Malignant transformation of meningeal melanocytoma: A case report View Full Text


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Article Info

DATE

2003-03

AUTHORS

Yoichi Uozumi, Teruaki Kawano, Tsutomu Kawaguchi, Yoshirou Kaneko, Takao Ooasa, Sadanobu Ogasawara, Hidenori Yoshida, Takahisa Yoshida

ABSTRACT

Intracranial meningeal melanocytoma is an uncommon tumor that is considered benign. We formerly reported an intracranial meningeal melanocytoma. Here we report a extremely rare case of malignant transformation of this tumor. A 49-year-old man complained of a headache. Magnetic resonance scanning revealed a mass in the left frontal region. The patient underwent gross total removal of the tomor in 1994. The histological findings showed a meningeal melanocytoma. In 1998, he underwent γ-knife surgery for local recurrence. An additional operation was performed in 1999 became tumor growth was not stopped. The tumor was partially excised by left frontal craniotomy. Histopathological examination revealed a malignant melanoma originating from a melanocytoma. The tumor was composed of a proliferation of severely atypical melanocytoid cells with slightly irregular nuclei and prominent nucleoli, associated with necrosis and hemorrhage. Mitotic figures were encountered occasionally. After six months, he died from cerebrospinal fluid dissemination of this tumor. To our knowledge, this is the first report of malignant transformation of an intracranial meningeal melanocytoma. More... »

PAGES

21-25

References to SciGraph publications

  • 1989-07. Malignant transformation of an iris melanocytoma in GRAEFE'S ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
  • 2000-01. Radiosurgery of Meningeal Melanocytoma in JOURNAL OF NEURO-ONCOLOGY
  • 1998-07. Unusual Clinical Presentation of a Meningeal Melanocytoma with Seizures: Case Report and Review of the Literature in ACTA NEUROCHIRURGICA
  • 1988-03. Meningeal melanocytoma in ACTA NEUROCHIRURGICA
  • 1997-11. Intracranial meningeal melanocytoma: CT and MRI in NEURORADIOLOGY
  • 1998-03. Meningeal melanocytoma in the left frontal region in BRAIN TUMOR PATHOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf02478943

    DOI

    http://dx.doi.org/10.1007/bf02478943

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1046527862

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/14604228


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