Interaction andin vivo growth inhibition of Ehrlich ascites tumor cells by jacalin View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1988-12-01

AUTHORS

H. Ahmed, B. P. Chatterjee, A. K. Debnath

ABSTRACT

Jacalin has been found to agglutinate Ehrlich ascites cells. The agglutination was inhibited by α-glycosides of D-Gal and β -D-Gal(1 → 3)-D-GalNAc suggesting that the lectin-ascites interaction was carbohydrate-specific. There was 21.8% inhibition of tumour (ascites) cell growthin vivo in mice administered 50μg of jacalin by injection for 6 days following intraperitoneal injection of ascites cells. Administration of 100, 150 and 200μg jacalin resulted in 40.2, 57.5 and 83% inhibition respectively. Thein vivo inhibition of tumour cells growth by jacalin was due to its preferential binding with D-Gal-α -(1 → 6) present as terminal residues in the glycoprotein on tumour cell surface. More... »

PAGES

419-424

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02703454

DOI

http://dx.doi.org/10.1007/bf02703454

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1013649412


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Biological Chemistry, Indian Association for the Cultivation of Science, Jadavpur, 700 032, Calcutta, India", 
          "id": "http://www.grid.ac/institutes/grid.417929.0", 
          "name": [
            "Department of Biological Chemistry, Indian Association for the Cultivation of Science, Jadavpur, 700 032, Calcutta, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ahmed", 
        "givenName": "H.", 
        "id": "sg:person.01322353577.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01322353577.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biological Chemistry, Indian Association for the Cultivation of Science, Jadavpur, 700 032, Calcutta, India", 
          "id": "http://www.grid.ac/institutes/grid.417929.0", 
          "name": [
            "Department of Biological Chemistry, Indian Association for the Cultivation of Science, Jadavpur, 700 032, Calcutta, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chatterjee", 
        "givenName": "B. P.", 
        "id": "sg:person.01026226762.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01026226762.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biological Chemistry, Indian Association for the Cultivation of Science, Jadavpur, 700 032, Calcutta, India", 
          "id": "http://www.grid.ac/institutes/grid.417929.0", 
          "name": [
            "Department of Biological Chemistry, Indian Association for the Cultivation of Science, Jadavpur, 700 032, Calcutta, India"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Debnath", 
        "givenName": "A. K.", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf01618550", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041991745", 
          "https://doi.org/10.1007/bf01618550"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02702736", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047326001", 
          "https://doi.org/10.1007/bf02702736"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1988-12-01", 
    "datePublishedReg": "1988-12-01", 
    "description": "Jacalin has been found to agglutinate Ehrlich ascites cells. The agglutination was inhibited by \u03b1-glycosides of D-Gal and \u03b2 -D-Gal(1 \u2192 3)-D-GalNAc suggesting that the lectin-ascites interaction was carbohydrate-specific. There was 21.8% inhibition of tumour (ascites) cell growthin vivo in mice administered 50\u03bcg of jacalin by injection for 6 days following intraperitoneal injection of ascites cells. Administration of 100, 150 and 200\u03bcg jacalin resulted in 40.2, 57.5 and 83% inhibition respectively. Thein vivo inhibition of tumour cells growth by jacalin was due to its preferential binding with D-Gal-\u03b1 -(1 \u2192 6) present as terminal residues in the glycoprotein on tumour cell surface.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/bf02703454", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1092026", 
        "issn": [
          "0253-410X", 
          "0973-7138"
        ], 
        "name": "Journal of Biosciences", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "13"
      }
    ], 
    "keywords": [
      "tumor cell growth", 
      "tumor cell surface", 
      "intraperitoneal injection", 
      "tumor cells", 
      "growth inhibition", 
      "inhibition", 
      "injection", 
      "cell growth", 
      "ascites cells", 
      "cells", 
      "cell surface", 
      "Ehrlich", 
      "mice", 
      "administration", 
      "jacalin", 
      "Gal", 
      "vivo", 
      "days", 
      "agglutination", 
      "glycoprotein", 
      "andin", 
      "preferential binding", 
      "GalNAc", 
      "binding", 
      "terminal residues", 
      "glycosides", 
      "thein", 
      "growth", 
      "interaction", 
      "residues", 
      "surface", 
      "lectin-ascites interaction", 
      "tumour (ascites) cell growthin vivo", 
      "cell growthin vivo", 
      "growthin vivo", 
      "Interaction andin"
    ], 
    "name": "Interaction andin vivo growth inhibition of Ehrlich ascites tumor cells by jacalin", 
    "pagination": "419-424", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1013649412"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf02703454"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf02703454", 
      "https://app.dimensions.ai/details/publication/pub.1013649412"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-11-01T17:56", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211101/entities/gbq_results/article/article_187.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/bf02703454"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf02703454'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf02703454'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf02703454'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf02703454'


 

This table displays all metadata directly associated to this object as RDF triples.

111 TRIPLES      22 PREDICATES      62 URIs      53 LITERALS      6 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf02703454 schema:about anzsrc-for:06
2 schema:author N0d060816abb44d668cd72cc863418378
3 schema:citation sg:pub.10.1007/bf01618550
4 sg:pub.10.1007/bf02702736
5 schema:datePublished 1988-12-01
6 schema:datePublishedReg 1988-12-01
7 schema:description Jacalin has been found to agglutinate Ehrlich ascites cells. The agglutination was inhibited by α-glycosides of D-Gal and β -D-Gal(1 → 3)-D-GalNAc suggesting that the lectin-ascites interaction was carbohydrate-specific. There was 21.8% inhibition of tumour (ascites) cell growthin vivo in mice administered 50μg of jacalin by injection for 6 days following intraperitoneal injection of ascites cells. Administration of 100, 150 and 200μg jacalin resulted in 40.2, 57.5 and 83% inhibition respectively. Thein vivo inhibition of tumour cells growth by jacalin was due to its preferential binding with D-Gal-α -(1 → 6) present as terminal residues in the glycoprotein on tumour cell surface.
8 schema:genre article
9 schema:inLanguage en
10 schema:isAccessibleForFree false
11 schema:isPartOf N5fbfc4971cd1495f81ae272634a09305
12 Naefc5015a5584d949cc1a544c3746b79
13 sg:journal.1092026
14 schema:keywords Ehrlich
15 Gal
16 GalNAc
17 Interaction andin
18 administration
19 agglutination
20 andin
21 ascites cells
22 binding
23 cell growth
24 cell growthin vivo
25 cell surface
26 cells
27 days
28 glycoprotein
29 glycosides
30 growth
31 growth inhibition
32 growthin vivo
33 inhibition
34 injection
35 interaction
36 intraperitoneal injection
37 jacalin
38 lectin-ascites interaction
39 mice
40 preferential binding
41 residues
42 surface
43 terminal residues
44 thein
45 tumor cell growth
46 tumor cell surface
47 tumor cells
48 tumour (ascites) cell growthin vivo
49 vivo
50 schema:name Interaction andin vivo growth inhibition of Ehrlich ascites tumor cells by jacalin
51 schema:pagination 419-424
52 schema:productId Ndb46bd43153a4239b2b614ba59cd4f21
53 Neb3a3a79d9274ad1be22389d1ca91965
54 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013649412
55 https://doi.org/10.1007/bf02703454
56 schema:sdDatePublished 2021-11-01T17:56
57 schema:sdLicense https://scigraph.springernature.com/explorer/license/
58 schema:sdPublisher Ncf0159d38f2d45aab46d12b87c9cea85
59 schema:url https://doi.org/10.1007/bf02703454
60 sgo:license sg:explorer/license/
61 sgo:sdDataset articles
62 rdf:type schema:ScholarlyArticle
63 N0d060816abb44d668cd72cc863418378 rdf:first sg:person.01322353577.23
64 rdf:rest N6952120b2c9b4b0783a70d7ee19524df
65 N26c36bbf25bf4d569b9f1b919c0ca88f schema:affiliation grid-institutes:grid.417929.0
66 schema:familyName Debnath
67 schema:givenName A. K.
68 rdf:type schema:Person
69 N5fbfc4971cd1495f81ae272634a09305 schema:issueNumber 4
70 rdf:type schema:PublicationIssue
71 N6952120b2c9b4b0783a70d7ee19524df rdf:first sg:person.01026226762.11
72 rdf:rest Nbb6500af44554b18916f2f9fb7c30162
73 Naefc5015a5584d949cc1a544c3746b79 schema:volumeNumber 13
74 rdf:type schema:PublicationVolume
75 Nbb6500af44554b18916f2f9fb7c30162 rdf:first N26c36bbf25bf4d569b9f1b919c0ca88f
76 rdf:rest rdf:nil
77 Ncf0159d38f2d45aab46d12b87c9cea85 schema:name Springer Nature - SN SciGraph project
78 rdf:type schema:Organization
79 Ndb46bd43153a4239b2b614ba59cd4f21 schema:name doi
80 schema:value 10.1007/bf02703454
81 rdf:type schema:PropertyValue
82 Neb3a3a79d9274ad1be22389d1ca91965 schema:name dimensions_id
83 schema:value pub.1013649412
84 rdf:type schema:PropertyValue
85 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
86 schema:name Biological Sciences
87 rdf:type schema:DefinedTerm
88 sg:journal.1092026 schema:issn 0253-410X
89 0973-7138
90 schema:name Journal of Biosciences
91 schema:publisher Springer Nature
92 rdf:type schema:Periodical
93 sg:person.01026226762.11 schema:affiliation grid-institutes:grid.417929.0
94 schema:familyName Chatterjee
95 schema:givenName B. P.
96 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01026226762.11
97 rdf:type schema:Person
98 sg:person.01322353577.23 schema:affiliation grid-institutes:grid.417929.0
99 schema:familyName Ahmed
100 schema:givenName H.
101 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01322353577.23
102 rdf:type schema:Person
103 sg:pub.10.1007/bf01618550 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041991745
104 https://doi.org/10.1007/bf01618550
105 rdf:type schema:CreativeWork
106 sg:pub.10.1007/bf02702736 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047326001
107 https://doi.org/10.1007/bf02702736
108 rdf:type schema:CreativeWork
109 grid-institutes:grid.417929.0 schema:alternateName Department of Biological Chemistry, Indian Association for the Cultivation of Science, Jadavpur, 700 032, Calcutta, India
110 schema:name Department of Biological Chemistry, Indian Association for the Cultivation of Science, Jadavpur, 700 032, Calcutta, India
111 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...