Synergistic enhancement of the antiproliferative activity ofcis-diamminedichloroplatinum(II) by the ether lipid analogue BM41440, an inhibitor of protein kinase C View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1989-04

AUTHORS

Johann Hofmann, Florian Ueberall, Lydia Posch, Karl Maly, Dieter B. J. Herrmann, Hans Grunicke

ABSTRACT

The new phospholipid analogue 3-hexadecylmercapto-2-methoxy-methyl-propyl-1-phosphocholine inhibits the phospholipid-calcium-dependent protein kinase, partially purified from Walker carcinoma cells with a Ki value of 0.56 microM. The compound inhibits the phorbol ester stimulated phosphorylation of the ribosomal protein S6 indicating that the depression of Ca2+-phospholipid-dependent protein kinase by the alkyl phospholipid also occurs in intact cells. The dose effect curve for the inhibition of cell proliferation by 3-hexadecylmercapto-2-methoxy-methyl-propyl-1-phosphocholine in Walker cells exhibits a close correlation to the dose effect curve for the depression of Ca2+-phospholipid-dependent protein kinase activity. Although alternative mechanisms cannot be excluded, the data suggest that the growth inhibitory activity of 3-hexadecylmercapto-2-methoxy-methyl-propyl-1-phosphocholine correlates with the inhibition of Ca2+-phospholipid-dependent protein kinase. The antiproliferative activity of 3-hexadecylmercapto-2-methoxy-methyl-propyl-1-phosphocholine is synergistically enhanced by cis-diamminedichloroplatinum(II). More... »

PAGES

312-317

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02535169

DOI

http://dx.doi.org/10.1007/bf02535169

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1025303622

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2755309


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antineoplastic Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Carcinoma 256, Walker", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Division", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cisplatin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drug Synergism", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phospholipid Ethers", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phosphorylation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Kinase C", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ribosomal Protein S6", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ribosomal Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tumor Cells, Cultured", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "Institut f\u00fcr Medizinische Chemie und Biochemie, University of Innsbruck, Fritz-Pregl-Strasse 3, A-6020, Innsbruck, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hofmann", 
        "givenName": "Johann", 
        "id": "sg:person.01026373421.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01026373421.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Institut f\u00fcr Medizinische Chemie und Biochemie, University of Innsbruck, Fritz-Pregl-Strasse 3, A-6020, Innsbruck, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ueberall", 
        "givenName": "Florian", 
        "id": "sg:person.01343272273.02", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01343272273.02"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Institut f\u00fcr Medizinische Chemie und Biochemie, University of Innsbruck, Fritz-Pregl-Strasse 3, A-6020, Innsbruck, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Posch", 
        "givenName": "Lydia", 
        "id": "sg:person.01257050421.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257050421.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Institut f\u00fcr Medizinische Chemie und Biochemie, University of Innsbruck, Fritz-Pregl-Strasse 3, A-6020, Innsbruck, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Maly", 
        "givenName": "Karl", 
        "id": "sg:person.01054610636.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054610636.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Boehringer Mannheim GmbH, FRG"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Herrmann", 
        "givenName": "Dieter B. J.", 
        "id": "sg:person.01014522713.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014522713.61"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Institut f\u00fcr Medizinische Chemie und Biochemie, University of Innsbruck, Fritz-Pregl-Strasse 3, A-6020, Innsbruck, Austria"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Grunicke", 
        "givenName": "Hans", 
        "id": "sg:person.066622540.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.066622540.52"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1002/ijc.2910420313", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002413271"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/227680a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010419937", 
          "https://doi.org/10.1038/227680a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02535541", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011440683", 
          "https://doi.org/10.1007/bf02535541"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-73325-3_24", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013955329", 
          "https://doi.org/10.1007/978-3-642-73325-3_24"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-291x(87)91465-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018953068"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.2910370514", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021129821"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00410118", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024194047", 
          "https://doi.org/10.1007/bf00410118"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00410118", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024194047", 
          "https://doi.org/10.1007/bf00410118"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0065-2571(84)90007-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026371633"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0065-2571(84)90007-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026371633"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00402499", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027560770", 
          "https://doi.org/10.1007/bf00402499"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00402499", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027560770", 
          "https://doi.org/10.1007/bf00402499"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02535562", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028686569", 
          "https://doi.org/10.1007/bf02535562"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-291x(88)90592-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031166520"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0065-2571(85)90052-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040896131"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0065-2571(85)90052-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040896131"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-73325-3_21", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041848720", 
          "https://doi.org/10.1007/978-3-642-73325-3_21"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-4827(75)90325-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047656738"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-2964(80)90179-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050501128"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1981.tb06218.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052409919"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.3014651", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062582855"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.3101176", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062590839"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1358/dof.1988.013.06.66341", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1065060208"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079366723", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079494708", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079698273", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079749123", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079909309", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079935263", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080270292", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081647390", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081835456", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081903823", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081992360", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082053233", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082121534", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1989-04", 
    "datePublishedReg": "1989-04-01", 
    "description": "The new phospholipid analogue 3-hexadecylmercapto-2-methoxy-methyl-propyl-1-phosphocholine inhibits the phospholipid-calcium-dependent protein kinase, partially purified from Walker carcinoma cells with a Ki value of 0.56 microM. The compound inhibits the phorbol ester stimulated phosphorylation of the ribosomal protein S6 indicating that the depression of Ca2+-phospholipid-dependent protein kinase by the alkyl phospholipid also occurs in intact cells. The dose effect curve for the inhibition of cell proliferation by 3-hexadecylmercapto-2-methoxy-methyl-propyl-1-phosphocholine in Walker cells exhibits a close correlation to the dose effect curve for the depression of Ca2+-phospholipid-dependent protein kinase activity. Although alternative mechanisms cannot be excluded, the data suggest that the growth inhibitory activity of 3-hexadecylmercapto-2-methoxy-methyl-propyl-1-phosphocholine correlates with the inhibition of Ca2+-phospholipid-dependent protein kinase. The antiproliferative activity of 3-hexadecylmercapto-2-methoxy-methyl-propyl-1-phosphocholine is synergistically enhanced by cis-diamminedichloroplatinum(II).", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/bf02535169", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1006395", 
        "issn": [
          "0024-4201", 
          "1558-9307"
        ], 
        "name": "Lipids", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "24"
      }
    ], 
    "name": "Synergistic enhancement of the antiproliferative activity ofcis-diamminedichloroplatinum(II) by the ether lipid analogue BM41440, an inhibitor of protein kinase C", 
    "pagination": "312-317", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "788c0227ea43f3993bb913d379cdeb6365505ee0cf3639ec42313a89e585b47f"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "2755309"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0060450"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf02535169"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1025303622"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf02535169", 
      "https://app.dimensions.ai/details/publication/pub.1025303622"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T14:55", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8663_00000488.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/BF02535169"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf02535169'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf02535169'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf02535169'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf02535169'


 

This table displays all metadata directly associated to this object as RDF triples.

255 TRIPLES      21 PREDICATES      74 URIs      34 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf02535169 schema:about N1e7b35f40cd749d8a3dd0818194edeed
2 N286cf264601343a9b2523d482e460989
3 N49abdfb9eabb40d6892e1fbe67c55cab
4 N575f3e70633348d19318d45552658b01
5 N81ee56fe06664652824366c5a9faca7f
6 N930f9c5254864b20be33498411a617d2
7 Na6aa8180bb1a4b178b153d6270a076a3
8 Nb7b55ef6c75146969f4df19354109928
9 Nba4a7e8e9eb24bea901eba30fb7b802a
10 Nbb1be60fb1a94108827583e7d86d752b
11 Ne7e02b19d41e455799c50ee8c73d1c01
12 Nf78cad4584d244fca513dc3d5b132e6e
13 Nfc65dfe588fd45609367403ac3c80eb8
14 anzsrc-for:06
15 anzsrc-for:0601
16 schema:author N76fd67b9a14f4f898cc01ac2207290d4
17 schema:citation sg:pub.10.1007/978-3-642-73325-3_21
18 sg:pub.10.1007/978-3-642-73325-3_24
19 sg:pub.10.1007/bf00402499
20 sg:pub.10.1007/bf00410118
21 sg:pub.10.1007/bf02535541
22 sg:pub.10.1007/bf02535562
23 sg:pub.10.1038/227680a0
24 https://app.dimensions.ai/details/publication/pub.1079366723
25 https://app.dimensions.ai/details/publication/pub.1079494708
26 https://app.dimensions.ai/details/publication/pub.1079698273
27 https://app.dimensions.ai/details/publication/pub.1079749123
28 https://app.dimensions.ai/details/publication/pub.1079909309
29 https://app.dimensions.ai/details/publication/pub.1079935263
30 https://app.dimensions.ai/details/publication/pub.1080270292
31 https://app.dimensions.ai/details/publication/pub.1081647390
32 https://app.dimensions.ai/details/publication/pub.1081835456
33 https://app.dimensions.ai/details/publication/pub.1081903823
34 https://app.dimensions.ai/details/publication/pub.1081992360
35 https://app.dimensions.ai/details/publication/pub.1082053233
36 https://app.dimensions.ai/details/publication/pub.1082121534
37 https://doi.org/10.1002/ijc.2910370514
38 https://doi.org/10.1002/ijc.2910420313
39 https://doi.org/10.1016/0006-291x(87)91465-3
40 https://doi.org/10.1016/0006-291x(88)90592-x
41 https://doi.org/10.1016/0014-2964(80)90179-6
42 https://doi.org/10.1016/0014-4827(75)90325-0
43 https://doi.org/10.1016/0065-2571(84)90007-4
44 https://doi.org/10.1016/0065-2571(85)90052-4
45 https://doi.org/10.1111/j.1432-1033.1981.tb06218.x
46 https://doi.org/10.1126/science.3014651
47 https://doi.org/10.1126/science.3101176
48 https://doi.org/10.1358/dof.1988.013.06.66341
49 schema:datePublished 1989-04
50 schema:datePublishedReg 1989-04-01
51 schema:description The new phospholipid analogue 3-hexadecylmercapto-2-methoxy-methyl-propyl-1-phosphocholine inhibits the phospholipid-calcium-dependent protein kinase, partially purified from Walker carcinoma cells with a Ki value of 0.56 microM. The compound inhibits the phorbol ester stimulated phosphorylation of the ribosomal protein S6 indicating that the depression of Ca2+-phospholipid-dependent protein kinase by the alkyl phospholipid also occurs in intact cells. The dose effect curve for the inhibition of cell proliferation by 3-hexadecylmercapto-2-methoxy-methyl-propyl-1-phosphocholine in Walker cells exhibits a close correlation to the dose effect curve for the depression of Ca2+-phospholipid-dependent protein kinase activity. Although alternative mechanisms cannot be excluded, the data suggest that the growth inhibitory activity of 3-hexadecylmercapto-2-methoxy-methyl-propyl-1-phosphocholine correlates with the inhibition of Ca2+-phospholipid-dependent protein kinase. The antiproliferative activity of 3-hexadecylmercapto-2-methoxy-methyl-propyl-1-phosphocholine is synergistically enhanced by cis-diamminedichloroplatinum(II).
52 schema:genre research_article
53 schema:inLanguage en
54 schema:isAccessibleForFree false
55 schema:isPartOf Neb81ab1737bb489a847ba33f27e6d9cb
56 Nf0a28f6cead34fc3bdcad316763ff018
57 sg:journal.1006395
58 schema:name Synergistic enhancement of the antiproliferative activity ofcis-diamminedichloroplatinum(II) by the ether lipid analogue BM41440, an inhibitor of protein kinase C
59 schema:pagination 312-317
60 schema:productId N38b98aa3d6594748a3c02753b7fcc506
61 N3caaf5e5af3a4653a2ebf2215a930c42
62 N3ffdab493cc64895b0811350d7f3e7ed
63 N55bc01265d1f4779b4a260b3e17155fe
64 Nbfac865c4a404b4f8a0fe2ba64ff1912
65 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025303622
66 https://doi.org/10.1007/bf02535169
67 schema:sdDatePublished 2019-04-10T14:55
68 schema:sdLicense https://scigraph.springernature.com/explorer/license/
69 schema:sdPublisher N550176bafc514bd2b9328d9cdfbd178c
70 schema:url http://link.springer.com/10.1007/BF02535169
71 sgo:license sg:explorer/license/
72 sgo:sdDataset articles
73 rdf:type schema:ScholarlyArticle
74 N1e7b35f40cd749d8a3dd0818194edeed schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
75 schema:name Ribosomal Protein S6
76 rdf:type schema:DefinedTerm
77 N266441ab70f642c4b626b21a3f4563b7 schema:name Institut für Medizinische Chemie und Biochemie, University of Innsbruck, Fritz-Pregl-Strasse 3, A-6020, Innsbruck, Austria
78 rdf:type schema:Organization
79 N286cf264601343a9b2523d482e460989 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Cell Division
81 rdf:type schema:DefinedTerm
82 N38b98aa3d6594748a3c02753b7fcc506 schema:name pubmed_id
83 schema:value 2755309
84 rdf:type schema:PropertyValue
85 N3caaf5e5af3a4653a2ebf2215a930c42 schema:name readcube_id
86 schema:value 788c0227ea43f3993bb913d379cdeb6365505ee0cf3639ec42313a89e585b47f
87 rdf:type schema:PropertyValue
88 N3ffdab493cc64895b0811350d7f3e7ed schema:name nlm_unique_id
89 schema:value 0060450
90 rdf:type schema:PropertyValue
91 N483c9a7927c6466990671a1c38512920 schema:name Institut für Medizinische Chemie und Biochemie, University of Innsbruck, Fritz-Pregl-Strasse 3, A-6020, Innsbruck, Austria
92 rdf:type schema:Organization
93 N49abdfb9eabb40d6892e1fbe67c55cab schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Phosphorylation
95 rdf:type schema:DefinedTerm
96 N4af967fa113941b384f167aaf91cda69 schema:name Institut für Medizinische Chemie und Biochemie, University of Innsbruck, Fritz-Pregl-Strasse 3, A-6020, Innsbruck, Austria
97 rdf:type schema:Organization
98 N4e0512caeb8840c7911e4ec8baa5e5e6 schema:name Institut für Medizinische Chemie und Biochemie, University of Innsbruck, Fritz-Pregl-Strasse 3, A-6020, Innsbruck, Austria
99 rdf:type schema:Organization
100 N550176bafc514bd2b9328d9cdfbd178c schema:name Springer Nature - SN SciGraph project
101 rdf:type schema:Organization
102 N55bc01265d1f4779b4a260b3e17155fe schema:name dimensions_id
103 schema:value pub.1025303622
104 rdf:type schema:PropertyValue
105 N575f3e70633348d19318d45552658b01 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Ribosomal Proteins
107 rdf:type schema:DefinedTerm
108 N59e8c721c2854d408ba021d6e8cf3c50 schema:name Boehringer Mannheim GmbH, FRG
109 rdf:type schema:Organization
110 N674aa2f61a5746a789729463c27f4c4e rdf:first sg:person.01054610636.15
111 rdf:rest N9998b0b00bd74ee3afa30bfda57f81dd
112 N76fd67b9a14f4f898cc01ac2207290d4 rdf:first sg:person.01026373421.33
113 rdf:rest N9fdc5ef6cda3479e910a38d08df31898
114 N81ee56fe06664652824366c5a9faca7f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Protein Kinase C
116 rdf:type schema:DefinedTerm
117 N930f9c5254864b20be33498411a617d2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Carcinoma 256, Walker
119 rdf:type schema:DefinedTerm
120 N9998b0b00bd74ee3afa30bfda57f81dd rdf:first sg:person.01014522713.61
121 rdf:rest Ncd2f74fcfcdb4210b242aa519571493c
122 N9fdc5ef6cda3479e910a38d08df31898 rdf:first sg:person.01343272273.02
123 rdf:rest Ne39ba830259744e08d247eb8a1ea2132
124 Na6aa8180bb1a4b178b153d6270a076a3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Animals
126 rdf:type schema:DefinedTerm
127 Nb7b55ef6c75146969f4df19354109928 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Antineoplastic Agents
129 rdf:type schema:DefinedTerm
130 Nba4a7e8e9eb24bea901eba30fb7b802a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Cisplatin
132 rdf:type schema:DefinedTerm
133 Nbb1be60fb1a94108827583e7d86d752b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Drug Synergism
135 rdf:type schema:DefinedTerm
136 Nbfac865c4a404b4f8a0fe2ba64ff1912 schema:name doi
137 schema:value 10.1007/bf02535169
138 rdf:type schema:PropertyValue
139 Ncd2f74fcfcdb4210b242aa519571493c rdf:first sg:person.066622540.52
140 rdf:rest rdf:nil
141 Ne39ba830259744e08d247eb8a1ea2132 rdf:first sg:person.01257050421.71
142 rdf:rest N674aa2f61a5746a789729463c27f4c4e
143 Ne7e02b19d41e455799c50ee8c73d1c01 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Phospholipid Ethers
145 rdf:type schema:DefinedTerm
146 Neb81ab1737bb489a847ba33f27e6d9cb schema:issueNumber 4
147 rdf:type schema:PublicationIssue
148 Nf0a28f6cead34fc3bdcad316763ff018 schema:volumeNumber 24
149 rdf:type schema:PublicationVolume
150 Nf78cad4584d244fca513dc3d5b132e6e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Rats
152 rdf:type schema:DefinedTerm
153 Nfad14a6e55924495b8e51de94f5353bc schema:name Institut für Medizinische Chemie und Biochemie, University of Innsbruck, Fritz-Pregl-Strasse 3, A-6020, Innsbruck, Austria
154 rdf:type schema:Organization
155 Nfc65dfe588fd45609367403ac3c80eb8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Tumor Cells, Cultured
157 rdf:type schema:DefinedTerm
158 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
159 schema:name Biological Sciences
160 rdf:type schema:DefinedTerm
161 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
162 schema:name Biochemistry and Cell Biology
163 rdf:type schema:DefinedTerm
164 sg:journal.1006395 schema:issn 0024-4201
165 1558-9307
166 schema:name Lipids
167 rdf:type schema:Periodical
168 sg:person.01014522713.61 schema:affiliation N59e8c721c2854d408ba021d6e8cf3c50
169 schema:familyName Herrmann
170 schema:givenName Dieter B. J.
171 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014522713.61
172 rdf:type schema:Person
173 sg:person.01026373421.33 schema:affiliation N266441ab70f642c4b626b21a3f4563b7
174 schema:familyName Hofmann
175 schema:givenName Johann
176 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01026373421.33
177 rdf:type schema:Person
178 sg:person.01054610636.15 schema:affiliation N4e0512caeb8840c7911e4ec8baa5e5e6
179 schema:familyName Maly
180 schema:givenName Karl
181 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054610636.15
182 rdf:type schema:Person
183 sg:person.01257050421.71 schema:affiliation N483c9a7927c6466990671a1c38512920
184 schema:familyName Posch
185 schema:givenName Lydia
186 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01257050421.71
187 rdf:type schema:Person
188 sg:person.01343272273.02 schema:affiliation N4af967fa113941b384f167aaf91cda69
189 schema:familyName Ueberall
190 schema:givenName Florian
191 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01343272273.02
192 rdf:type schema:Person
193 sg:person.066622540.52 schema:affiliation Nfad14a6e55924495b8e51de94f5353bc
194 schema:familyName Grunicke
195 schema:givenName Hans
196 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.066622540.52
197 rdf:type schema:Person
198 sg:pub.10.1007/978-3-642-73325-3_21 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041848720
199 https://doi.org/10.1007/978-3-642-73325-3_21
200 rdf:type schema:CreativeWork
201 sg:pub.10.1007/978-3-642-73325-3_24 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013955329
202 https://doi.org/10.1007/978-3-642-73325-3_24
203 rdf:type schema:CreativeWork
204 sg:pub.10.1007/bf00402499 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027560770
205 https://doi.org/10.1007/bf00402499
206 rdf:type schema:CreativeWork
207 sg:pub.10.1007/bf00410118 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024194047
208 https://doi.org/10.1007/bf00410118
209 rdf:type schema:CreativeWork
210 sg:pub.10.1007/bf02535541 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011440683
211 https://doi.org/10.1007/bf02535541
212 rdf:type schema:CreativeWork
213 sg:pub.10.1007/bf02535562 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028686569
214 https://doi.org/10.1007/bf02535562
215 rdf:type schema:CreativeWork
216 sg:pub.10.1038/227680a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010419937
217 https://doi.org/10.1038/227680a0
218 rdf:type schema:CreativeWork
219 https://app.dimensions.ai/details/publication/pub.1079366723 schema:CreativeWork
220 https://app.dimensions.ai/details/publication/pub.1079494708 schema:CreativeWork
221 https://app.dimensions.ai/details/publication/pub.1079698273 schema:CreativeWork
222 https://app.dimensions.ai/details/publication/pub.1079749123 schema:CreativeWork
223 https://app.dimensions.ai/details/publication/pub.1079909309 schema:CreativeWork
224 https://app.dimensions.ai/details/publication/pub.1079935263 schema:CreativeWork
225 https://app.dimensions.ai/details/publication/pub.1080270292 schema:CreativeWork
226 https://app.dimensions.ai/details/publication/pub.1081647390 schema:CreativeWork
227 https://app.dimensions.ai/details/publication/pub.1081835456 schema:CreativeWork
228 https://app.dimensions.ai/details/publication/pub.1081903823 schema:CreativeWork
229 https://app.dimensions.ai/details/publication/pub.1081992360 schema:CreativeWork
230 https://app.dimensions.ai/details/publication/pub.1082053233 schema:CreativeWork
231 https://app.dimensions.ai/details/publication/pub.1082121534 schema:CreativeWork
232 https://doi.org/10.1002/ijc.2910370514 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021129821
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1002/ijc.2910420313 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002413271
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1016/0006-291x(87)91465-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018953068
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1016/0006-291x(88)90592-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1031166520
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1016/0014-2964(80)90179-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050501128
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1016/0014-4827(75)90325-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047656738
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1016/0065-2571(84)90007-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026371633
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1016/0065-2571(85)90052-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040896131
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1111/j.1432-1033.1981.tb06218.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1052409919
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1126/science.3014651 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062582855
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1126/science.3101176 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062590839
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1358/dof.1988.013.06.66341 schema:sameAs https://app.dimensions.ai/details/publication/pub.1065060208
255 rdf:type schema:CreativeWork
 




Preview window. Press ESC to close (or click here)


...