Immunochemical analysis of common antigenic determinants in insulin and apoprotein B Molecules View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1994-09

AUTHORS

L. E. Panin, L. S. Ostanina, N. V. Atuchina

ABSTRACT

A study is performed of the mechanism underlying stress diabetes, which develops in human beings and animals under stress. Dot-immunoanalysis shows the presence of common antigenic determinants in insulin, apoprotein B, and apoprotein B-containing low density and very low density lipoproteins isolated from human and rat serum. Electrophoresis, immunoelectroblotting, and immunoenzyme analysis reveal 5–6 peptides belonging to apoB, which specifically react with anti-insulin and anti-very low density lipoprotein antibodies. Insulinlike immunoreactivity is also identified in human serum supernatant obtained after precipitation of the total low density and very low density lipoprotein fraction and after removal all lipoproteins from it. More... »

PAGES

956-959

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02445783

DOI

http://dx.doi.org/10.1007/bf02445783

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1031105963


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