EEG development in early treated PKU patients from birth to 6 years of age View Full Text


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Article Info

DATE

1990-01

AUTHORS

J. Pietz, A. Lütcke, D. Sontheimer, Ch. Benninger, B. Pietz, U. Batzler, A. Heusser

ABSTRACT

In 126 early treated PKU patients (type I and type II) a close EEG follow up was performed from birth up to 6 years of age. A total of 1465 EEGs were performed before and after onset of dietary treatment and on 11 more subsequent occasions. The composition of the background activity was normal up to 6 years when only a small number of the children (19) showed no dominant alpha activity. The frequency of epileptiform activity of generalised as well as focal type was low in the first 2 years of life, but afterwards slightly enhanced in comparison to normal control groups. Other findings like generalised theta paroxysms or focal slow waves were rarely observed. Under a standardised protein load at 6 months (52 patients) and at 5 years of age (42 patients) a moderate generalised slowing of the background activity but no other abnormalities were noted. More... »

PAGES

28-33

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02126296

DOI

http://dx.doi.org/10.1007/bf02126296

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1007034329

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2091928


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