Free radical addition of dialkyl phosphites to N,N-disubstituted amides of unsaturated fatty acids and screening of the products for antimicrobial ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1972-11

AUTHORS

R. R. Mod, J. A. Harris, J. C. Arthur, F. C. Magne, G. Sumrell, Arthur F. Novak

ABSTRACT

Free radical addition of dibutyl phosphites to terminal and internal double bonds of monounsaturated amides was attained in high yield. The reaction was initiated by irradiation using Cobalt-60. Attempts to add diphenyl phosphite to the unsaturated amides failed with the amides being recovered unchanged. Similar attempts to add dialkyl phosphites to N-linoleoylmorpholine resulted in products that were deficient in phosphorus. Screening for antimicrobial activity againstEscherichia coli, Trichosporon capitatum, Trichoderma viride andCandida lipolytica indicated that terminal addition products may be more active than the internal addition products, with the former strongly inhibiting the growth of all four test organisms. More... »

PAGES

634-635

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02609375

DOI

http://dx.doi.org/10.1007/bf02609375

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1034095302

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/5079978


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/09", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Engineering", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0904", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Chemical Engineering", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Alkylation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amides", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fatty Acids, Unsaturated", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Free Radicals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Microbial Sensitivity Tests", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Organophosphonates", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phosphorous Acids", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Structure-Activity Relationship", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Southern Regional Research Laboratory, 70179, New Orleans, Louisiana", 
          "id": "http://www.grid.ac/institutes/grid.507314.4", 
          "name": [
            "Southern Regional Research Laboratory, 70179, New Orleans, Louisiana"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mod", 
        "givenName": "R. R.", 
        "id": "sg:person.011073123343.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011073123343.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Southern Regional Research Laboratory, 70179, New Orleans, Louisiana", 
          "id": "http://www.grid.ac/institutes/grid.507314.4", 
          "name": [
            "Southern Regional Research Laboratory, 70179, New Orleans, Louisiana"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Harris", 
        "givenName": "J. A.", 
        "id": "sg:person.014135112354.64", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014135112354.64"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Southern Regional Research Laboratory, 70179, New Orleans, Louisiana", 
          "id": "http://www.grid.ac/institutes/grid.507314.4", 
          "name": [
            "Southern Regional Research Laboratory, 70179, New Orleans, Louisiana"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Arthur", 
        "givenName": "J. C.", 
        "id": "sg:person.012631527334.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012631527334.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Southern Regional Research Laboratory, 70179, New Orleans, Louisiana", 
          "id": "http://www.grid.ac/institutes/grid.507314.4", 
          "name": [
            "Southern Regional Research Laboratory, 70179, New Orleans, Louisiana"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Magne", 
        "givenName": "F. C.", 
        "id": "sg:person.012476571651.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012476571651.61"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Southern Regional Research Laboratory, 70179, New Orleans, Louisiana", 
          "id": "http://www.grid.ac/institutes/grid.507314.4", 
          "name": [
            "Southern Regional Research Laboratory, 70179, New Orleans, Louisiana"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sumrell", 
        "givenName": "G.", 
        "id": "sg:person.053045073.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.053045073.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Louisiana State University, 70803, Baton Rouge, Louisiana", 
          "id": "http://www.grid.ac/institutes/grid.64337.35", 
          "name": [
            "Louisiana State University, 70803, Baton Rouge, Louisiana"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Novak", 
        "givenName": "Arthur F.", 
        "id": "sg:person.053413502.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.053413502.25"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf02544809", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039552243", 
          "https://doi.org/10.1007/bf02544809"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf03024658", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047420749", 
          "https://doi.org/10.1007/bf03024658"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02632452", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016640224", 
          "https://doi.org/10.1007/bf02632452"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1972-11", 
    "datePublishedReg": "1972-11-01", 
    "description": "Free radical addition of dibutyl phosphites to terminal and internal double bonds of monounsaturated amides was attained in high yield. The reaction was initiated by irradiation using Cobalt-60. Attempts to add diphenyl phosphite to the unsaturated amides failed with the amides being recovered unchanged. Similar attempts to add dialkyl phosphites to N-linoleoylmorpholine resulted in products that were deficient in phosphorus. Screening for antimicrobial activity againstEscherichia coli, Trichosporon capitatum, Trichoderma viride andCandida lipolytica indicated that terminal addition products may be more active than the internal addition products, with the former strongly inhibiting the growth of all four test organisms.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/bf02609375", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1082739", 
        "issn": [
          "0003-021X", 
          "1558-9331"
        ], 
        "name": "Journal of the American Oil Chemists' Society", 
        "publisher": "Wiley", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "11", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "49"
      }
    ], 
    "keywords": [
      "high yields", 
      "antimicrobial activity", 
      "lipolytica", 
      "free radical addition", 
      "irradiation", 
      "test organisms", 
      "dialkyl phosphites", 
      "products", 
      "yield", 
      "diphenyl phosphite", 
      "similar attempts", 
      "coli", 
      "addition", 
      "reaction", 
      "againstEscherichia coli", 
      "acid", 
      "growth", 
      "screening", 
      "bonds", 
      "amides", 
      "phosphorus", 
      "organisms", 
      "activity", 
      "phosphite", 
      "cobalt-60", 
      "unsaturated fatty acids", 
      "fatty acids", 
      "radical addition", 
      "attempt", 
      "Trichosporon capitatum", 
      "double bond", 
      "unsaturated amides", 
      "internal double bonds", 
      "capitatum", 
      "addition products", 
      "dibutyl phosphite"
    ], 
    "name": "Free radical addition of dialkyl phosphites to N,N-disubstituted amides of unsaturated fatty acids and screening of the products for antimicrobial activity", 
    "pagination": "634-635", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1034095302"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf02609375"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "5079978"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf02609375", 
      "https://app.dimensions.ai/details/publication/pub.1034095302"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-09-02T15:44", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_113.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/bf02609375"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf02609375'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf02609375'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf02609375'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf02609375'


 

This table displays all metadata directly associated to this object as RDF triples.

179 TRIPLES      21 PREDICATES      73 URIs      62 LITERALS      15 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf02609375 schema:about N16db04d6848c45ed8d97141c9a4408f1
2 N2496ab6276f24f35b0973f101348155c
3 N2d3f270a24f44030939d411cd346106b
4 N4906fd67349a4d01b2142524d83a9346
5 N8dbb70683ea44b9e9da9ad4b570eb976
6 N991daa2e8dee486bbac1cf348b7f74ac
7 Nd667c40e62484c9099974ece510a71d8
8 Nec6c97df22d64078942d1cf2eeab597b
9 anzsrc-for:09
10 anzsrc-for:0904
11 schema:author N2a7e9379bb9c42d0b9ee97497f0fb1f5
12 schema:citation sg:pub.10.1007/bf02544809
13 sg:pub.10.1007/bf02632452
14 sg:pub.10.1007/bf03024658
15 schema:datePublished 1972-11
16 schema:datePublishedReg 1972-11-01
17 schema:description Free radical addition of dibutyl phosphites to terminal and internal double bonds of monounsaturated amides was attained in high yield. The reaction was initiated by irradiation using Cobalt-60. Attempts to add diphenyl phosphite to the unsaturated amides failed with the amides being recovered unchanged. Similar attempts to add dialkyl phosphites to N-linoleoylmorpholine resulted in products that were deficient in phosphorus. Screening for antimicrobial activity againstEscherichia coli, Trichosporon capitatum, Trichoderma viride andCandida lipolytica indicated that terminal addition products may be more active than the internal addition products, with the former strongly inhibiting the growth of all four test organisms.
18 schema:genre article
19 schema:isAccessibleForFree false
20 schema:isPartOf N7c9c1b0122404422868fba064371f141
21 Ne841c57a9e0046c6af7f2a946469c53e
22 sg:journal.1082739
23 schema:keywords Trichosporon capitatum
24 acid
25 activity
26 addition
27 addition products
28 againstEscherichia coli
29 amides
30 antimicrobial activity
31 attempt
32 bonds
33 capitatum
34 cobalt-60
35 coli
36 dialkyl phosphites
37 dibutyl phosphite
38 diphenyl phosphite
39 double bond
40 fatty acids
41 free radical addition
42 growth
43 high yields
44 internal double bonds
45 irradiation
46 lipolytica
47 organisms
48 phosphite
49 phosphorus
50 products
51 radical addition
52 reaction
53 screening
54 similar attempts
55 test organisms
56 unsaturated amides
57 unsaturated fatty acids
58 yield
59 schema:name Free radical addition of dialkyl phosphites to N,N-disubstituted amides of unsaturated fatty acids and screening of the products for antimicrobial activity
60 schema:pagination 634-635
61 schema:productId N615daa3ac3104c26bf1d32b47df4202f
62 N755b5834958940c197c97373a8ca63fc
63 Nf4e31e603ae648a8828494d70db731fe
64 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034095302
65 https://doi.org/10.1007/bf02609375
66 schema:sdDatePublished 2022-09-02T15:44
67 schema:sdLicense https://scigraph.springernature.com/explorer/license/
68 schema:sdPublisher Nd6bbb3b2a14a40aa9de5c7689d8f8d4c
69 schema:url https://doi.org/10.1007/bf02609375
70 sgo:license sg:explorer/license/
71 sgo:sdDataset articles
72 rdf:type schema:ScholarlyArticle
73 N16db04d6848c45ed8d97141c9a4408f1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
74 schema:name Phosphorous Acids
75 rdf:type schema:DefinedTerm
76 N2496ab6276f24f35b0973f101348155c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
77 schema:name Structure-Activity Relationship
78 rdf:type schema:DefinedTerm
79 N2a7e9379bb9c42d0b9ee97497f0fb1f5 rdf:first sg:person.011073123343.10
80 rdf:rest N4a79a422ff3a4460af22e26162c3b430
81 N2d3f270a24f44030939d411cd346106b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
82 schema:name Amides
83 rdf:type schema:DefinedTerm
84 N4906fd67349a4d01b2142524d83a9346 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Fatty Acids, Unsaturated
86 rdf:type schema:DefinedTerm
87 N4a79a422ff3a4460af22e26162c3b430 rdf:first sg:person.014135112354.64
88 rdf:rest Nc54e43fa02114559a923fc167f87cde9
89 N4bd948f2707141e893cfbbbc491d5ce4 rdf:first sg:person.053045073.19
90 rdf:rest N7dff6b069a2648508d78113cea505109
91 N615daa3ac3104c26bf1d32b47df4202f schema:name doi
92 schema:value 10.1007/bf02609375
93 rdf:type schema:PropertyValue
94 N755b5834958940c197c97373a8ca63fc schema:name dimensions_id
95 schema:value pub.1034095302
96 rdf:type schema:PropertyValue
97 N7c9c1b0122404422868fba064371f141 schema:issueNumber 11
98 rdf:type schema:PublicationIssue
99 N7dff6b069a2648508d78113cea505109 rdf:first sg:person.053413502.25
100 rdf:rest rdf:nil
101 N8dbb70683ea44b9e9da9ad4b570eb976 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Free Radicals
103 rdf:type schema:DefinedTerm
104 N991daa2e8dee486bbac1cf348b7f74ac schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Alkylation
106 rdf:type schema:DefinedTerm
107 Nc54e43fa02114559a923fc167f87cde9 rdf:first sg:person.012631527334.31
108 rdf:rest Nd87d65f165ae4b49a4d23b40bcc77d09
109 Nd667c40e62484c9099974ece510a71d8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Organophosphonates
111 rdf:type schema:DefinedTerm
112 Nd6bbb3b2a14a40aa9de5c7689d8f8d4c schema:name Springer Nature - SN SciGraph project
113 rdf:type schema:Organization
114 Nd87d65f165ae4b49a4d23b40bcc77d09 rdf:first sg:person.012476571651.61
115 rdf:rest N4bd948f2707141e893cfbbbc491d5ce4
116 Ne841c57a9e0046c6af7f2a946469c53e schema:volumeNumber 49
117 rdf:type schema:PublicationVolume
118 Nec6c97df22d64078942d1cf2eeab597b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Microbial Sensitivity Tests
120 rdf:type schema:DefinedTerm
121 Nf4e31e603ae648a8828494d70db731fe schema:name pubmed_id
122 schema:value 5079978
123 rdf:type schema:PropertyValue
124 anzsrc-for:09 schema:inDefinedTermSet anzsrc-for:
125 schema:name Engineering
126 rdf:type schema:DefinedTerm
127 anzsrc-for:0904 schema:inDefinedTermSet anzsrc-for:
128 schema:name Chemical Engineering
129 rdf:type schema:DefinedTerm
130 sg:journal.1082739 schema:issn 0003-021X
131 1558-9331
132 schema:name Journal of the American Oil Chemists' Society
133 schema:publisher Wiley
134 rdf:type schema:Periodical
135 sg:person.011073123343.10 schema:affiliation grid-institutes:grid.507314.4
136 schema:familyName Mod
137 schema:givenName R. R.
138 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011073123343.10
139 rdf:type schema:Person
140 sg:person.012476571651.61 schema:affiliation grid-institutes:grid.507314.4
141 schema:familyName Magne
142 schema:givenName F. C.
143 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012476571651.61
144 rdf:type schema:Person
145 sg:person.012631527334.31 schema:affiliation grid-institutes:grid.507314.4
146 schema:familyName Arthur
147 schema:givenName J. C.
148 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012631527334.31
149 rdf:type schema:Person
150 sg:person.014135112354.64 schema:affiliation grid-institutes:grid.507314.4
151 schema:familyName Harris
152 schema:givenName J. A.
153 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014135112354.64
154 rdf:type schema:Person
155 sg:person.053045073.19 schema:affiliation grid-institutes:grid.507314.4
156 schema:familyName Sumrell
157 schema:givenName G.
158 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.053045073.19
159 rdf:type schema:Person
160 sg:person.053413502.25 schema:affiliation grid-institutes:grid.64337.35
161 schema:familyName Novak
162 schema:givenName Arthur F.
163 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.053413502.25
164 rdf:type schema:Person
165 sg:pub.10.1007/bf02544809 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039552243
166 https://doi.org/10.1007/bf02544809
167 rdf:type schema:CreativeWork
168 sg:pub.10.1007/bf02632452 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016640224
169 https://doi.org/10.1007/bf02632452
170 rdf:type schema:CreativeWork
171 sg:pub.10.1007/bf03024658 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047420749
172 https://doi.org/10.1007/bf03024658
173 rdf:type schema:CreativeWork
174 grid-institutes:grid.507314.4 schema:alternateName Southern Regional Research Laboratory, 70179, New Orleans, Louisiana
175 schema:name Southern Regional Research Laboratory, 70179, New Orleans, Louisiana
176 rdf:type schema:Organization
177 grid-institutes:grid.64337.35 schema:alternateName Louisiana State University, 70803, Baton Rouge, Louisiana
178 schema:name Louisiana State University, 70803, Baton Rouge, Louisiana
179 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...