Evolution of alu family repeats since the divergence of human and chimpanzee View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1985-12

AUTHORS

Ikuhisa Sawada, Cary Willard, Che-Kun James Shen, Barbara Chapman, Allan C. Wilson, Carl W. Schmid

ABSTRACT

The DNA sequences of three members of the Alu family of repeated sequences located 5' to the chimpanzee alpha 2 gene have been determined. The base sequences of the three corresponding human Alu family repeats have been previously determined, permitting the comparison of identical Alu family members in human and chimpanzee. Here we compare the sequences of seven pairs of chimpanzee and human Alu repeats. In each case, with the exception of minor sequence differences, the identical Alu repeat is located at identical sites in the human and chimpanzee genomes. The Alu repeats diverge at the rate expected for nonselected sequences. Sequence conversion has not replaced any of these 14 Alu family members since the divergence between chimpanzee and human. More... »

PAGES

316-322

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02115687

DOI

http://dx.doi.org/10.1007/bf02115687

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1033052332

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/3003370


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52 schema:description The DNA sequences of three members of the Alu family of repeated sequences located 5' to the chimpanzee alpha 2 gene have been determined. The base sequences of the three corresponding human Alu family repeats have been previously determined, permitting the comparison of identical Alu family members in human and chimpanzee. Here we compare the sequences of seven pairs of chimpanzee and human Alu repeats. In each case, with the exception of minor sequence differences, the identical Alu repeat is located at identical sites in the human and chimpanzee genomes. The Alu repeats diverge at the rate expected for nonselected sequences. Sequence conversion has not replaced any of these 14 Alu family members since the divergence between chimpanzee and human.
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