Acute colorectal ischemia after aortic surgery: Pathophysiology and prognostic criteria View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1992-03

AUTHORS

Jean-Christophe Farkas, Nadine Calvo-Verjat, Claude Laurian, Jean Marzelle, Jean-Marc Fichelle, Fréderic Gigou, Jean-Pierre Blériot, François Dazza, Jean Carlet, Jean-Michel Cormier

ABSTRACT

Acute colorectal ischemia is a rare though potentially lethal complication of aortic surgery. We reviewed our recent experience with 16 cases in order to analyze its causative and prognostic factors. The incidence was 2.8%, and the inferior mesenteric artery was occluded in all cases. All patients also had severe occlusive disease of at least two of the hypogastric or deep femoral arteries. Hypoperfusion due to arterial ligation, prosthetic occlusion or embolism was responsible in half the cases. Ischemia and perfusion due to aortic cross-clamping or perioperative hemorrhage were involved in the rest of the cases. Postoperative mortality was 31%. The mortality was lower for partial, nontransmural necrosis, and for elective operations. Recurrent intestinal ischemia, transmural necrosis, surgery for ruptured aneurysm, intestinal hemorrhage and pulmonary edema were associated with a higher mortality rate. All patients with anuria or extrarenal epuration and hepatic cytolysis died. Although reconstruction of the inferior mesenteric artery might lessen the incidence of postoperative colonic ischemia due to hypoperfusion, the role of oxygen free radicals should be investigated in humans, in order to afford colonic protection against the consequences of ischemia-reperfusion. More... »

PAGES

111-118

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02042730

DOI

http://dx.doi.org/10.1007/bf02042730

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1031141893

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/1599829


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70 intestinal ischemia
71 ischemia
72 lethal complication
73 ligation
74 mesenteric artery
75 mortality
76 mortality rate
77 necrosis
78 nontransmural necrosis
79 occlusion
80 occlusive disease
81 operation
82 order
83 oxygen free radicals
84 pathophysiology
85 patients
86 perfusion
87 perioperative hemorrhage
88 postoperative colonic ischemia
89 postoperative mortality
90 prognostic criteria
91 prognostic factors
92 prosthetic occlusion
93 protection
94 pulmonary edema
95 radicals
96 rate
97 recent experience
98 reconstruction
99 rest
100 role
101 severe occlusive disease
102 surgery
103 transmural necrosis
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