Effect of radiation on the functioning of neuron chromatin of mice exposed in the zone of the Chernobyl nuclear power ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1996-05

AUTHORS

A. G. Mustafin, V. N. Yarygin, N. M. Vakhtel', L. V. Bibaeva

ABSTRACT

Circadian fluctuations in the activity of endogenous RNA polymerases were examined in the nuclei ofLv spinal ganglion neurocytes, spinal α-motoneurons, and in neurons of the sensorimotor and visual cortex of mice exposed to radiation in the zone of the Chernobyl power plant. The circadian organization of the functioning of the genetic apparatus of neurons in various compartments of the nervous system was altered in irradiated mice. A shift of the acrophases of nucleoplasmic and nucleolar labeling in the course of the 24-hour cycle was observed after a 40-day exposure under conditions of a high radioactive background. The degree of synchronization of the level of transcription of ribosomal and structural genes of the studied cell populations diminished. The mesors and amplitudes of circadian rhythms of chromatin matrix activity decreased. The status of the histone component of chromatin also changed in exposed animals. More... »

PAGES

500-503

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02446950

DOI

http://dx.doi.org/10.1007/bf02446950

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1031378982


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