A note on the quantum-theoretic basis of primary genetic activity View Full Text


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Article Info

DATE

1963-06

AUTHORS

Robert Rosen

ABSTRACT

In previous work (Bull. Math. Biophysics,23, 393–403, 1960) it was shown that, if primary genetic processes are of an essentially microphysical nature, the objects bearing the primary genetic information must act in a catalytic fashion. At the same time it was pointed out that the kind of catalysis involved in the primary genetic process was fundamentally different, in specific ways, from that occurring, e.g., in enzyme systems. The present work demonstrates that, if the information-bearing objects of the general theory are identified with molecules of DNA, and the primary gene products are considered to be RNA of the “messenger” variety, then the predictions of the general theory can be compared with experimental data from various recently isolated polymerase systems, which appear to “copy” a sequence of nucleotides from DNA into RNAin vitro, and with certainin vivo microbial systems. It is found that these data provide detailed support for the conclusions drawn from the general theory. However, it is emphasized that the identification of the information-bearing objects and primary gene products as DNA and RNA respectively, which allows us to compare the theory with the cited data, is by no means the only identification which can be made; i.e., other interpretations of the general theory are certainly not precluded. More... »

PAGES

183-187

References to SciGraph publications

  • 1960-09. A quantum-theoretic approach to genetic problems in BULLETIN OF MATHEMATICAL BIOLOGY
  • 1961-12. On the role of chemical systems in the microphysical aspects of primary genetic mechanisms in BULLETIN OF MATHEMATICAL BIOLOGY
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    http://scigraph.springernature.com/pub.10.1007/bf02478276

    DOI

    http://dx.doi.org/10.1007/bf02478276

    DIMENSIONS

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    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/13974852


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