Abnormal neuropeptide concentration in rectal mucosa of patients with inflammatory bowel disease View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1996-08

AUTHORS

Hitoshi Yamamoto, Kimitomo Morise, Kazuo Kusugami, Atsushi Furusawa, Toshihiro Konagaya, Yuji Nishio, Hiroshi Kaneko, Kiyoshi Uchida, Hirofumi Nagai, Terunori Mitsuma, Hiroshi Nagura

ABSTRACT

Regulatory neuropeptides are widely distributed in the gastrointestinal tract, where they play an important role in motility, secretion, and immune and inflammatory responses. In this study, the rectal mucosal content of somatostatin (SOM), substance P (SP), beta-endorphin (BE), and thyrotropin-releasing hormone (TRH) was measured by radioimmunoassay in 56 patients with ulcerative colitis (UC), 15 patients with Crohn's disease (CD), 15 patients with acute infectious colitis (AIC), and 11 controls, who showed no inflammation of the rectal mucosa, nor abnormal bowel movements. The content of immunoreactive (ir)-SOM was decreased in UC patients, especially in those with persistent disease activity, while the levels of ir-SP, BE, and TRH were increased in such patients. Some changes of ir-peptide levels were also observed in CD and AIC patients. The changes in neuropeptide levels were analyzed in relation to histological grades of inflammation in UC patients, grades 4-5 showing the most significant changes. The levels of ir-SOM, SP, BE, and TRH showed no significant change in chronic persistent UC when measured 6-12 months after the initial examination. In contrast, in patients with remitting intermittent UC, the levels of SP and BE decreased during remission. Abnormal intestinal neuropeptide content may be implicated in the continued mucosal immune and inflammatory responses that are manifested in patients with inflammatory bowel disease. More... »

PAGES

525-532

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02355052

DOI

http://dx.doi.org/10.1007/bf02355052

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1000853070

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8844473


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Immunology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biopsy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Case-Control Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Colonoscopy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Inflammatory Bowel Diseases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Intestinal Mucosa", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neuropeptides", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Radioimmunoassay", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rectum", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Nagoya University", 
          "id": "https://www.grid.ac/institutes/grid.27476.30", 
          "name": [
            "First Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-ku, 466, Nagoya, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yamamoto", 
        "givenName": "Hitoshi", 
        "id": "sg:person.01173353312.53", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01173353312.53"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagoya University", 
          "id": "https://www.grid.ac/institutes/grid.27476.30", 
          "name": [
            "First Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-ku, 466, Nagoya, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Morise", 
        "givenName": "Kimitomo", 
        "id": "sg:person.0607317206.74", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0607317206.74"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagoya University", 
          "id": "https://www.grid.ac/institutes/grid.27476.30", 
          "name": [
            "First Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-ku, 466, Nagoya, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kusugami", 
        "givenName": "Kazuo", 
        "id": "sg:person.01162701441.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162701441.28"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagoya University", 
          "id": "https://www.grid.ac/institutes/grid.27476.30", 
          "name": [
            "First Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-ku, 466, Nagoya, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Furusawa", 
        "givenName": "Atsushi", 
        "id": "sg:person.01300651260.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01300651260.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagoya University", 
          "id": "https://www.grid.ac/institutes/grid.27476.30", 
          "name": [
            "First Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-ku, 466, Nagoya, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Konagaya", 
        "givenName": "Toshihiro", 
        "id": "sg:person.01225060647.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01225060647.95"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nagoya University", 
          "id": "https://www.grid.ac/institutes/grid.27476.30", 
          "name": [
            "First Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-ku, 466, Nagoya, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nishio", 
        "givenName": "Yuji", 
        "id": "sg:person.01110442572.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01110442572.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Aichi Medical University", 
          "id": "https://www.grid.ac/institutes/grid.411234.1", 
          "name": [
            "Fourth Department of Internal Medicine, Aichi Medical University, 21 Yazako-karimata, Nagakute-cho, 480-11, Aichi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kaneko", 
        "givenName": "Hiroshi", 
        "id": "sg:person.012571543577.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012571543577.39"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Aichi Medical University", 
          "id": "https://www.grid.ac/institutes/grid.411234.1", 
          "name": [
            "Fourth Department of Internal Medicine, Aichi Medical University, 21 Yazako-karimata, Nagakute-cho, 480-11, Aichi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Uchida", 
        "givenName": "Kiyoshi", 
        "id": "sg:person.0631204540.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631204540.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Aichi Medical University", 
          "id": "https://www.grid.ac/institutes/grid.411234.1", 
          "name": [
            "Fourth Department of Internal Medicine, Aichi Medical University, 21 Yazako-karimata, Nagakute-cho, 480-11, Aichi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nagai", 
        "givenName": "Hirofumi", 
        "id": "sg:person.01013546340.06", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01013546340.06"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Aichi Medical University", 
          "id": "https://www.grid.ac/institutes/grid.411234.1", 
          "name": [
            "Fourth Department of Internal Medicine, Aichi Medical University, 21 Yazako-karimata, Nagakute-cho, 480-11, Aichi, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mitsuma", 
        "givenName": "Terunori", 
        "id": "sg:person.01112026626.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112026626.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Tohoku University", 
          "id": "https://www.grid.ac/institutes/grid.69566.3a", 
          "name": [
            "Department of Pathology, Tohoku University of Medicine, 2-1 Seiryo-machi, Aoba-ku, 980, Sendai, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nagura", 
        "givenName": "Hiroshi", 
        "id": "sg:person.0723362470.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0723362470.15"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf02552546", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000883767", 
          "https://doi.org/10.1007/bf02552546"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1007/bf02552546", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000883767"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-0115(93)90040-f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002850195"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1530/acta.0.0830225", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003123947"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.2.4947.1041", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004911330"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-291x(91)91226-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004962873"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02777718", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007953413", 
          "https://doi.org/10.1007/bf02777718"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0002-9343(86)90587-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011815978"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02049408", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014430939", 
          "https://doi.org/10.1007/bf02049408"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1007/bf02049408", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014430939"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1007/bf02049408", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014430939"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0143-4179(92)90123-e", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019035159"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1748-1716.1978.tb06264.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023365865"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-4899-0744-8_24", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023768665", 
          "https://doi.org/10.1007/978-1-4899-0744-8_24"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0016-5085(91)90595-c", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026685368"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0016-5085(90)90849-v", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028866144"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01540348", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031200803", 
          "https://doi.org/10.1007/bf01540348"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01540348", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031200803", 
          "https://doi.org/10.1007/bf01540348"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.79.13.4226", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033195247"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01537267", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038055489", 
          "https://doi.org/10.1007/bf01537267"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0196-9781(85)90142-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040298786"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01296290", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041413584", 
          "https://doi.org/10.1007/bf01296290"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0196-9781(90)90206-k", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044928299"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-0115(90)90122-d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046703751"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0162-3109(90)90021-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046967757"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0162-3109(90)90021-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046967757"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0889-1591(92)90057-u", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047316082"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1507/endocrine1927.53.9_1106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048369707"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1111/1523-1747.ep12874665", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049169410", 
          "https://doi.org/10.1111/1523-1747.ep12874665"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1440-1827.1994.tb01723.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049593471"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-77814-8_1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053350538", 
          "https://doi.org/10.1007/978-3-642-77814-8_1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.2457950", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062538432"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075952025", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076546633", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077338386", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077860835", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078794553", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078803752", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078940828", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079495709", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079538201", 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02774234", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1080659643", 
          "https://doi.org/10.1007/bf02774234"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081612682", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081619058", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081681400", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082464763", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082464764", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082465718", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082833208", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.qjmed.a066953", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083495673"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1996-08", 
    "datePublishedReg": "1996-08-01", 
    "description": "Regulatory neuropeptides are widely distributed in the gastrointestinal tract, where they play an important role in motility, secretion, and immune and inflammatory responses. In this study, the rectal mucosal content of somatostatin (SOM), substance P (SP), beta-endorphin (BE), and thyrotropin-releasing hormone (TRH) was measured by radioimmunoassay in 56 patients with ulcerative colitis (UC), 15 patients with Crohn's disease (CD), 15 patients with acute infectious colitis (AIC), and 11 controls, who showed no inflammation of the rectal mucosa, nor abnormal bowel movements. The content of immunoreactive (ir)-SOM was decreased in UC patients, especially in those with persistent disease activity, while the levels of ir-SP, BE, and TRH were increased in such patients. Some changes of ir-peptide levels were also observed in CD and AIC patients. The changes in neuropeptide levels were analyzed in relation to histological grades of inflammation in UC patients, grades 4-5 showing the most significant changes. The levels of ir-SOM, SP, BE, and TRH showed no significant change in chronic persistent UC when measured 6-12 months after the initial examination. In contrast, in patients with remitting intermittent UC, the levels of SP and BE decreased during remission. Abnormal intestinal neuropeptide content may be implicated in the continued mucosal immune and inflammatory responses that are manifested in patients with inflammatory bowel disease.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/bf02355052", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1009747", 
        "issn": [
          "0944-1174", 
          "1435-5922"
        ], 
        "name": "Journal of Gastroenterology", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "31"
      }
    ], 
    "name": "Abnormal neuropeptide concentration in rectal mucosa of patients with inflammatory bowel disease", 
    "pagination": "525-532", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "041020f553b0b8b0fbc9bc924ffecc175285a871fed69306a7ffee92b956b555"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "8844473"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9430794"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf02355052"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1000853070"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf02355052", 
      "https://app.dimensions.ai/details/publication/pub.1000853070"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:57", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000365_0000000365/records_71680_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007%2FBF02355052"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf02355052'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf02355052'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf02355052'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf02355052'


 

This table displays all metadata directly associated to this object as RDF triples.

328 TRIPLES      21 PREDICATES      88 URIs      33 LITERALS      21 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf02355052 schema:about N1a5001e1ea9e4fc3ad270a51a473180e
2 N29bcb1bf4b9141f4b10f5cb937873770
3 N3ac82bfc3bd04a5c96abdb7a210083cc
4 N6c6c7f8874a4460db4ce24181480bd10
5 N8c3653be22454095a41572c98e5a94c7
6 N95338d0bd4cd417b98ea78b5a3cffcdc
7 N9c9fc1e33af54723938cee93e0bf89fd
8 Na67d1b194f9345d2a738a006d8ae30a8
9 Nd2344a2714be481c97efae5c7e6538fd
10 Ne4dd38d50aaa4ed3a25f6ad9fa622a21
11 Nf01b77680cc946b5b05ecdd56a8b76b8
12 Nfdf91094910e4423aee2e59dfd30175b
13 anzsrc-for:11
14 anzsrc-for:1107
15 schema:author Nb2164366f04d411a99d35dca38e46c8a
16 schema:citation sg:pub.10.1007/978-1-4899-0744-8_24
17 sg:pub.10.1007/978-3-642-77814-8_1
18 sg:pub.10.1007/bf01296290
19 sg:pub.10.1007/bf01537267
20 sg:pub.10.1007/bf01540348
21 sg:pub.10.1007/bf02049408
22 sg:pub.10.1007/bf02552546
23 sg:pub.10.1007/bf02774234
24 sg:pub.10.1007/bf02777718
25 sg:pub.10.1111/1523-1747.ep12874665
26 https://app.dimensions.ai/details/publication/pub.1075952025
27 https://app.dimensions.ai/details/publication/pub.1076546633
28 https://app.dimensions.ai/details/publication/pub.1077338386
29 https://app.dimensions.ai/details/publication/pub.1077860835
30 https://app.dimensions.ai/details/publication/pub.1078794553
31 https://app.dimensions.ai/details/publication/pub.1078803752
32 https://app.dimensions.ai/details/publication/pub.1078940828
33 https://app.dimensions.ai/details/publication/pub.1079495709
34 https://app.dimensions.ai/details/publication/pub.1079538201
35 https://app.dimensions.ai/details/publication/pub.1081612682
36 https://app.dimensions.ai/details/publication/pub.1081619058
37 https://app.dimensions.ai/details/publication/pub.1081681400
38 https://app.dimensions.ai/details/publication/pub.1082464763
39 https://app.dimensions.ai/details/publication/pub.1082464764
40 https://app.dimensions.ai/details/publication/pub.1082465718
41 https://app.dimensions.ai/details/publication/pub.1082833208
42 https://doi.org/10.1007/bf02049408
43 https://doi.org/10.1007/bf02552546
44 https://doi.org/10.1016/0002-9343(86)90587-5
45 https://doi.org/10.1016/0006-291x(91)91226-3
46 https://doi.org/10.1016/0016-5085(90)90849-v
47 https://doi.org/10.1016/0016-5085(91)90595-c
48 https://doi.org/10.1016/0143-4179(92)90123-e
49 https://doi.org/10.1016/0162-3109(90)90021-6
50 https://doi.org/10.1016/0167-0115(90)90122-d
51 https://doi.org/10.1016/0167-0115(93)90040-f
52 https://doi.org/10.1016/0196-9781(85)90142-1
53 https://doi.org/10.1016/0196-9781(90)90206-k
54 https://doi.org/10.1016/0889-1591(92)90057-u
55 https://doi.org/10.1073/pnas.79.13.4226
56 https://doi.org/10.1093/oxfordjournals.qjmed.a066953
57 https://doi.org/10.1111/j.1440-1827.1994.tb01723.x
58 https://doi.org/10.1111/j.1748-1716.1978.tb06264.x
59 https://doi.org/10.1126/science.2457950
60 https://doi.org/10.1136/bmj.2.4947.1041
61 https://doi.org/10.1507/endocrine1927.53.9_1106
62 https://doi.org/10.1530/acta.0.0830225
63 schema:datePublished 1996-08
64 schema:datePublishedReg 1996-08-01
65 schema:description Regulatory neuropeptides are widely distributed in the gastrointestinal tract, where they play an important role in motility, secretion, and immune and inflammatory responses. In this study, the rectal mucosal content of somatostatin (SOM), substance P (SP), beta-endorphin (BE), and thyrotropin-releasing hormone (TRH) was measured by radioimmunoassay in 56 patients with ulcerative colitis (UC), 15 patients with Crohn's disease (CD), 15 patients with acute infectious colitis (AIC), and 11 controls, who showed no inflammation of the rectal mucosa, nor abnormal bowel movements. The content of immunoreactive (ir)-SOM was decreased in UC patients, especially in those with persistent disease activity, while the levels of ir-SP, BE, and TRH were increased in such patients. Some changes of ir-peptide levels were also observed in CD and AIC patients. The changes in neuropeptide levels were analyzed in relation to histological grades of inflammation in UC patients, grades 4-5 showing the most significant changes. The levels of ir-SOM, SP, BE, and TRH showed no significant change in chronic persistent UC when measured 6-12 months after the initial examination. In contrast, in patients with remitting intermittent UC, the levels of SP and BE decreased during remission. Abnormal intestinal neuropeptide content may be implicated in the continued mucosal immune and inflammatory responses that are manifested in patients with inflammatory bowel disease.
66 schema:genre research_article
67 schema:inLanguage en
68 schema:isAccessibleForFree false
69 schema:isPartOf N4cc81d50d943431393834cd205f26ecf
70 Nb80660d3a76f4cc487c6b55f178ceb15
71 sg:journal.1009747
72 schema:name Abnormal neuropeptide concentration in rectal mucosa of patients with inflammatory bowel disease
73 schema:pagination 525-532
74 schema:productId N1efc54f2a5bc4ba3b007f79592085b2b
75 N398a1286654b4ca786795a0dfc63a28f
76 N3f8bac3e5b60435f91fff153e5ba44ab
77 N70cbcd2339e0487286b016066184b11f
78 Ncc8bd6e3d2dd4f29868df3aaa0255bb9
79 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000853070
80 https://doi.org/10.1007/bf02355052
81 schema:sdDatePublished 2019-04-11T12:57
82 schema:sdLicense https://scigraph.springernature.com/explorer/license/
83 schema:sdPublisher Nee1afad9ab69430faca4b2833cbe98ed
84 schema:url http://link.springer.com/10.1007%2FBF02355052
85 sgo:license sg:explorer/license/
86 sgo:sdDataset articles
87 rdf:type schema:ScholarlyArticle
88 N0b6be529b29b42f2bccdc0d32f2ebd17 rdf:first sg:person.01225060647.95
89 rdf:rest N2f9f8917d21841668c48bac776b3c76c
90 N156145182ae3433ebbf7e0480c1e4303 rdf:first sg:person.01162701441.28
91 rdf:rest Na89ec39310be49f58ec149a87dbefe5d
92 N1a5001e1ea9e4fc3ad270a51a473180e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
93 schema:name Radioimmunoassay
94 rdf:type schema:DefinedTerm
95 N1efc54f2a5bc4ba3b007f79592085b2b schema:name doi
96 schema:value 10.1007/bf02355052
97 rdf:type schema:PropertyValue
98 N29bcb1bf4b9141f4b10f5cb937873770 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Humans
100 rdf:type schema:DefinedTerm
101 N2f9f8917d21841668c48bac776b3c76c rdf:first sg:person.01110442572.43
102 rdf:rest N5f5ff8395af54e46aeba4959203592b4
103 N398a1286654b4ca786795a0dfc63a28f schema:name nlm_unique_id
104 schema:value 9430794
105 rdf:type schema:PropertyValue
106 N3ac82bfc3bd04a5c96abdb7a210083cc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Biopsy
108 rdf:type schema:DefinedTerm
109 N3f8bac3e5b60435f91fff153e5ba44ab schema:name dimensions_id
110 schema:value pub.1000853070
111 rdf:type schema:PropertyValue
112 N4cc81d50d943431393834cd205f26ecf schema:volumeNumber 31
113 rdf:type schema:PublicationVolume
114 N58e00d895ca645dca7e4de096a7716b3 rdf:first sg:person.0631204540.45
115 rdf:rest N98bb75e0b6ad42ef89728a13c11f2900
116 N5f5ff8395af54e46aeba4959203592b4 rdf:first sg:person.012571543577.39
117 rdf:rest N58e00d895ca645dca7e4de096a7716b3
118 N6534209f682e4282ac3e73d339eb9614 rdf:first sg:person.01112026626.27
119 rdf:rest Nee14a1d440314191b074aff15de7f0c5
120 N6c6c7f8874a4460db4ce24181480bd10 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Colonoscopy
122 rdf:type schema:DefinedTerm
123 N70cbcd2339e0487286b016066184b11f schema:name readcube_id
124 schema:value 041020f553b0b8b0fbc9bc924ffecc175285a871fed69306a7ffee92b956b555
125 rdf:type schema:PropertyValue
126 N8c3653be22454095a41572c98e5a94c7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Intestinal Mucosa
128 rdf:type schema:DefinedTerm
129 N95338d0bd4cd417b98ea78b5a3cffcdc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Adult
131 rdf:type schema:DefinedTerm
132 N98bb75e0b6ad42ef89728a13c11f2900 rdf:first sg:person.01013546340.06
133 rdf:rest N6534209f682e4282ac3e73d339eb9614
134 N9c9fc1e33af54723938cee93e0bf89fd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Neuropeptides
136 rdf:type schema:DefinedTerm
137 Na67d1b194f9345d2a738a006d8ae30a8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Case-Control Studies
139 rdf:type schema:DefinedTerm
140 Na888b4fe8a1941a4b4453d0c2376d649 rdf:first sg:person.0607317206.74
141 rdf:rest N156145182ae3433ebbf7e0480c1e4303
142 Na89ec39310be49f58ec149a87dbefe5d rdf:first sg:person.01300651260.17
143 rdf:rest N0b6be529b29b42f2bccdc0d32f2ebd17
144 Nb2164366f04d411a99d35dca38e46c8a rdf:first sg:person.01173353312.53
145 rdf:rest Na888b4fe8a1941a4b4453d0c2376d649
146 Nb80660d3a76f4cc487c6b55f178ceb15 schema:issueNumber 4
147 rdf:type schema:PublicationIssue
148 Ncc8bd6e3d2dd4f29868df3aaa0255bb9 schema:name pubmed_id
149 schema:value 8844473
150 rdf:type schema:PropertyValue
151 Nd2344a2714be481c97efae5c7e6538fd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Inflammatory Bowel Diseases
153 rdf:type schema:DefinedTerm
154 Ne4dd38d50aaa4ed3a25f6ad9fa622a21 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Male
156 rdf:type schema:DefinedTerm
157 Nee14a1d440314191b074aff15de7f0c5 rdf:first sg:person.0723362470.15
158 rdf:rest rdf:nil
159 Nee1afad9ab69430faca4b2833cbe98ed schema:name Springer Nature - SN SciGraph project
160 rdf:type schema:Organization
161 Nf01b77680cc946b5b05ecdd56a8b76b8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Female
163 rdf:type schema:DefinedTerm
164 Nfdf91094910e4423aee2e59dfd30175b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Rectum
166 rdf:type schema:DefinedTerm
167 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
168 schema:name Medical and Health Sciences
169 rdf:type schema:DefinedTerm
170 anzsrc-for:1107 schema:inDefinedTermSet anzsrc-for:
171 schema:name Immunology
172 rdf:type schema:DefinedTerm
173 sg:journal.1009747 schema:issn 0944-1174
174 1435-5922
175 schema:name Journal of Gastroenterology
176 rdf:type schema:Periodical
177 sg:person.01013546340.06 schema:affiliation https://www.grid.ac/institutes/grid.411234.1
178 schema:familyName Nagai
179 schema:givenName Hirofumi
180 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01013546340.06
181 rdf:type schema:Person
182 sg:person.01110442572.43 schema:affiliation https://www.grid.ac/institutes/grid.27476.30
183 schema:familyName Nishio
184 schema:givenName Yuji
185 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01110442572.43
186 rdf:type schema:Person
187 sg:person.01112026626.27 schema:affiliation https://www.grid.ac/institutes/grid.411234.1
188 schema:familyName Mitsuma
189 schema:givenName Terunori
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01112026626.27
191 rdf:type schema:Person
192 sg:person.01162701441.28 schema:affiliation https://www.grid.ac/institutes/grid.27476.30
193 schema:familyName Kusugami
194 schema:givenName Kazuo
195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162701441.28
196 rdf:type schema:Person
197 sg:person.01173353312.53 schema:affiliation https://www.grid.ac/institutes/grid.27476.30
198 schema:familyName Yamamoto
199 schema:givenName Hitoshi
200 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01173353312.53
201 rdf:type schema:Person
202 sg:person.01225060647.95 schema:affiliation https://www.grid.ac/institutes/grid.27476.30
203 schema:familyName Konagaya
204 schema:givenName Toshihiro
205 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01225060647.95
206 rdf:type schema:Person
207 sg:person.012571543577.39 schema:affiliation https://www.grid.ac/institutes/grid.411234.1
208 schema:familyName Kaneko
209 schema:givenName Hiroshi
210 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012571543577.39
211 rdf:type schema:Person
212 sg:person.01300651260.17 schema:affiliation https://www.grid.ac/institutes/grid.27476.30
213 schema:familyName Furusawa
214 schema:givenName Atsushi
215 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01300651260.17
216 rdf:type schema:Person
217 sg:person.0607317206.74 schema:affiliation https://www.grid.ac/institutes/grid.27476.30
218 schema:familyName Morise
219 schema:givenName Kimitomo
220 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0607317206.74
221 rdf:type schema:Person
222 sg:person.0631204540.45 schema:affiliation https://www.grid.ac/institutes/grid.411234.1
223 schema:familyName Uchida
224 schema:givenName Kiyoshi
225 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631204540.45
226 rdf:type schema:Person
227 sg:person.0723362470.15 schema:affiliation https://www.grid.ac/institutes/grid.69566.3a
228 schema:familyName Nagura
229 schema:givenName Hiroshi
230 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0723362470.15
231 rdf:type schema:Person
232 sg:pub.10.1007/978-1-4899-0744-8_24 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023768665
233 https://doi.org/10.1007/978-1-4899-0744-8_24
234 rdf:type schema:CreativeWork
235 sg:pub.10.1007/978-3-642-77814-8_1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053350538
236 https://doi.org/10.1007/978-3-642-77814-8_1
237 rdf:type schema:CreativeWork
238 sg:pub.10.1007/bf01296290 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041413584
239 https://doi.org/10.1007/bf01296290
240 rdf:type schema:CreativeWork
241 sg:pub.10.1007/bf01537267 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038055489
242 https://doi.org/10.1007/bf01537267
243 rdf:type schema:CreativeWork
244 sg:pub.10.1007/bf01540348 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031200803
245 https://doi.org/10.1007/bf01540348
246 rdf:type schema:CreativeWork
247 sg:pub.10.1007/bf02049408 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014430939
248 https://doi.org/10.1007/bf02049408
249 rdf:type schema:CreativeWork
250 sg:pub.10.1007/bf02552546 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000883767
251 https://doi.org/10.1007/bf02552546
252 rdf:type schema:CreativeWork
253 sg:pub.10.1007/bf02774234 schema:sameAs https://app.dimensions.ai/details/publication/pub.1080659643
254 https://doi.org/10.1007/bf02774234
255 rdf:type schema:CreativeWork
256 sg:pub.10.1007/bf02777718 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007953413
257 https://doi.org/10.1007/bf02777718
258 rdf:type schema:CreativeWork
259 sg:pub.10.1111/1523-1747.ep12874665 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049169410
260 https://doi.org/10.1111/1523-1747.ep12874665
261 rdf:type schema:CreativeWork
262 https://app.dimensions.ai/details/publication/pub.1075952025 schema:CreativeWork
263 https://app.dimensions.ai/details/publication/pub.1076546633 schema:CreativeWork
264 https://app.dimensions.ai/details/publication/pub.1077338386 schema:CreativeWork
265 https://app.dimensions.ai/details/publication/pub.1077860835 schema:CreativeWork
266 https://app.dimensions.ai/details/publication/pub.1078794553 schema:CreativeWork
267 https://app.dimensions.ai/details/publication/pub.1078803752 schema:CreativeWork
268 https://app.dimensions.ai/details/publication/pub.1078940828 schema:CreativeWork
269 https://app.dimensions.ai/details/publication/pub.1079495709 schema:CreativeWork
270 https://app.dimensions.ai/details/publication/pub.1079538201 schema:CreativeWork
271 https://app.dimensions.ai/details/publication/pub.1081612682 schema:CreativeWork
272 https://app.dimensions.ai/details/publication/pub.1081619058 schema:CreativeWork
273 https://app.dimensions.ai/details/publication/pub.1081681400 schema:CreativeWork
274 https://app.dimensions.ai/details/publication/pub.1082464763 schema:CreativeWork
275 https://app.dimensions.ai/details/publication/pub.1082464764 schema:CreativeWork
276 https://app.dimensions.ai/details/publication/pub.1082465718 schema:CreativeWork
277 https://app.dimensions.ai/details/publication/pub.1082833208 schema:CreativeWork
278 https://doi.org/10.1007/bf02049408 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014430939
279 rdf:type schema:CreativeWork
280 https://doi.org/10.1007/bf02552546 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000883767
281 rdf:type schema:CreativeWork
282 https://doi.org/10.1016/0002-9343(86)90587-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011815978
283 rdf:type schema:CreativeWork
284 https://doi.org/10.1016/0006-291x(91)91226-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004962873
285 rdf:type schema:CreativeWork
286 https://doi.org/10.1016/0016-5085(90)90849-v schema:sameAs https://app.dimensions.ai/details/publication/pub.1028866144
287 rdf:type schema:CreativeWork
288 https://doi.org/10.1016/0016-5085(91)90595-c schema:sameAs https://app.dimensions.ai/details/publication/pub.1026685368
289 rdf:type schema:CreativeWork
290 https://doi.org/10.1016/0143-4179(92)90123-e schema:sameAs https://app.dimensions.ai/details/publication/pub.1019035159
291 rdf:type schema:CreativeWork
292 https://doi.org/10.1016/0162-3109(90)90021-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046967757
293 rdf:type schema:CreativeWork
294 https://doi.org/10.1016/0167-0115(90)90122-d schema:sameAs https://app.dimensions.ai/details/publication/pub.1046703751
295 rdf:type schema:CreativeWork
296 https://doi.org/10.1016/0167-0115(93)90040-f schema:sameAs https://app.dimensions.ai/details/publication/pub.1002850195
297 rdf:type schema:CreativeWork
298 https://doi.org/10.1016/0196-9781(85)90142-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040298786
299 rdf:type schema:CreativeWork
300 https://doi.org/10.1016/0196-9781(90)90206-k schema:sameAs https://app.dimensions.ai/details/publication/pub.1044928299
301 rdf:type schema:CreativeWork
302 https://doi.org/10.1016/0889-1591(92)90057-u schema:sameAs https://app.dimensions.ai/details/publication/pub.1047316082
303 rdf:type schema:CreativeWork
304 https://doi.org/10.1073/pnas.79.13.4226 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033195247
305 rdf:type schema:CreativeWork
306 https://doi.org/10.1093/oxfordjournals.qjmed.a066953 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083495673
307 rdf:type schema:CreativeWork
308 https://doi.org/10.1111/j.1440-1827.1994.tb01723.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1049593471
309 rdf:type schema:CreativeWork
310 https://doi.org/10.1111/j.1748-1716.1978.tb06264.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1023365865
311 rdf:type schema:CreativeWork
312 https://doi.org/10.1126/science.2457950 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062538432
313 rdf:type schema:CreativeWork
314 https://doi.org/10.1136/bmj.2.4947.1041 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004911330
315 rdf:type schema:CreativeWork
316 https://doi.org/10.1507/endocrine1927.53.9_1106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048369707
317 rdf:type schema:CreativeWork
318 https://doi.org/10.1530/acta.0.0830225 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003123947
319 rdf:type schema:CreativeWork
320 https://www.grid.ac/institutes/grid.27476.30 schema:alternateName Nagoya University
321 schema:name First Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsurumai-cho, Showa-ku, 466, Nagoya, Japan
322 rdf:type schema:Organization
323 https://www.grid.ac/institutes/grid.411234.1 schema:alternateName Aichi Medical University
324 schema:name Fourth Department of Internal Medicine, Aichi Medical University, 21 Yazako-karimata, Nagakute-cho, 480-11, Aichi, Japan
325 rdf:type schema:Organization
326 https://www.grid.ac/institutes/grid.69566.3a schema:alternateName Tohoku University
327 schema:name Department of Pathology, Tohoku University of Medicine, 2-1 Seiryo-machi, Aoba-ku, 980, Sendai, Japan
328 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...