Thyroid hormone is required for dietary fish oil to induce hypersecretion of biliary cholesterol in the rat View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1995-09

AUTHORS

William F. Prigge, Scott R. Ketover, Roger L. Gebhard

ABSTRACT

In the rat, both fish oil diet and thyroid hormone replacement are reported to augment bile cholesterol secretion out of proportion to bile flow or secretion of other bile lipids. We sought common mechanisms for these effects and evaluated the role of phospholipid fatty acid composition in the process. Methimazole-treated hypothyroid rats were fed low-fat chow or chow supplemented with 10% corn oil or fish oil, and were studied before and after thyroid hormone treatment. Serum, hepatic, and bile lipids were measured, phospholipid fatty acid composition determined, and hepatic 3-hydroxy-3-methylglutaryl CoA reductase activity assayed. Fish oil diet stimulated cholesterol secretion into bile only after thyroid hormone was given, and this action was synergistic with that of thyroid hormone. Reduced serum cholesterol in fish oil-treated rats was associated with increased biliary cholesterol secretion and diminished hepatic cholesterol content. This suggests that augmented biliary cholesterol secretion may contribute to the fish oil-induced reduction of serum cholesterol. No definite relationship between hepatic or biliary phospholipid fatty acid composition and biliary secretion was apparent, although high bile cholesterol secretion was associated with a low percentage of hepatic and bile phospholipid linoleic acid. More... »

PAGES

833-838

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02533959

DOI

http://dx.doi.org/10.1007/bf02533959

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1046614695

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8577227


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antithyroid Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bile", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cholesterol", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dietary Fats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drug Synergism", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Fish Oils", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hydroxymethylglutaryl CoA Reductases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Liver", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Methimazole", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phospholipids", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats, Sprague-Dawley", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Thyroid Hormones", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Minnesota", 
          "id": "https://www.grid.ac/institutes/grid.17635.36", 
          "name": [
            "Research Service (151) Department of Medicine, VA Medical Center, One Veterans Drive, 55417, Minneapolis, Minnesota", 
            "University of Minnesota, 55455, Minneapolis, Minnesota"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Prigge", 
        "givenName": "William F.", 
        "id": "sg:person.0721004503.26", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721004503.26"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Minnesota", 
          "id": "https://www.grid.ac/institutes/grid.17635.36", 
          "name": [
            "Research Service (151) Department of Medicine, VA Medical Center, One Veterans Drive, 55417, Minneapolis, Minnesota", 
            "University of Minnesota, 55455, Minneapolis, Minnesota"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ketover", 
        "givenName": "Scott R.", 
        "id": "sg:person.01302077542.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302077542.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Minnesota", 
          "id": "https://www.grid.ac/institutes/grid.17635.36", 
          "name": [
            "Research Service (151) Department of Medicine, VA Medical Center, One Veterans Drive, 55417, Minneapolis, Minnesota", 
            "University of Minnesota, 55455, Minneapolis, Minnesota"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gebhard", 
        "givenName": "Roger L.", 
        "id": "sg:person.0652671303.82", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0652671303.82"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1172/jci109024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006093752"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj2070029", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006160995"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj2070029", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006160995"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci115397", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010552277"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02536158", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012910251", 
          "https://doi.org/10.1007/bf02536158"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0026-0495(83)90226-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014685651"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2362.1991.tb01369.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015343983"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.atv.4.3.270", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019633483"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/9780470110249.ch3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020474766"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2362.1983.tb00071.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020555073"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.1840140417", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021127856"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0168-8278(92)90012-e", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026603836"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/hep.1840160418", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030641370"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02562424", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032302387", 
          "https://doi.org/10.1007/bf02562424"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm198505093121902", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033311314"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci111422", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034222037"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/b978-0-12-718051-9.50006-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035069708"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci116666", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039052845"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2760(90)90092-c", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042129322"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2760(90)90092-c", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042129322"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci108299", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043900342"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02534904", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045959629", 
          "https://doi.org/10.1007/bf02534904"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1930845", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053136185"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1930845", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053136185"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0270-9139(91)90057-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054555681"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/endo-125-1-459", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064262525"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076420223", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076420233", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076604793", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076750128", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078385252", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080091309", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/ajpregu.1979.236.3.r175", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1080233420"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081003191", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082148426", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082597487", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082683844", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082794728", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1995-09", 
    "datePublishedReg": "1995-09-01", 
    "description": "In the rat, both fish oil diet and thyroid hormone replacement are reported to augment bile cholesterol secretion out of proportion to bile flow or secretion of other bile lipids. We sought common mechanisms for these effects and evaluated the role of phospholipid fatty acid composition in the process. Methimazole-treated hypothyroid rats were fed low-fat chow or chow supplemented with 10% corn oil or fish oil, and were studied before and after thyroid hormone treatment. Serum, hepatic, and bile lipids were measured, phospholipid fatty acid composition determined, and hepatic 3-hydroxy-3-methylglutaryl CoA reductase activity assayed. Fish oil diet stimulated cholesterol secretion into bile only after thyroid hormone was given, and this action was synergistic with that of thyroid hormone. Reduced serum cholesterol in fish oil-treated rats was associated with increased biliary cholesterol secretion and diminished hepatic cholesterol content. This suggests that augmented biliary cholesterol secretion may contribute to the fish oil-induced reduction of serum cholesterol. No definite relationship between hepatic or biliary phospholipid fatty acid composition and biliary secretion was apparent, although high bile cholesterol secretion was associated with a low percentage of hepatic and bile phospholipid linoleic acid.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/bf02533959", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1006395", 
        "issn": [
          "0024-4201", 
          "1558-9307"
        ], 
        "name": "Lipids", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "9", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "30"
      }
    ], 
    "name": "Thyroid hormone is required for dietary fish oil to induce hypersecretion of biliary cholesterol in the rat", 
    "pagination": "833-838", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "de0dfb9d3f147753958ff45ab28442ae6a5d38eb362390da4d03d20e4aebb9fb"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "8577227"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0060450"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf02533959"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1046614695"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf02533959", 
      "https://app.dimensions.ai/details/publication/pub.1046614695"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T17:25", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8672_00000483.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/BF02533959"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf02533959'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf02533959'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf02533959'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf02533959'


 

This table displays all metadata directly associated to this object as RDF triples.

241 TRIPLES      21 PREDICATES      79 URIs      36 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf02533959 schema:about N0238b71bc88e48fb9f0a2c1eb632e7e0
2 N1387ccfb20bc47e4a289925a96d2e2b3
3 N24988647c4eb4f48a3e8e16d21feffe5
4 N2d6da454e3dd4766a3e5958bcfe1e47b
5 N34c409af9bdb484cb10c5052490470b5
6 N3a67018564aa41a0ba9bd17cca2d2ef0
7 N3f9590cbaa5a4b94b34d30fddcf856bc
8 N70ada1bf3ea34e1596a05ccc907659bf
9 N72366badcdb9485f8e081c70f4ae678a
10 N746e377b823947ed945ae91c7c467ee8
11 N769f50e6978a45b1a68ec2d90c077934
12 N79cbf3685f054e5fa07b73341dbad3e1
13 Na3b524cab26c4a55bfd97b373b58b589
14 Nc2a43fe1a049416b803f7fcc9245ab2a
15 Ndc29031de55849f4adf3b433e00b711d
16 anzsrc-for:11
17 anzsrc-for:1103
18 schema:author Nebca34756b804e2c9ab315c3c4cd18cc
19 schema:citation sg:pub.10.1007/bf02534904
20 sg:pub.10.1007/bf02536158
21 sg:pub.10.1007/bf02562424
22 https://app.dimensions.ai/details/publication/pub.1076420223
23 https://app.dimensions.ai/details/publication/pub.1076420233
24 https://app.dimensions.ai/details/publication/pub.1076604793
25 https://app.dimensions.ai/details/publication/pub.1076750128
26 https://app.dimensions.ai/details/publication/pub.1078385252
27 https://app.dimensions.ai/details/publication/pub.1080091309
28 https://app.dimensions.ai/details/publication/pub.1081003191
29 https://app.dimensions.ai/details/publication/pub.1082148426
30 https://app.dimensions.ai/details/publication/pub.1082597487
31 https://app.dimensions.ai/details/publication/pub.1082683844
32 https://app.dimensions.ai/details/publication/pub.1082794728
33 https://doi.org/10.1002/9780470110249.ch3
34 https://doi.org/10.1002/hep.1840140417
35 https://doi.org/10.1002/hep.1840160418
36 https://doi.org/10.1016/0005-2760(90)90092-c
37 https://doi.org/10.1016/0026-0495(83)90226-3
38 https://doi.org/10.1016/0168-8278(92)90012-e
39 https://doi.org/10.1016/0270-9139(91)90057-3
40 https://doi.org/10.1016/b978-0-12-718051-9.50006-8
41 https://doi.org/10.1042/bj1930845
42 https://doi.org/10.1042/bj2070029
43 https://doi.org/10.1056/nejm198505093121902
44 https://doi.org/10.1111/j.1365-2362.1983.tb00071.x
45 https://doi.org/10.1111/j.1365-2362.1991.tb01369.x
46 https://doi.org/10.1152/ajpregu.1979.236.3.r175
47 https://doi.org/10.1161/01.atv.4.3.270
48 https://doi.org/10.1172/jci108299
49 https://doi.org/10.1172/jci109024
50 https://doi.org/10.1172/jci111422
51 https://doi.org/10.1172/jci115397
52 https://doi.org/10.1172/jci116666
53 https://doi.org/10.1210/endo-125-1-459
54 schema:datePublished 1995-09
55 schema:datePublishedReg 1995-09-01
56 schema:description In the rat, both fish oil diet and thyroid hormone replacement are reported to augment bile cholesterol secretion out of proportion to bile flow or secretion of other bile lipids. We sought common mechanisms for these effects and evaluated the role of phospholipid fatty acid composition in the process. Methimazole-treated hypothyroid rats were fed low-fat chow or chow supplemented with 10% corn oil or fish oil, and were studied before and after thyroid hormone treatment. Serum, hepatic, and bile lipids were measured, phospholipid fatty acid composition determined, and hepatic 3-hydroxy-3-methylglutaryl CoA reductase activity assayed. Fish oil diet stimulated cholesterol secretion into bile only after thyroid hormone was given, and this action was synergistic with that of thyroid hormone. Reduced serum cholesterol in fish oil-treated rats was associated with increased biliary cholesterol secretion and diminished hepatic cholesterol content. This suggests that augmented biliary cholesterol secretion may contribute to the fish oil-induced reduction of serum cholesterol. No definite relationship between hepatic or biliary phospholipid fatty acid composition and biliary secretion was apparent, although high bile cholesterol secretion was associated with a low percentage of hepatic and bile phospholipid linoleic acid.
57 schema:genre research_article
58 schema:inLanguage en
59 schema:isAccessibleForFree false
60 schema:isPartOf N4a1d9335afe84234880ed3643f3ac564
61 Nc066ddd7d8194acb8399f3b6f635428a
62 sg:journal.1006395
63 schema:name Thyroid hormone is required for dietary fish oil to induce hypersecretion of biliary cholesterol in the rat
64 schema:pagination 833-838
65 schema:productId N2c36e113b4234a3d90295a1eea2c1add
66 N68c1419e7587470f817631e09db1215a
67 N851953d00b6944c5a8758c08383c88cb
68 Nae9e207e1bf240198029ce862407aec7
69 Ncb05634529a94cd68995c6e07e01bc49
70 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046614695
71 https://doi.org/10.1007/bf02533959
72 schema:sdDatePublished 2019-04-10T17:25
73 schema:sdLicense https://scigraph.springernature.com/explorer/license/
74 schema:sdPublisher N6f418207a8094b4c8492f6831b69d8f9
75 schema:url http://link.springer.com/10.1007/BF02533959
76 sgo:license sg:explorer/license/
77 sgo:sdDataset articles
78 rdf:type schema:ScholarlyArticle
79 N0238b71bc88e48fb9f0a2c1eb632e7e0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Liver
81 rdf:type schema:DefinedTerm
82 N1387ccfb20bc47e4a289925a96d2e2b3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Thyroid Hormones
84 rdf:type schema:DefinedTerm
85 N2055b5b2e6d247c291a097e3f0813191 rdf:first sg:person.01302077542.97
86 rdf:rest Nd55d36f8bc154b1b83ef8302363a06d4
87 N24988647c4eb4f48a3e8e16d21feffe5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Antithyroid Agents
89 rdf:type schema:DefinedTerm
90 N2c36e113b4234a3d90295a1eea2c1add schema:name readcube_id
91 schema:value de0dfb9d3f147753958ff45ab28442ae6a5d38eb362390da4d03d20e4aebb9fb
92 rdf:type schema:PropertyValue
93 N2d6da454e3dd4766a3e5958bcfe1e47b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Dietary Fats
95 rdf:type schema:DefinedTerm
96 N34c409af9bdb484cb10c5052490470b5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Methimazole
98 rdf:type schema:DefinedTerm
99 N3a67018564aa41a0ba9bd17cca2d2ef0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Rats, Sprague-Dawley
101 rdf:type schema:DefinedTerm
102 N3f9590cbaa5a4b94b34d30fddcf856bc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Drug Synergism
104 rdf:type schema:DefinedTerm
105 N4a1d9335afe84234880ed3643f3ac564 schema:volumeNumber 30
106 rdf:type schema:PublicationVolume
107 N68c1419e7587470f817631e09db1215a schema:name dimensions_id
108 schema:value pub.1046614695
109 rdf:type schema:PropertyValue
110 N6f418207a8094b4c8492f6831b69d8f9 schema:name Springer Nature - SN SciGraph project
111 rdf:type schema:Organization
112 N70ada1bf3ea34e1596a05ccc907659bf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Animals
114 rdf:type schema:DefinedTerm
115 N72366badcdb9485f8e081c70f4ae678a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Male
117 rdf:type schema:DefinedTerm
118 N746e377b823947ed945ae91c7c467ee8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Bile
120 rdf:type schema:DefinedTerm
121 N769f50e6978a45b1a68ec2d90c077934 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Hydroxymethylglutaryl CoA Reductases
123 rdf:type schema:DefinedTerm
124 N79cbf3685f054e5fa07b73341dbad3e1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Phospholipids
126 rdf:type schema:DefinedTerm
127 N851953d00b6944c5a8758c08383c88cb schema:name nlm_unique_id
128 schema:value 0060450
129 rdf:type schema:PropertyValue
130 Na3b524cab26c4a55bfd97b373b58b589 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Cholesterol
132 rdf:type schema:DefinedTerm
133 Nae9e207e1bf240198029ce862407aec7 schema:name pubmed_id
134 schema:value 8577227
135 rdf:type schema:PropertyValue
136 Nc066ddd7d8194acb8399f3b6f635428a schema:issueNumber 9
137 rdf:type schema:PublicationIssue
138 Nc2a43fe1a049416b803f7fcc9245ab2a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Rats
140 rdf:type schema:DefinedTerm
141 Ncb05634529a94cd68995c6e07e01bc49 schema:name doi
142 schema:value 10.1007/bf02533959
143 rdf:type schema:PropertyValue
144 Nd55d36f8bc154b1b83ef8302363a06d4 rdf:first sg:person.0652671303.82
145 rdf:rest rdf:nil
146 Ndc29031de55849f4adf3b433e00b711d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Fish Oils
148 rdf:type schema:DefinedTerm
149 Nebca34756b804e2c9ab315c3c4cd18cc rdf:first sg:person.0721004503.26
150 rdf:rest N2055b5b2e6d247c291a097e3f0813191
151 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
152 schema:name Medical and Health Sciences
153 rdf:type schema:DefinedTerm
154 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
155 schema:name Clinical Sciences
156 rdf:type schema:DefinedTerm
157 sg:journal.1006395 schema:issn 0024-4201
158 1558-9307
159 schema:name Lipids
160 rdf:type schema:Periodical
161 sg:person.01302077542.97 schema:affiliation https://www.grid.ac/institutes/grid.17635.36
162 schema:familyName Ketover
163 schema:givenName Scott R.
164 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01302077542.97
165 rdf:type schema:Person
166 sg:person.0652671303.82 schema:affiliation https://www.grid.ac/institutes/grid.17635.36
167 schema:familyName Gebhard
168 schema:givenName Roger L.
169 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0652671303.82
170 rdf:type schema:Person
171 sg:person.0721004503.26 schema:affiliation https://www.grid.ac/institutes/grid.17635.36
172 schema:familyName Prigge
173 schema:givenName William F.
174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721004503.26
175 rdf:type schema:Person
176 sg:pub.10.1007/bf02534904 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045959629
177 https://doi.org/10.1007/bf02534904
178 rdf:type schema:CreativeWork
179 sg:pub.10.1007/bf02536158 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012910251
180 https://doi.org/10.1007/bf02536158
181 rdf:type schema:CreativeWork
182 sg:pub.10.1007/bf02562424 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032302387
183 https://doi.org/10.1007/bf02562424
184 rdf:type schema:CreativeWork
185 https://app.dimensions.ai/details/publication/pub.1076420223 schema:CreativeWork
186 https://app.dimensions.ai/details/publication/pub.1076420233 schema:CreativeWork
187 https://app.dimensions.ai/details/publication/pub.1076604793 schema:CreativeWork
188 https://app.dimensions.ai/details/publication/pub.1076750128 schema:CreativeWork
189 https://app.dimensions.ai/details/publication/pub.1078385252 schema:CreativeWork
190 https://app.dimensions.ai/details/publication/pub.1080091309 schema:CreativeWork
191 https://app.dimensions.ai/details/publication/pub.1081003191 schema:CreativeWork
192 https://app.dimensions.ai/details/publication/pub.1082148426 schema:CreativeWork
193 https://app.dimensions.ai/details/publication/pub.1082597487 schema:CreativeWork
194 https://app.dimensions.ai/details/publication/pub.1082683844 schema:CreativeWork
195 https://app.dimensions.ai/details/publication/pub.1082794728 schema:CreativeWork
196 https://doi.org/10.1002/9780470110249.ch3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020474766
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1002/hep.1840140417 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021127856
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1002/hep.1840160418 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030641370
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1016/0005-2760(90)90092-c schema:sameAs https://app.dimensions.ai/details/publication/pub.1042129322
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1016/0026-0495(83)90226-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014685651
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1016/0168-8278(92)90012-e schema:sameAs https://app.dimensions.ai/details/publication/pub.1026603836
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1016/0270-9139(91)90057-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054555681
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1016/b978-0-12-718051-9.50006-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035069708
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1042/bj1930845 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053136185
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1042/bj2070029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006160995
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1056/nejm198505093121902 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033311314
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1111/j.1365-2362.1983.tb00071.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1020555073
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1111/j.1365-2362.1991.tb01369.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1015343983
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1152/ajpregu.1979.236.3.r175 schema:sameAs https://app.dimensions.ai/details/publication/pub.1080233420
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1161/01.atv.4.3.270 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019633483
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1172/jci108299 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043900342
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1172/jci109024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006093752
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1172/jci111422 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034222037
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1172/jci115397 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010552277
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1172/jci116666 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039052845
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1210/endo-125-1-459 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064262525
237 rdf:type schema:CreativeWork
238 https://www.grid.ac/institutes/grid.17635.36 schema:alternateName University of Minnesota
239 schema:name Research Service (151) Department of Medicine, VA Medical Center, One Veterans Drive, 55417, Minneapolis, Minnesota
240 University of Minnesota, 55455, Minneapolis, Minnesota
241 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...