Transcatheter arterial infusion therapy combined with radical hysterectomy in the treatment of advanced cervical cancer View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1993-01

AUTHORS

Yasushi Nagata, Takashi Ishigaki, Kaoru Okajima, Kazuhisa Fujiwara, Tomoko Kinashi, Mitihide Mitumori, Natuo Ooya, Yosizumi Kitakabu, Masahiro Hiraoka, Mitsuyuki Abe, Kenji Takokura, Ikuo Konishi, Ichirou Takai, Shunzou Taii, Takehide Mori, S. Wallace, J. J. Kavanagh, C. H. Carrasco, Yashushi Nagata

ABSTRACT

Two or three sessions of transcatheter arterial infusion (TAI) therapy were performed preoperatively in 13 patients with advanced cervical cancer (stage 3 or more). The efficacy of TAI was evaluated by tumor markers, magnetic resonance imaging (MRI), and postoperative histopathological examination. In all cases, tumor marker levels decreased after TAI therapy, and MRI also showed a decrease in the tumor size in 11/12 patients. The tumor tissue resected at radical hysterectomy showed no viable cancer cells in 6 patients, and no viable extrauterine cancer was detected in 5 more patients. Thus, TAI performed via both internal iliac arteries reduced both tumor size and extension to the parametrium, and it appears to have the potential to be an effective treatment modality for advanced cervical cancer. More... »

PAGES

14-20

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02603031

DOI

http://dx.doi.org/10.1007/bf02603031

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1033352018

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8435830


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31 schema:description Two or three sessions of transcatheter arterial infusion (TAI) therapy were performed preoperatively in 13 patients with advanced cervical cancer (stage 3 or more). The efficacy of TAI was evaluated by tumor markers, magnetic resonance imaging (MRI), and postoperative histopathological examination. In all cases, tumor marker levels decreased after TAI therapy, and MRI also showed a decrease in the tumor size in 11/12 patients. The tumor tissue resected at radical hysterectomy showed no viable cancer cells in 6 patients, and no viable extrauterine cancer was detected in 5 more patients. Thus, TAI performed via both internal iliac arteries reduced both tumor size and extension to the parametrium, and it appears to have the potential to be an effective treatment modality for advanced cervical cancer.
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