MIR: Family of repeats common to vertebrate genomes View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2000-07

AUTHORS

E. V. Korotkov, M. A. Korotkova, V. M. Rudenko

ABSTRACT

We studied the occurrence of mammalian interspersed repeats (MIRs) in DNA and RNA of vertebrates, invertebrates, and bacteria using the data from GenBank. A special algorithm based on a weight position matrix with optimal alignment using dynamic programming was developed to search for the traces of MIR dissemination. This allowed us to search for highly divergent MIRs carrying deletions and insertions. MIRs were detected in genomes of various fishes, includingLatimeria. This suggests that the origin of MIRs dates back more than 400 million years. The method to search for similarity between highly divergent sequences may be used to find the genome fragments from various ancient repeat families and from various gene families. More... »

PAGES

468-473

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02759556

DOI

http://dx.doi.org/10.1007/bf02759556

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1018599264


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