Die Bedeutung der Keratinozytenzüchtung für die Behandlung von Brandverletzungen View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1997-11

AUTHORS

R. Koller, Bettina Bierochs, G. S. Bayer, G. Meissl, M. Frey

ABSTRACT

Grundlagen: Die Kultivierung und anschließende Transplantation menschlicher Keratinozyten ist eine der wesentlichsten neuen Entwicklungen in der Behandlung schwerverbrannter Patienten. Methodik: Die Keratinozyten werden durch enzymatische Behandlung aus einem kleinen Hautstückchen herausgelöst und anschließend im Labor zu konfluenten Kulturen gezüchtet. Diese wiederum werden auf die debridierten Hautareale aufgebracht. Ergebnisse: Sowohl für die autologe als auch für die allogene Transplantation werden zufriedenstellende Heilungsraten publiziert. An den zu deckenden Wundgrund werden jedoch besondere Anforderungen hinsichtlich Vaskularität und Keimfreiheit gestellt. Schlußfolgerungen: Die Erfahrungen der Wiener Verbrennungsstation bestätigen die aus der Literatur bekannten Ergebnisse. Zukünftige Forschungsaktivitäten müssen einerseits trachten, rascher zur Verfügung stehende Transplantate zu entwickeln und die Anwendung als Allografts zu verbessern. More... »

PAGES

331-335

References to SciGraph publications

  • 1984-07. Loss of HLA-DR Expression by Human Epidermal Cells After Growth in Culture in JOURNAL OF INVESTIGATIVE DERMATOLOGY
  • 1982-01. Cultured Human Epidermal Cells Do Not Synthesize HLA-DR in JOURNAL OF INVESTIGATIVE DERMATOLOGY
  • Journal

    TITLE

    European Surgery

    ISSUE

    6

    VOLUME

    29

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf02619901

    DOI

    http://dx.doi.org/10.1007/bf02619901

    DIMENSIONS

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