Zinc in clinical surgery —A research review— View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1990-11

AUTHORS

Okada Akira, Takagi Yoji, Nezu Riichiro, Lee Shoko

ABSTRACT

Among the essential trace elements in mammals, zinc is somewhat unique in that it is a constituent of numerous metallo-enzymes having biologic significance in many respects. The discovery of zinc deficiency in man induced the remarkable progress of studies on its physiology and it is now recognized that zinc deficiency manifests itself differently in different areas of clinical medicine. It also appears reasonable to say that no trace elements have been more closely related to surgery than zinc. We discuss herein, its significance, implications and role in such areas as; (1) wound healing: where the usefulness of zinc for promoting wound healing in the presence of low plasma zinc levels has been firmly established; (2) total parenteral nutrition (TPN): zinc free TPN may cause skin eruptions associated with abdominal symptoms presenting a picture closely resembling that of acrodermatitis enteropathica; (3) specific pathological conditions: patients with Crohn's disease and other benign diseases accompanied by mal-digestion or-absorbtion are often predisposed to zinc deficiency, similar to those manifesting clinical signs in the early stage of TPN; and (4) surgical stress: which triggers the release of various mediators, possibly increasing hepatic zinc deposition and decreasing plasma and skin zinc levels. More... »

PAGES

635-644

References to SciGraph publications

  • 1976-12. An importance of zinc in total parenteral nutrition in THE JAPANESE JOURNAL OF SURGERY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf02471026

    DOI

    http://dx.doi.org/10.1007/bf02471026

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1053744427

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/2128093


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Clinical Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Parenteral Nutrition, Total", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Stress, Physiological", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Surgical Procedures, Operative", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Wound Healing", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Zinc", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "The Department of Pediatric Surgery, Osaka University Medical School, 1-1-50, Fukushima, Fukushima-ku, 553, Osaka, Japan", 
              "id": "http://www.grid.ac/institutes/grid.136593.b", 
              "name": [
                "The Department of Pediatric Surgery, Osaka University Medical School, 1-1-50, Fukushima, Fukushima-ku, 553, Osaka, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Akira", 
            "givenName": "Okada", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "The Department of Pediatric Surgery, Osaka University Medical School, 1-1-50, Fukushima, Fukushima-ku, 553, Osaka, Japan", 
              "id": "http://www.grid.ac/institutes/grid.136593.b", 
              "name": [
                "The Department of Pediatric Surgery, Osaka University Medical School, 1-1-50, Fukushima, Fukushima-ku, 553, Osaka, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Yoji", 
            "givenName": "Takagi", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "The Department of Pediatric Surgery, Osaka University Medical School, 1-1-50, Fukushima, Fukushima-ku, 553, Osaka, Japan", 
              "id": "http://www.grid.ac/institutes/grid.136593.b", 
              "name": [
                "The Department of Pediatric Surgery, Osaka University Medical School, 1-1-50, Fukushima, Fukushima-ku, 553, Osaka, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Riichiro", 
            "givenName": "Nezu", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "The Department of Pediatric Surgery, Osaka University Medical School, 1-1-50, Fukushima, Fukushima-ku, 553, Osaka, Japan", 
              "id": "http://www.grid.ac/institutes/grid.136593.b", 
              "name": [
                "The Department of Pediatric Surgery, Osaka University Medical School, 1-1-50, Fukushima, Fukushima-ku, 553, Osaka, Japan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Shoko", 
            "givenName": "Lee", 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1007/bf02468991", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037723695", 
              "https://doi.org/10.1007/bf02468991"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "1990-11", 
        "datePublishedReg": "1990-11-01", 
        "description": "Among the essential trace elements in mammals, zinc is somewhat unique in that it is a constituent of numerous metallo-enzymes having biologic significance in many respects. The discovery of zinc deficiency in man induced the remarkable progress of studies on its physiology and it is now recognized that zinc deficiency manifests itself differently in different areas of clinical medicine. It also appears reasonable to say that no trace elements have been more closely related to surgery than zinc. We discuss herein, its significance, implications and role in such areas as; (1) wound healing: where the usefulness of zinc for promoting wound healing in the presence of low plasma zinc levels has been firmly established; (2) total parenteral nutrition (TPN): zinc free TPN may cause skin eruptions associated with abdominal symptoms presenting a picture closely resembling that of acrodermatitis enteropathica; (3) specific pathological conditions: patients with Crohn's disease and other benign diseases accompanied by mal-digestion or-absorbtion are often predisposed to zinc deficiency, similar to those manifesting clinical signs in the early stage of TPN; and (4) surgical stress: which triggers the release of various mediators, possibly increasing hepatic zinc deposition and decreasing plasma and skin zinc levels.", 
        "genre": "article", 
        "id": "sg:pub.10.1007/bf02471026", 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1055369", 
            "issn": [
              "0047-1909"
            ], 
            "name": "The Japanese Journal of Surgery", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "6", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "20"
          }
        ], 
        "keywords": [
          "total parenteral nutrition", 
          "zinc levels", 
          "low plasma zinc levels", 
          "zinc deficiency", 
          "plasma zinc levels", 
          "abdominal symptoms", 
          "surgical stress", 
          "parenteral nutrition", 
          "skin eruption", 
          "Crohn's disease", 
          "specific pathological conditions", 
          "benign disease", 
          "clinical signs", 
          "acrodermatitis enteropathica", 
          "biologic significance", 
          "pathological conditions", 
          "disease", 
          "wound healing", 
          "surgery", 
          "clinical surgery", 
          "essential trace element", 
          "clinical medicine", 
          "deficiency", 
          "healing", 
          "early stages", 
          "patients", 
          "symptoms", 
          "men", 
          "levels", 
          "mediators", 
          "significance", 
          "nutrition", 
          "signs", 
          "remarkable progress", 
          "medicine", 
          "review", 
          "physiology", 
          "release", 
          "zinc", 
          "plasma", 
          "study", 
          "research review", 
          "role", 
          "usefulness", 
          "different areas", 
          "area", 
          "presence", 
          "eruption", 
          "stage", 
          "mammals", 
          "stress", 
          "trace elements", 
          "discovery", 
          "implications", 
          "constituents", 
          "progress", 
          "picture", 
          "absorbtion", 
          "such areas", 
          "conditions", 
          "respect", 
          "deposition", 
          "elements", 
          "zinc deposition"
        ], 
        "name": "Zinc in clinical surgery \u2014A research review\u2014", 
        "pagination": "635-644", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1053744427"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/bf02471026"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "2128093"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/bf02471026", 
          "https://app.dimensions.ai/details/publication/pub.1053744427"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-10-01T06:29", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20221001/entities/gbq_results/article/article_239.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1007/bf02471026"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf02471026'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf02471026'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf02471026'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf02471026'


     

    This table displays all metadata directly associated to this object as RDF triples.

    169 TRIPLES      21 PREDICATES      97 URIs      88 LITERALS      13 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/bf02471026 schema:about N06dd35485f1c4cc6a3e41c7ea45b29e3
    2 N42ffce37d3d74f9b85b8dc97db74c4ed
    3 N5324183827774646b83103be5e4325fe
    4 N91595fdbef004e43a344d73e62b2a28d
    5 Ne534c0583b584be38e2cf2e7a2aef151
    6 Nf4a29468834c450d985b04496506c9ea
    7 anzsrc-for:11
    8 anzsrc-for:1103
    9 schema:author Nb309bba646d04edb949fc40e59e5b83e
    10 schema:citation sg:pub.10.1007/bf02468991
    11 schema:datePublished 1990-11
    12 schema:datePublishedReg 1990-11-01
    13 schema:description Among the essential trace elements in mammals, zinc is somewhat unique in that it is a constituent of numerous metallo-enzymes having biologic significance in many respects. The discovery of zinc deficiency in man induced the remarkable progress of studies on its physiology and it is now recognized that zinc deficiency manifests itself differently in different areas of clinical medicine. It also appears reasonable to say that no trace elements have been more closely related to surgery than zinc. We discuss herein, its significance, implications and role in such areas as; (1) wound healing: where the usefulness of zinc for promoting wound healing in the presence of low plasma zinc levels has been firmly established; (2) total parenteral nutrition (TPN): zinc free TPN may cause skin eruptions associated with abdominal symptoms presenting a picture closely resembling that of acrodermatitis enteropathica; (3) specific pathological conditions: patients with Crohn's disease and other benign diseases accompanied by mal-digestion or-absorbtion are often predisposed to zinc deficiency, similar to those manifesting clinical signs in the early stage of TPN; and (4) surgical stress: which triggers the release of various mediators, possibly increasing hepatic zinc deposition and decreasing plasma and skin zinc levels.
    14 schema:genre article
    15 schema:isAccessibleForFree false
    16 schema:isPartOf N800dad40eeaf436faa84d7f7e9f5e598
    17 Nf3030b8539b94a50bc05be102aae6904
    18 sg:journal.1055369
    19 schema:keywords Crohn's disease
    20 abdominal symptoms
    21 absorbtion
    22 acrodermatitis enteropathica
    23 area
    24 benign disease
    25 biologic significance
    26 clinical medicine
    27 clinical signs
    28 clinical surgery
    29 conditions
    30 constituents
    31 deficiency
    32 deposition
    33 different areas
    34 discovery
    35 disease
    36 early stages
    37 elements
    38 eruption
    39 essential trace element
    40 healing
    41 implications
    42 levels
    43 low plasma zinc levels
    44 mammals
    45 mediators
    46 medicine
    47 men
    48 nutrition
    49 parenteral nutrition
    50 pathological conditions
    51 patients
    52 physiology
    53 picture
    54 plasma
    55 plasma zinc levels
    56 presence
    57 progress
    58 release
    59 remarkable progress
    60 research review
    61 respect
    62 review
    63 role
    64 significance
    65 signs
    66 skin eruption
    67 specific pathological conditions
    68 stage
    69 stress
    70 study
    71 such areas
    72 surgery
    73 surgical stress
    74 symptoms
    75 total parenteral nutrition
    76 trace elements
    77 usefulness
    78 wound healing
    79 zinc
    80 zinc deficiency
    81 zinc deposition
    82 zinc levels
    83 schema:name Zinc in clinical surgery —A research review—
    84 schema:pagination 635-644
    85 schema:productId N17fea5c964f14013b3c2fd491a6d7b18
    86 N31922cbafc5c4ae5a3bbf55190f83fc7
    87 Need43deba919448d8eafa6d65fd2968c
    88 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053744427
    89 https://doi.org/10.1007/bf02471026
    90 schema:sdDatePublished 2022-10-01T06:29
    91 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    92 schema:sdPublisher N0856923f945f4d658bd3de55d7b610f8
    93 schema:url https://doi.org/10.1007/bf02471026
    94 sgo:license sg:explorer/license/
    95 sgo:sdDataset articles
    96 rdf:type schema:ScholarlyArticle
    97 N06dd35485f1c4cc6a3e41c7ea45b29e3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    98 schema:name Surgical Procedures, Operative
    99 rdf:type schema:DefinedTerm
    100 N0856923f945f4d658bd3de55d7b610f8 schema:name Springer Nature - SN SciGraph project
    101 rdf:type schema:Organization
    102 N17fea5c964f14013b3c2fd491a6d7b18 schema:name dimensions_id
    103 schema:value pub.1053744427
    104 rdf:type schema:PropertyValue
    105 N31922cbafc5c4ae5a3bbf55190f83fc7 schema:name pubmed_id
    106 schema:value 2128093
    107 rdf:type schema:PropertyValue
    108 N42ffce37d3d74f9b85b8dc97db74c4ed schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    109 schema:name Zinc
    110 rdf:type schema:DefinedTerm
    111 N46d673b43c774acca5fd49c1658da57e rdf:first N95c5d12487b54a19b3d97a8b3c563fa6
    112 rdf:rest Nc2c63c2b6ccc4af489b0e1c65de17bd3
    113 N4b2e9a4790404e80bd51ee5f08392379 rdf:first N5cfa1239621c4a3da50201a07db97f8a
    114 rdf:rest rdf:nil
    115 N5324183827774646b83103be5e4325fe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    116 schema:name Stress, Physiological
    117 rdf:type schema:DefinedTerm
    118 N5cfa1239621c4a3da50201a07db97f8a schema:affiliation grid-institutes:grid.136593.b
    119 schema:familyName Shoko
    120 schema:givenName Lee
    121 rdf:type schema:Person
    122 N800dad40eeaf436faa84d7f7e9f5e598 schema:issueNumber 6
    123 rdf:type schema:PublicationIssue
    124 N91595fdbef004e43a344d73e62b2a28d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    125 schema:name Parenteral Nutrition, Total
    126 rdf:type schema:DefinedTerm
    127 N95c5d12487b54a19b3d97a8b3c563fa6 schema:affiliation grid-institutes:grid.136593.b
    128 schema:familyName Yoji
    129 schema:givenName Takagi
    130 rdf:type schema:Person
    131 N96cf6d0c7e3e4bfe9f1edbe9065ca5a9 schema:affiliation grid-institutes:grid.136593.b
    132 schema:familyName Akira
    133 schema:givenName Okada
    134 rdf:type schema:Person
    135 Nb309bba646d04edb949fc40e59e5b83e rdf:first N96cf6d0c7e3e4bfe9f1edbe9065ca5a9
    136 rdf:rest N46d673b43c774acca5fd49c1658da57e
    137 Nba1718032a53405f80c4e2853f65a0a4 schema:affiliation grid-institutes:grid.136593.b
    138 schema:familyName Riichiro
    139 schema:givenName Nezu
    140 rdf:type schema:Person
    141 Nc2c63c2b6ccc4af489b0e1c65de17bd3 rdf:first Nba1718032a53405f80c4e2853f65a0a4
    142 rdf:rest N4b2e9a4790404e80bd51ee5f08392379
    143 Ne534c0583b584be38e2cf2e7a2aef151 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    144 schema:name Humans
    145 rdf:type schema:DefinedTerm
    146 Need43deba919448d8eafa6d65fd2968c schema:name doi
    147 schema:value 10.1007/bf02471026
    148 rdf:type schema:PropertyValue
    149 Nf3030b8539b94a50bc05be102aae6904 schema:volumeNumber 20
    150 rdf:type schema:PublicationVolume
    151 Nf4a29468834c450d985b04496506c9ea schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    152 schema:name Wound Healing
    153 rdf:type schema:DefinedTerm
    154 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    155 schema:name Medical and Health Sciences
    156 rdf:type schema:DefinedTerm
    157 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
    158 schema:name Clinical Sciences
    159 rdf:type schema:DefinedTerm
    160 sg:journal.1055369 schema:issn 0047-1909
    161 schema:name The Japanese Journal of Surgery
    162 schema:publisher Springer Nature
    163 rdf:type schema:Periodical
    164 sg:pub.10.1007/bf02468991 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037723695
    165 https://doi.org/10.1007/bf02468991
    166 rdf:type schema:CreativeWork
    167 grid-institutes:grid.136593.b schema:alternateName The Department of Pediatric Surgery, Osaka University Medical School, 1-1-50, Fukushima, Fukushima-ku, 553, Osaka, Japan
    168 schema:name The Department of Pediatric Surgery, Osaka University Medical School, 1-1-50, Fukushima, Fukushima-ku, 553, Osaka, Japan
    169 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...