, Division of Rheumatology, University of Louisville, 40292, Louisville, KY
127 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...