Effect of isosmotic medium with low sodium content on mitochondria of cultured cerebellar granular cells View Full Text


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Article Info

DATE

2000-01

AUTHORS

E. V. Stel'mashuk, N. K. Isaev, O. P. Aleksandrova, N. A. Andreeva, D. B. Zorov, I. V. Viktorov

ABSTRACT

Experiments with rhodamine-123 showed that incubation of cultured cerebellar granular cells in a medium with NaCl isosmotically replaced with sucrose reduced mitochondrial membrane potential. Elimination of Ca2+ or addition of CoCl2, noncompetitive (MK-801) and competitive (APH) N-methyl-D-aspartate receptor antagonists abolished deenergizing effects of low-sodium solutions.

PAGES

33-35

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02433861

DOI

http://dx.doi.org/10.1007/bf02433861

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1015634331


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