Longterm meningeal involvement as the only clinical manifestation of low grade malignant non-Hodgkin's lymphoma View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1990-12

AUTHORS

J. J. Heimans, P. W. Wijermans, C. H. Polman, P. C. Huijgens, G. J. Ossenkoppele, G. J. van Kamp

ABSTRACT

We present the case of a 56-year old man who developed -at the age of 46-paraesthesia and numbness in the perianal region, the feet and lower legs accompanied by the presence of B-lymphocytes in the cerebrospinal fluid (CSF). Despite intensive work-up an explanation was not found until he developed hepato-splenomegaly ten years after the initial symptoms. Haematologic evaluation at that time disclosed a low-grade malignant B-cell lymphoma. Repeated CSF examination revealed 31 leukocytes/mm3, of which were mainly lymphocytes. These proved to be B-lymphocytes of monoclonal origin.These findings suggest that a leptomeningeal localisation of a low-grade malignant lymphoma had been present for ten years before systemic manifestation of the disease. More... »

PAGES

275-277

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02341158

DOI

http://dx.doi.org/10.1007/bf02341158

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1031336665

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2086741


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