Distribution and metabolism of hexadecylphosphocholine in mice View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1987-11

AUTHORS

A. Breiser, D. -J. Kim, E. A. M. Fleer, W. Damenz, A. drube, M. Berger, G. A. Nagel, H. Eibl, C. Unger

ABSTRACT

Distribution and metabolic fate of radiolabeled hexadecylphosphocholine (He-PC) has been studied in mice. It is demonstrated that He-PC is well-absorbed from the intestinal tract, intravenous (IV) and oral administration lead to similar distributions throughout the body, the highest accumulation of radioactivity occurs in liver, lung and kidney, and the metabolic products are radioactive choline, phosphocholine and 1,2-diacylphosphatidylcholine. The occurrence of these metabolites indicates that phospholipases C and D may be involved in He-PC breakdown. More... »

PAGES

925-926

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02535556

DOI

http://dx.doi.org/10.1007/bf02535556

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1029511128

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/3444386


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