Haemolytic disease of the newborn infant. Long term efficiency of the screening and the prevention of alloimmunization in the mother: ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1991-04

AUTHORS

P. Moncharmont, F. Juron Dupraz, M. Vignal, D. Rigal, F. Meyer, P. Debeaux

ABSTRACT

During the last thirty years, the diagnosis, management and prevention of haemolytic disease of the newborn infant (HDN) have improved. From 1959 to 1988, 3004 HDN (ABO excluded) have been collected. The percentage of HDN with anti-D alloimmunization decreased significantly (98.4% from 1959 to 1968, 93.5% from 1969 to 1978 and 68.1% from 1979 to 1988). The anti-D HDN with exchange transfusion (ET) fell significantly between the first and second periods (577 versus 970;X2=19.92;P<0.001). On the other hand, the number of HDN other than anti-D increased during these three periods, but the percentage of these HDN which needed ET decreased. Our study shows the long term efficiency of the prevention of anti-D alloimmunization (since 1970) and of the irregular antibodies screening among all pregnant women (since 1979). More... »

PAGES

175-180

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02390356

DOI

http://dx.doi.org/10.1007/bf02390356

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1012661601

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/1910321


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