Ca2+-dependent 4-aminopyridine- and α-latrotoxin-evoked [14C] GABA release has different sensitivity to protein kinase inhibitors View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1998-07

AUTHORS

L. G. Storchak, N. G. Pozdniakova, N. H. Himmelreich

ABSTRACT

Synaptosomes from the rat brain were used to study the influence of protein kinase inhibitors on the plasma membrane calcium permeability and calcium-dependent α-latrotoxin (LTX)-induced [14C] GABA release. It was shown that stimulated by depolarization with 4-aminopyridine (4-AP) calcium permeability was inhibited by sphingosine. Calcium permeability evoked by LTX was insensitive to either of following agents; sphingosine, staurosporine, and W-7. Unlike pronounced inhibitory effects of sphingosine, staurosporine, or W-7 on 4-AP-evoked [15C] GABA release, a calcium-dependent secretagogue effect of LTX was not changed by these agents. The mechanism of clacium-dependent LTX-evoked secretagogue effect is discussed. More... »

PAGES

238-241

Journal

TITLE

Neurophysiology

ISSUE

4-5

VOLUME

30

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02462827

DOI

http://dx.doi.org/10.1007/bf02462827

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1042194116


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Palladin Institute of Biochemistry", 
          "id": "https://www.grid.ac/institutes/grid.419966.5", 
          "name": [
            "Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Storchak", 
        "givenName": "L. G.", 
        "id": "sg:person.015254252667.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015254252667.00"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Palladin Institute of Biochemistry", 
          "id": "https://www.grid.ac/institutes/grid.419966.5", 
          "name": [
            "Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pozdniakova", 
        "givenName": "N. G.", 
        "id": "sg:person.013505160011.92", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013505160011.92"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Palladin Institute of Biochemistry", 
          "id": "https://www.grid.ac/institutes/grid.419966.5", 
          "name": [
            "Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Himmelreich", 
        "givenName": "N. H.", 
        "id": "sg:person.01016527735.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01016527735.99"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1074/jbc.272.34.21504", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016657334"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.81.2.620", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024515827"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0896-6273(00)80332-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028585141"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0076-6879(74)31050-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030573040"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0306-4522(97)00599-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040264968"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1621094", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062496028"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.8430330", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062655570"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078833699", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082397280", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1523/jneurosci.18-08-02914.1998", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083236472"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1998-07", 
    "datePublishedReg": "1998-07-01", 
    "description": "Synaptosomes from the rat brain were used to study the influence of protein kinase inhibitors on the plasma membrane calcium permeability and calcium-dependent \u03b1-latrotoxin (LTX)-induced [14C] GABA release. It was shown that stimulated by depolarization with 4-aminopyridine (4-AP) calcium permeability was inhibited by sphingosine. Calcium permeability evoked by LTX was insensitive to either of following agents; sphingosine, staurosporine, and W-7. Unlike pronounced inhibitory effects of sphingosine, staurosporine, or W-7 on 4-AP-evoked [15C] GABA release, a calcium-dependent secretagogue effect of LTX was not changed by these agents. The mechanism of clacium-dependent LTX-evoked secretagogue effect is discussed.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/bf02462827", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1016854", 
        "issn": [
          "0090-2977", 
          "1573-9007"
        ], 
        "name": "Neurophysiology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4-5", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "30"
      }
    ], 
    "name": "Ca2+-dependent 4-aminopyridine- and \u03b1-latrotoxin-evoked [14C] GABA release has different sensitivity to protein kinase inhibitors", 
    "pagination": "238-241", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "c8fdedb41fdbfce4b5697c42cb4d6a8b8f88880278d3d7c27228aadb1e2a2b8c"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf02462827"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1042194116"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf02462827", 
      "https://app.dimensions.ai/details/publication/pub.1042194116"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T13:36", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000370_0000000370/records_46777_00000002.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/BF02462827"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf02462827'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf02462827'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf02462827'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf02462827'


 

This table displays all metadata directly associated to this object as RDF triples.

103 TRIPLES      21 PREDICATES      37 URIs      19 LITERALS      7 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf02462827 schema:about anzsrc-for:11
2 anzsrc-for:1109
3 schema:author N342ab45fe8134cb5a8b7a196b6a7cd11
4 schema:citation https://app.dimensions.ai/details/publication/pub.1078833699
5 https://app.dimensions.ai/details/publication/pub.1082397280
6 https://doi.org/10.1016/0076-6879(74)31050-6
7 https://doi.org/10.1016/s0306-4522(97)00599-x
8 https://doi.org/10.1016/s0896-6273(00)80332-3
9 https://doi.org/10.1073/pnas.81.2.620
10 https://doi.org/10.1074/jbc.272.34.21504
11 https://doi.org/10.1126/science.1621094
12 https://doi.org/10.1126/science.8430330
13 https://doi.org/10.1523/jneurosci.18-08-02914.1998
14 schema:datePublished 1998-07
15 schema:datePublishedReg 1998-07-01
16 schema:description Synaptosomes from the rat brain were used to study the influence of protein kinase inhibitors on the plasma membrane calcium permeability and calcium-dependent α-latrotoxin (LTX)-induced [14C] GABA release. It was shown that stimulated by depolarization with 4-aminopyridine (4-AP) calcium permeability was inhibited by sphingosine. Calcium permeability evoked by LTX was insensitive to either of following agents; sphingosine, staurosporine, and W-7. Unlike pronounced inhibitory effects of sphingosine, staurosporine, or W-7 on 4-AP-evoked [15C] GABA release, a calcium-dependent secretagogue effect of LTX was not changed by these agents. The mechanism of clacium-dependent LTX-evoked secretagogue effect is discussed.
17 schema:genre research_article
18 schema:inLanguage en
19 schema:isAccessibleForFree false
20 schema:isPartOf N24740cae64694648a92ac2d9cee6f8c4
21 N63df7c07067446b1a1bba7748061018b
22 sg:journal.1016854
23 schema:name Ca2+-dependent 4-aminopyridine- and α-latrotoxin-evoked [14C] GABA release has different sensitivity to protein kinase inhibitors
24 schema:pagination 238-241
25 schema:productId N2c6cc3e63319482eb22d66f85c1853a1
26 N9a4682a632b245baa61027a7ba03aa7e
27 Nfe20ee91ec1b4905b36ce85b226ee6e6
28 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042194116
29 https://doi.org/10.1007/bf02462827
30 schema:sdDatePublished 2019-04-11T13:36
31 schema:sdLicense https://scigraph.springernature.com/explorer/license/
32 schema:sdPublisher Nc9e858ea48f74230bf44812c5393906f
33 schema:url http://link.springer.com/10.1007/BF02462827
34 sgo:license sg:explorer/license/
35 sgo:sdDataset articles
36 rdf:type schema:ScholarlyArticle
37 N24740cae64694648a92ac2d9cee6f8c4 schema:issueNumber 4-5
38 rdf:type schema:PublicationIssue
39 N2c6cc3e63319482eb22d66f85c1853a1 schema:name readcube_id
40 schema:value c8fdedb41fdbfce4b5697c42cb4d6a8b8f88880278d3d7c27228aadb1e2a2b8c
41 rdf:type schema:PropertyValue
42 N342ab45fe8134cb5a8b7a196b6a7cd11 rdf:first sg:person.015254252667.00
43 rdf:rest N470fd662f0e14e3f889d08bc73f5dea0
44 N470fd662f0e14e3f889d08bc73f5dea0 rdf:first sg:person.013505160011.92
45 rdf:rest Nc516c37284e345c6b48e9e075f9cd247
46 N63df7c07067446b1a1bba7748061018b schema:volumeNumber 30
47 rdf:type schema:PublicationVolume
48 N9a4682a632b245baa61027a7ba03aa7e schema:name doi
49 schema:value 10.1007/bf02462827
50 rdf:type schema:PropertyValue
51 Nc516c37284e345c6b48e9e075f9cd247 rdf:first sg:person.01016527735.99
52 rdf:rest rdf:nil
53 Nc9e858ea48f74230bf44812c5393906f schema:name Springer Nature - SN SciGraph project
54 rdf:type schema:Organization
55 Nfe20ee91ec1b4905b36ce85b226ee6e6 schema:name dimensions_id
56 schema:value pub.1042194116
57 rdf:type schema:PropertyValue
58 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
59 schema:name Medical and Health Sciences
60 rdf:type schema:DefinedTerm
61 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
62 schema:name Neurosciences
63 rdf:type schema:DefinedTerm
64 sg:journal.1016854 schema:issn 0090-2977
65 1573-9007
66 schema:name Neurophysiology
67 rdf:type schema:Periodical
68 sg:person.01016527735.99 schema:affiliation https://www.grid.ac/institutes/grid.419966.5
69 schema:familyName Himmelreich
70 schema:givenName N. H.
71 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01016527735.99
72 rdf:type schema:Person
73 sg:person.013505160011.92 schema:affiliation https://www.grid.ac/institutes/grid.419966.5
74 schema:familyName Pozdniakova
75 schema:givenName N. G.
76 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013505160011.92
77 rdf:type schema:Person
78 sg:person.015254252667.00 schema:affiliation https://www.grid.ac/institutes/grid.419966.5
79 schema:familyName Storchak
80 schema:givenName L. G.
81 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015254252667.00
82 rdf:type schema:Person
83 https://app.dimensions.ai/details/publication/pub.1078833699 schema:CreativeWork
84 https://app.dimensions.ai/details/publication/pub.1082397280 schema:CreativeWork
85 https://doi.org/10.1016/0076-6879(74)31050-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030573040
86 rdf:type schema:CreativeWork
87 https://doi.org/10.1016/s0306-4522(97)00599-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1040264968
88 rdf:type schema:CreativeWork
89 https://doi.org/10.1016/s0896-6273(00)80332-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028585141
90 rdf:type schema:CreativeWork
91 https://doi.org/10.1073/pnas.81.2.620 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024515827
92 rdf:type schema:CreativeWork
93 https://doi.org/10.1074/jbc.272.34.21504 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016657334
94 rdf:type schema:CreativeWork
95 https://doi.org/10.1126/science.1621094 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062496028
96 rdf:type schema:CreativeWork
97 https://doi.org/10.1126/science.8430330 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062655570
98 rdf:type schema:CreativeWork
99 https://doi.org/10.1523/jneurosci.18-08-02914.1998 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083236472
100 rdf:type schema:CreativeWork
101 https://www.grid.ac/institutes/grid.419966.5 schema:alternateName Palladin Institute of Biochemistry
102 schema:name Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv, Ukraine
103 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...