Auxiliary liver transplantation in patients with fulminant hepatic failure: Hepatobiliary scintigraphic follow-up View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1997-02

AUTHORS

Dominique Buyck, François Bonnin, Jacques Bernuau, Jacques Belghiti, Bernard Bok

ABSTRACT

Auxiliary liver transplantation (ALT), retaining in place the liver of the recipient, has been proposed as an alternative to liver replacement in patients with fulminant hepatic failure (FHF). Hepatobiliary scintigraphy (HS) has proved a unique tool for the separate assessment of graft and native liver function. Forty-eight HS scans were performed, following the injection of technetium-99m trimethyl-bromo-imino-diacetic acid, in six patients who underwent ALT for FHF. Quantitative parameters were derived from the time-activity curves of both the graft and the native liver. The function of the graft remained normal as long as the patients remained under immunosuppressive therapy (IST). The function of the native liver was almost completely absent in the 1st month in five patients, but it improved gradually in four of them. IST was then decreased in four patients and finally withdrawn in three. Spontaneous graft atrophy occurred in two patients and the graft was removed in two. All of the patients in whom IST was reduced had a normal global hepatic function and selective uptake (RU) >30% at that time. In ALT patients with FHF, HS can distinguish non-invasively the functional performance of both the donor and the recipient liver and its evolution with time. More... »

PAGES

138-142

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02439545

DOI

http://dx.doi.org/10.1007/bf02439545

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1018040791

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/9021110


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204 grid-institutes:grid.411599.1 schema:alternateName Department of Hepatology, Hôpital Beaujon, Clichy, France
205 Department of Nuclear Medicine, Hôpital Beaujon, Clichy, France
206 Department of Surgery, Hôpital Beaujon, Clichy, France
207 schema:name Department of Hepatology, Hôpital Beaujon, Clichy, France
208 Department of Nuclear Medicine, Hôpital Beaujon, Clichy, France
209 Department of Surgery, Hôpital Beaujon, Clichy, France
210 rdf:type schema:Organization
 




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