Ontology type: schema:ScholarlyArticle
1998-01
AUTHORSE. P. Serebryakov, A. G. Nigmatov, M. A. Shcherbakov, M. I. Struchkova
ABSTRACTIn the amine-catalyzed reactions of prenal with (Z)-5-methyl-2-(methoxycarbonyl)hexa-2,4-dienoic or (Z)-3-phenyl-2-(ethoxycarbonyl)prop-2-enoic acid chiral β-amino alcohols provide for higher enantiomeric purity of the resulting alkyl 4-methyl-6-(2-methylprop-1-enyl)-and 4-methyl-6-phenylcyclohexa-1,3-dienoates than that provided by related chiral amines without hydroxy group. The values ofee attained in nonpolar solvents are higher than those observed in the polar ones. Substituting stoichiometric amounts of a chiral 1-amino-3-methylbuta-1,3-diene for a combination of prenal with 0.1 equiv. of the corresponding chiral amine results in the products of much lower enantiomeric purity. More... »
PAGES82
http://scigraph.springernature.com/pub.10.1007/bf02495513
DOIhttp://dx.doi.org/10.1007/bf02495513
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