URF13, a ligand-gated, pore-forming receptor for T-toxin in the inner membrane ofcms-T mitochondria View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1995-08

AUTHORS

David M. Rhoads, Charles S. Levings, James N. Siedow

ABSTRACT

URF13 is the product of a mitochondrial-encoded gene (T-urf13) found only in maize plants containing the Texas male-sterile cytoplasm (cms-T), and it is thought to be responsible for both cytoplasmic male sterility and the susceptibility of cms-T maize to the fungal pathogens Bipolaris maydis race T and Phyllosticata maydis. Mitochondria isolated from cms-T maize are uniquely sensitive to pathotoxins (T-toxin) produced by these fungi and to methomyl (a commercial insecticide). URF13 acts as a receptor that specifically binds T-toxin to produce hydrophilic pores in the inner mitochondrial membrane. When expressed in Escherichia coli cells, URF13 also forms hydrophilic pores in the plasma membrane if exposed to T-toxin or methomyl. Topological studies established that URF13 contains three membrane-spanning alpha-helices, two of which are amphipathic and can contribute to pore formation. Chemical cross-linking of URF13 was used to demonstrate the existence of URF13 oligomers in cms-T mitochondria and E. coli cells. The ability of the carboxylate-specific reagent, N,N'-dicyclohexycarbodiimide, to cross-link URF13 was used in conjunction with site-directed mutagenesis to establish that the URF13 tetramer has a central core consisting of a four-alpha-helical bundle which undergoes a conformational change after interaction with T-toxin or methomyl. Overall, the experimental evidence indicates that URF13 functions as a ligand-gated, pore-forming T-toxin receptor in cms-T mitochondria. More... »

PAGES

437-445

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02110006

DOI

http://dx.doi.org/10.1007/bf02110006

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1033969336

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8595979


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amino Acid Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA, Mitochondrial", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genes, Plant", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Intracellular Membranes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mitochondria", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mitochondrial Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Models, Structural", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Sequence Data", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mycotoxins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Plant Diseases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Plant Leaves", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Plant Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Structure, Secondary", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Reproduction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Zea mays", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "Department of Botany/Developmental, Cell, and Molecular Biology Group, Duke University, Box 91000, 27708-1000, Durham, North Carolina", 
            "Department of Genetics, North Carolina State University, Box 7614, 27695-7614, Raleigh, North Carolina"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rhoads", 
        "givenName": "David M.", 
        "id": "sg:person.0647137671.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0647137671.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Genetics, North Carolina State University, Box 7614, 27695-7614, Raleigh, North Carolina"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Levings", 
        "givenName": "Charles S.", 
        "id": "sg:person.01311124414.79", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01311124414.79"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Department of Botany/Developmental, Cell, and Molecular Biology Group, Duke University, Box 91000, 27708-1000, Durham, North Carolina"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Siedow", 
        "givenName": "James N.", 
        "id": "sg:person.01261362460.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01261362460.04"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/0045-2068(79)90064-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000778925"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1104/pp.84.3.670", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001573241"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1104/pp.91.4.1296", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002099086"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.88.23.10865", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002287856"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0031-9422(00)84675-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007720094"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00015611", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008912278", 
          "https://doi.org/10.1007/bf00015611"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00015611", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008912278", 
          "https://doi.org/10.1007/bf00015611"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.86.12.4435", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010376726"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0031-9422(00)81726-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014293482"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.75.8.3841", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014446427"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00332225", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015724310", 
          "https://doi.org/10.1007/bf00332225"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0065-2660(08)60046-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016688828"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1104/pp.75.1.235", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017186729"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.77.1.418", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018974691"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0040-4039(00)94279-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019180535"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.91.17.8253", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022456568"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0045-2068(81)90024-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023560671"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1104/pp.76.2.508", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024909415"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1105/tpc.2.2.153", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026660922"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0968-0004(91)90090-i", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035016476"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1104/pp.63.6.1149", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035844768"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00315793", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036223341", 
          "https://doi.org/10.1007/bf00315793"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00315793", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036223341", 
          "https://doi.org/10.1007/bf00315793"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0040-4039(00)92768-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037104489"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.92.4.1167", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037901636"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.90.8.3388", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038104457"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.py.10.090172.000345", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040412257"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1104/pp.59.4.540", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040488801"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00277764", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042316258", 
          "https://doi.org/10.1007/bf00277764"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00277764", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042316258", 
          "https://doi.org/10.1007/bf00277764"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1105/tpc.6.3.439", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043552836"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.74.11.5113", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044383007"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0076-6879(86)25009-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044404830"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1104/pp.77.4.912", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045544738"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00327189", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046136307", 
          "https://doi.org/10.1007/bf00327189"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(86)90465-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049113268"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.84.15.5374", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050811178"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.py.27.090189.002411", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053176690"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.90.13.5934", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053682309"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jxb/36.3.511", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059855910"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1094/phyto-62-968", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060103599"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1104/pp.105.3.775", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060840388"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.173.3991.67", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062503059"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.250.4983.942", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062541052"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.3276005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062603628"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2134/agronj1952.00021962004400010004x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068983705"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2135/cropsci1973.0011183x001300060028x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069016368"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2135/cropsci1983.0011183x002300030033x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069019693"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2307/3868927", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070467030"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2307/3869763", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070467737"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/j.1460-2075.1987.tb02398.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077183924"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/j.1460-2075.1990.tb08116.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078629385"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078635137", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082811459", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.aob.a086145", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083601408"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jhered.a108817", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083619487"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/j.1537-2197.1979.tb06206.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1100736072"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1995-08", 
    "datePublishedReg": "1995-08-01", 
    "description": "URF13 is the product of a mitochondrial-encoded gene (T-urf13) found only in maize plants containing the Texas male-sterile cytoplasm (cms-T), and it is thought to be responsible for both cytoplasmic male sterility and the susceptibility of cms-T maize to the fungal pathogens Bipolaris maydis race T and Phyllosticata maydis. Mitochondria isolated from cms-T maize are uniquely sensitive to pathotoxins (T-toxin) produced by these fungi and to methomyl (a commercial insecticide). URF13 acts as a receptor that specifically binds T-toxin to produce hydrophilic pores in the inner mitochondrial membrane. When expressed in Escherichia coli cells, URF13 also forms hydrophilic pores in the plasma membrane if exposed to T-toxin or methomyl. Topological studies established that URF13 contains three membrane-spanning alpha-helices, two of which are amphipathic and can contribute to pore formation. Chemical cross-linking of URF13 was used to demonstrate the existence of URF13 oligomers in cms-T mitochondria and E. coli cells. The ability of the carboxylate-specific reagent, N,N'-dicyclohexycarbodiimide, to cross-link URF13 was used in conjunction with site-directed mutagenesis to establish that the URF13 tetramer has a central core consisting of a four-alpha-helical bundle which undergoes a conformational change after interaction with T-toxin or methomyl. Overall, the experimental evidence indicates that URF13 functions as a ligand-gated, pore-forming T-toxin receptor in cms-T mitochondria.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/bf02110006", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1055350", 
        "issn": [
          "0145-479X", 
          "1573-6881"
        ], 
        "name": "Journal of Bioenergetics and Biomembranes", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "27"
      }
    ], 
    "name": "URF13, a ligand-gated, pore-forming receptor for T-toxin in the inner membrane ofcms-T mitochondria", 
    "pagination": "437-445", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "a1d25c351661a016cf54b5e94a9f9e787bc7eef8a70c8a31354e1acc539b315c"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "8595979"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "7701859"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf02110006"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1033969336"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf02110006", 
      "https://app.dimensions.ai/details/publication/pub.1033969336"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:06", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000360_0000000360/records_118335_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/BF02110006"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf02110006'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf02110006'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf02110006'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf02110006'


 

This table displays all metadata directly associated to this object as RDF triples.

312 TRIPLES      21 PREDICATES      98 URIs      36 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf02110006 schema:about N107be47b18a143e1a5ac3a608f205ac0
2 N10c6c95e49a9431da828957ac713d22e
3 N240b15a6cb34407387f254a10d5bcd26
4 N4aa2e107b580487d8bcfe60f7aef2444
5 N8e91ee03263544bf94dd94cc7cc33d65
6 N989a50192b0b42e6b773f92271e94ca9
7 Na6e6854f65974c1f8979517853c9e6fc
8 Nb198e36e7ed448c4bcae3560faf56c8d
9 Nb42b498b53424ea7803d43922be35451
10 Nb6f1748ff2d54c16893c530c5dbe392d
11 Nb8c2f25f68104d2283cd977b60ea8479
12 Nc52563b1c8674458a4ae39089e3c8382
13 Nc95ebb90928b4acf81e985eabbf6bb42
14 Nccb2ddb7e6d24bc483c4189e4ff93f6f
15 Ndeb24726954847d199ce8d530c43e261
16 anzsrc-for:06
17 anzsrc-for:0601
18 schema:author N18cb515aa05a41b4a5615f6c8cfd4a18
19 schema:citation sg:pub.10.1007/bf00015611
20 sg:pub.10.1007/bf00277764
21 sg:pub.10.1007/bf00315793
22 sg:pub.10.1007/bf00327189
23 sg:pub.10.1007/bf00332225
24 https://app.dimensions.ai/details/publication/pub.1078635137
25 https://app.dimensions.ai/details/publication/pub.1082811459
26 https://doi.org/10.1002/j.1460-2075.1987.tb02398.x
27 https://doi.org/10.1002/j.1460-2075.1990.tb08116.x
28 https://doi.org/10.1002/j.1537-2197.1979.tb06206.x
29 https://doi.org/10.1016/0045-2068(79)90064-6
30 https://doi.org/10.1016/0045-2068(81)90024-9
31 https://doi.org/10.1016/0092-8674(86)90465-4
32 https://doi.org/10.1016/0968-0004(91)90090-i
33 https://doi.org/10.1016/s0031-9422(00)81726-4
34 https://doi.org/10.1016/s0031-9422(00)84675-0
35 https://doi.org/10.1016/s0040-4039(00)92768-0
36 https://doi.org/10.1016/s0040-4039(00)94279-5
37 https://doi.org/10.1016/s0065-2660(08)60046-2
38 https://doi.org/10.1016/s0076-6879(86)25009-0
39 https://doi.org/10.1073/pnas.74.11.5113
40 https://doi.org/10.1073/pnas.75.8.3841
41 https://doi.org/10.1073/pnas.77.1.418
42 https://doi.org/10.1073/pnas.84.15.5374
43 https://doi.org/10.1073/pnas.86.12.4435
44 https://doi.org/10.1073/pnas.88.23.10865
45 https://doi.org/10.1073/pnas.90.13.5934
46 https://doi.org/10.1073/pnas.90.8.3388
47 https://doi.org/10.1073/pnas.91.17.8253
48 https://doi.org/10.1073/pnas.92.4.1167
49 https://doi.org/10.1093/jxb/36.3.511
50 https://doi.org/10.1093/oxfordjournals.aob.a086145
51 https://doi.org/10.1093/oxfordjournals.jhered.a108817
52 https://doi.org/10.1094/phyto-62-968
53 https://doi.org/10.1104/pp.105.3.775
54 https://doi.org/10.1104/pp.59.4.540
55 https://doi.org/10.1104/pp.63.6.1149
56 https://doi.org/10.1104/pp.75.1.235
57 https://doi.org/10.1104/pp.76.2.508
58 https://doi.org/10.1104/pp.77.4.912
59 https://doi.org/10.1104/pp.84.3.670
60 https://doi.org/10.1104/pp.91.4.1296
61 https://doi.org/10.1105/tpc.2.2.153
62 https://doi.org/10.1105/tpc.6.3.439
63 https://doi.org/10.1126/science.173.3991.67
64 https://doi.org/10.1126/science.250.4983.942
65 https://doi.org/10.1126/science.3276005
66 https://doi.org/10.1146/annurev.py.10.090172.000345
67 https://doi.org/10.1146/annurev.py.27.090189.002411
68 https://doi.org/10.2134/agronj1952.00021962004400010004x
69 https://doi.org/10.2135/cropsci1973.0011183x001300060028x
70 https://doi.org/10.2135/cropsci1983.0011183x002300030033x
71 https://doi.org/10.2307/3868927
72 https://doi.org/10.2307/3869763
73 schema:datePublished 1995-08
74 schema:datePublishedReg 1995-08-01
75 schema:description URF13 is the product of a mitochondrial-encoded gene (T-urf13) found only in maize plants containing the Texas male-sterile cytoplasm (cms-T), and it is thought to be responsible for both cytoplasmic male sterility and the susceptibility of cms-T maize to the fungal pathogens Bipolaris maydis race T and Phyllosticata maydis. Mitochondria isolated from cms-T maize are uniquely sensitive to pathotoxins (T-toxin) produced by these fungi and to methomyl (a commercial insecticide). URF13 acts as a receptor that specifically binds T-toxin to produce hydrophilic pores in the inner mitochondrial membrane. When expressed in Escherichia coli cells, URF13 also forms hydrophilic pores in the plasma membrane if exposed to T-toxin or methomyl. Topological studies established that URF13 contains three membrane-spanning alpha-helices, two of which are amphipathic and can contribute to pore formation. Chemical cross-linking of URF13 was used to demonstrate the existence of URF13 oligomers in cms-T mitochondria and E. coli cells. The ability of the carboxylate-specific reagent, N,N'-dicyclohexycarbodiimide, to cross-link URF13 was used in conjunction with site-directed mutagenesis to establish that the URF13 tetramer has a central core consisting of a four-alpha-helical bundle which undergoes a conformational change after interaction with T-toxin or methomyl. Overall, the experimental evidence indicates that URF13 functions as a ligand-gated, pore-forming T-toxin receptor in cms-T mitochondria.
76 schema:genre research_article
77 schema:inLanguage en
78 schema:isAccessibleForFree false
79 schema:isPartOf N453bab87608f4451b86619e08ef49b30
80 N74c7a783add549e592bca862d68e01b7
81 sg:journal.1055350
82 schema:name URF13, a ligand-gated, pore-forming receptor for T-toxin in the inner membrane ofcms-T mitochondria
83 schema:pagination 437-445
84 schema:productId N3afb2b41e6b14ba9880c2e00b1c9a2c2
85 N50e70d475e204795943e6cce11432716
86 Nd20ccc2693514448872d8e8ded644013
87 Ne8182140c508471bbe4cdb945967b552
88 Nfc3e5b8201684e46923db7c5b3ccdd60
89 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033969336
90 https://doi.org/10.1007/bf02110006
91 schema:sdDatePublished 2019-04-11T12:06
92 schema:sdLicense https://scigraph.springernature.com/explorer/license/
93 schema:sdPublisher Nee202281f2a948edb2118b9e782cc2da
94 schema:url http://link.springer.com/10.1007/BF02110006
95 sgo:license sg:explorer/license/
96 sgo:sdDataset articles
97 rdf:type schema:ScholarlyArticle
98 N107be47b18a143e1a5ac3a608f205ac0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Molecular Sequence Data
100 rdf:type schema:DefinedTerm
101 N10c6c95e49a9431da828957ac713d22e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Plant Proteins
103 rdf:type schema:DefinedTerm
104 N18cb515aa05a41b4a5615f6c8cfd4a18 rdf:first sg:person.0647137671.23
105 rdf:rest Nc156289a281d4074bcf3aaa99dbabcbc
106 N1fa6ed3faf0a4f87ba7397c9f4e274ef schema:name Department of Botany/Developmental, Cell, and Molecular Biology Group, Duke University, Box 91000, 27708-1000, Durham, North Carolina
107 rdf:type schema:Organization
108 N240b15a6cb34407387f254a10d5bcd26 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Amino Acid Sequence
110 rdf:type schema:DefinedTerm
111 N3afb2b41e6b14ba9880c2e00b1c9a2c2 schema:name dimensions_id
112 schema:value pub.1033969336
113 rdf:type schema:PropertyValue
114 N453bab87608f4451b86619e08ef49b30 schema:issueNumber 4
115 rdf:type schema:PublicationIssue
116 N4aa2e107b580487d8bcfe60f7aef2444 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Models, Structural
118 rdf:type schema:DefinedTerm
119 N50e70d475e204795943e6cce11432716 schema:name pubmed_id
120 schema:value 8595979
121 rdf:type schema:PropertyValue
122 N74c7a783add549e592bca862d68e01b7 schema:volumeNumber 27
123 rdf:type schema:PublicationVolume
124 N8e91ee03263544bf94dd94cc7cc33d65 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Reproduction
126 rdf:type schema:DefinedTerm
127 N97103bcfefda4fa6acb7e6c3d5a1a811 rdf:first sg:person.01261362460.04
128 rdf:rest rdf:nil
129 N989a50192b0b42e6b773f92271e94ca9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Mitochondrial Proteins
131 rdf:type schema:DefinedTerm
132 Na6e6854f65974c1f8979517853c9e6fc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Genes, Plant
134 rdf:type schema:DefinedTerm
135 Nb198e36e7ed448c4bcae3560faf56c8d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Mitochondria
137 rdf:type schema:DefinedTerm
138 Nb42b498b53424ea7803d43922be35451 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Mycotoxins
140 rdf:type schema:DefinedTerm
141 Nb6f1748ff2d54c16893c530c5dbe392d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name DNA, Mitochondrial
143 rdf:type schema:DefinedTerm
144 Nb8c2f25f68104d2283cd977b60ea8479 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Plant Diseases
146 rdf:type schema:DefinedTerm
147 Nc156289a281d4074bcf3aaa99dbabcbc rdf:first sg:person.01311124414.79
148 rdf:rest N97103bcfefda4fa6acb7e6c3d5a1a811
149 Nc52563b1c8674458a4ae39089e3c8382 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Intracellular Membranes
151 rdf:type schema:DefinedTerm
152 Nc95ebb90928b4acf81e985eabbf6bb42 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Plant Leaves
154 rdf:type schema:DefinedTerm
155 Nccb2ddb7e6d24bc483c4189e4ff93f6f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Protein Structure, Secondary
157 rdf:type schema:DefinedTerm
158 Nd20ccc2693514448872d8e8ded644013 schema:name nlm_unique_id
159 schema:value 7701859
160 rdf:type schema:PropertyValue
161 Ndeb24726954847d199ce8d530c43e261 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Zea mays
163 rdf:type schema:DefinedTerm
164 Ne7a3c42c064542d6a36b27e4357f6778 schema:name Department of Genetics, North Carolina State University, Box 7614, 27695-7614, Raleigh, North Carolina
165 rdf:type schema:Organization
166 Ne8182140c508471bbe4cdb945967b552 schema:name doi
167 schema:value 10.1007/bf02110006
168 rdf:type schema:PropertyValue
169 Ne98c5996e9e9450ab0c1e5751e30f12f schema:name Department of Botany/Developmental, Cell, and Molecular Biology Group, Duke University, Box 91000, 27708-1000, Durham, North Carolina
170 Department of Genetics, North Carolina State University, Box 7614, 27695-7614, Raleigh, North Carolina
171 rdf:type schema:Organization
172 Nee202281f2a948edb2118b9e782cc2da schema:name Springer Nature - SN SciGraph project
173 rdf:type schema:Organization
174 Nfc3e5b8201684e46923db7c5b3ccdd60 schema:name readcube_id
175 schema:value a1d25c351661a016cf54b5e94a9f9e787bc7eef8a70c8a31354e1acc539b315c
176 rdf:type schema:PropertyValue
177 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
178 schema:name Biological Sciences
179 rdf:type schema:DefinedTerm
180 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
181 schema:name Biochemistry and Cell Biology
182 rdf:type schema:DefinedTerm
183 sg:journal.1055350 schema:issn 0145-479X
184 1573-6881
185 schema:name Journal of Bioenergetics and Biomembranes
186 rdf:type schema:Periodical
187 sg:person.01261362460.04 schema:affiliation N1fa6ed3faf0a4f87ba7397c9f4e274ef
188 schema:familyName Siedow
189 schema:givenName James N.
190 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01261362460.04
191 rdf:type schema:Person
192 sg:person.01311124414.79 schema:affiliation Ne7a3c42c064542d6a36b27e4357f6778
193 schema:familyName Levings
194 schema:givenName Charles S.
195 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01311124414.79
196 rdf:type schema:Person
197 sg:person.0647137671.23 schema:affiliation Ne98c5996e9e9450ab0c1e5751e30f12f
198 schema:familyName Rhoads
199 schema:givenName David M.
200 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0647137671.23
201 rdf:type schema:Person
202 sg:pub.10.1007/bf00015611 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008912278
203 https://doi.org/10.1007/bf00015611
204 rdf:type schema:CreativeWork
205 sg:pub.10.1007/bf00277764 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042316258
206 https://doi.org/10.1007/bf00277764
207 rdf:type schema:CreativeWork
208 sg:pub.10.1007/bf00315793 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036223341
209 https://doi.org/10.1007/bf00315793
210 rdf:type schema:CreativeWork
211 sg:pub.10.1007/bf00327189 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046136307
212 https://doi.org/10.1007/bf00327189
213 rdf:type schema:CreativeWork
214 sg:pub.10.1007/bf00332225 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015724310
215 https://doi.org/10.1007/bf00332225
216 rdf:type schema:CreativeWork
217 https://app.dimensions.ai/details/publication/pub.1078635137 schema:CreativeWork
218 https://app.dimensions.ai/details/publication/pub.1082811459 schema:CreativeWork
219 https://doi.org/10.1002/j.1460-2075.1987.tb02398.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1077183924
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1002/j.1460-2075.1990.tb08116.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1078629385
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1002/j.1537-2197.1979.tb06206.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1100736072
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1016/0045-2068(79)90064-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000778925
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1016/0045-2068(81)90024-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023560671
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1016/0092-8674(86)90465-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049113268
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1016/0968-0004(91)90090-i schema:sameAs https://app.dimensions.ai/details/publication/pub.1035016476
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1016/s0031-9422(00)81726-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014293482
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1016/s0031-9422(00)84675-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007720094
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1016/s0040-4039(00)92768-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037104489
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1016/s0040-4039(00)94279-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019180535
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1016/s0065-2660(08)60046-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016688828
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1016/s0076-6879(86)25009-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044404830
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1073/pnas.74.11.5113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044383007
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1073/pnas.75.8.3841 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014446427
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1073/pnas.77.1.418 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018974691
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1073/pnas.84.15.5374 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050811178
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1073/pnas.86.12.4435 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010376726
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1073/pnas.88.23.10865 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002287856
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1073/pnas.90.13.5934 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053682309
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1073/pnas.90.8.3388 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038104457
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1073/pnas.91.17.8253 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022456568
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1073/pnas.92.4.1167 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037901636
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1093/jxb/36.3.511 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059855910
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1093/oxfordjournals.aob.a086145 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083601408
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1093/oxfordjournals.jhered.a108817 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083619487
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1094/phyto-62-968 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060103599
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1104/pp.105.3.775 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060840388
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1104/pp.59.4.540 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040488801
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1104/pp.63.6.1149 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035844768
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1104/pp.75.1.235 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017186729
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1104/pp.76.2.508 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024909415
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1104/pp.77.4.912 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045544738
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1104/pp.84.3.670 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001573241
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1104/pp.91.4.1296 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002099086
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1105/tpc.2.2.153 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026660922
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1105/tpc.6.3.439 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043552836
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1126/science.173.3991.67 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062503059
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1126/science.250.4983.942 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062541052
296 rdf:type schema:CreativeWork
297 https://doi.org/10.1126/science.3276005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062603628
298 rdf:type schema:CreativeWork
299 https://doi.org/10.1146/annurev.py.10.090172.000345 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040412257
300 rdf:type schema:CreativeWork
301 https://doi.org/10.1146/annurev.py.27.090189.002411 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053176690
302 rdf:type schema:CreativeWork
303 https://doi.org/10.2134/agronj1952.00021962004400010004x schema:sameAs https://app.dimensions.ai/details/publication/pub.1068983705
304 rdf:type schema:CreativeWork
305 https://doi.org/10.2135/cropsci1973.0011183x001300060028x schema:sameAs https://app.dimensions.ai/details/publication/pub.1069016368
306 rdf:type schema:CreativeWork
307 https://doi.org/10.2135/cropsci1983.0011183x002300030033x schema:sameAs https://app.dimensions.ai/details/publication/pub.1069019693
308 rdf:type schema:CreativeWork
309 https://doi.org/10.2307/3868927 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070467030
310 rdf:type schema:CreativeWork
311 https://doi.org/10.2307/3869763 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070467737
312 rdf:type schema:CreativeWork
 




Preview window. Press ESC to close (or click here)


...