Effects of antioxidant butylated hydroxytoluene (BHT) on hormonal regulation and ESR signals in adult and old rats View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1990-01

AUTHORS

Vladimir V. Frolkis, Evgeny N. Gorban, Vitaly K. Koltover

ABSTRACT

The effects of a single administration of BHT on the intensity of ESR signals in blood plasma, as well as on the plasma concentrations of ACTH, 11-OHCS, TSH and T3 hormones within 48 hours following the drug administration were studied in the experiments on adult (4–6 months) and old (24–26 months) male Wistar rats. Changes due to BHT took place in the intensity of ESR transferrin and ceruloplasmin signals in the blood. There were also significant BHT-induced changes in the plasma concentrations of ACTH, 11-OHCS, TSH and T3 hormones. The amplitude and the direction of the changes depended upon the type of hormones, the time period that had elapsed after BHT injection, and the animal’s age. Thus, the physiological effects of BHT in vivo seem to be mediated via the system of the organism’s neurohumoral regulation. More... »

PAGES

5-8

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02432501

DOI

http://dx.doi.org/10.1007/bf02432501

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1053012755


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