Squamous-cell carcinoma developing within anal lichen planus View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1998-01

AUTHORS

Salvatore Fundarò, Andrea Spallanzani, Elio Ricchi, Alfonso Carriero, Stefano Perrone, Giulia Giusti, Alberto Giannetti, GianCarlo De Bernardinis

ABSTRACT

AIM: We present a case of squamous-cell carcinoma developing within perianal lichen planus. This is a chronic or recurrent cutaneous and/or mucosal dermatosis affecting less than 1 percent of the population. Neoplastic degeneration of cutaneous lichen planus is rare; only one case of squamous-cell carcinoma developing within perianal lichen planus has been described up until now in the international literature. CASE REPORT: Our case involved a 68-year-old woman with chronic, long-term lichen planus spreading all over the vulva and perianal region and the mucosa of the anal canal, where squamous-cell carcinoma developed within the perianal lichen planus. Treatment consisted of wide, circular excision of the perianal skin and mucosectomy of the anal canal up to as far as 1 cm above the dentate line. Reconstruction was performed by means of two V-Y bilateral subcutaneous flaps. CONCLUSION: Wide excision was performed not only to remove the squamous-cell carcinoma but also the lichen planus to prevent recurrence of metachronous or synchronous squamous-cell carcinoma. Follow-up at one year after surgery showed no local recurrence of either lichen planus or squamous-cell carcinoma, which suggests that surgical removal should be the therapy of choice for long-term, chronic perianal lichen planus that has proved to be resistant to medical therapy. More... »

PAGES

111-114

References to SciGraph publications

  • 1996-03. Vertical subcutaneous pedicle flaps for posterior perineal reconstruction in DISEASES OF THE COLON & RECTUM
  • 1990-09. Current status—Perianal and anal canal neoplasms in DISEASES OF THE COLON & RECTUM
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf02236905

    DOI

    http://dx.doi.org/10.1007/bf02236905

    DIMENSIONS

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    PUBMED

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