Acute colorectal ischemia after aortic surgery: Pathophysiology and prognostic criteria View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1992-03

AUTHORS

Jean-Christophe Farkas, Nadine Calvo-Verjat, Claude Laurian, Jean Marzelle, Jean-Marc Fichelle, Fréderic Gigou, Jean-Pierre Blériot, François Dazza, Jean Carlet, Jean-Michel Cormier

ABSTRACT

Acute colorectal ischemia is a rare though potentially lethal complication of aortic surgery. We reviewed our recent experience with 16 cases in order to analyze its causative and prognostic factors. The incidence was 2.8%, and the inferior mesenteric artery was occluded in all cases. All patients also had severe occlusive disease of at least two of the hypogastric or deep femoral arteries. Hypoperfusion due to arterial ligation, prosthetic occlusion or embolism was responsible in half the cases. Ischemia and perfusion due to aortic cross-clamping or perioperative hemorrhage were involved in the rest of the cases. Postoperative mortality was 31%. The mortality was lower for partial, nontransmural necrosis, and for elective operations. Recurrent intestinal ischemia, transmural necrosis, surgery for ruptured aneurysm, intestinal hemorrhage and pulmonary edema were associated with a higher mortality rate. All patients with anuria or extrarenal epuration and hepatic cytolysis died. Although reconstruction of the inferior mesenteric artery might lessen the incidence of postoperative colonic ischemia due to hypoperfusion, the role of oxygen free radicals should be investigated in humans, in order to afford colonic protection against the consequences of ischemia-reperfusion. More... »

PAGES

111-118

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02042730

DOI

http://dx.doi.org/10.1007/bf02042730

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1031141893

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/1599829


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72 mesenteric artery
73 mortality
74 mortality rate
75 necrosis
76 nontransmural necrosis
77 occlusion
78 occlusive disease
79 operation
80 order
81 oxygen free radicals
82 pathophysiology
83 patients
84 perfusion
85 perioperative hemorrhage
86 postoperative colonic ischemia
87 postoperative mortality
88 prognostic criteria
89 prognostic factors
90 prosthetic occlusion
91 protection
92 pulmonary edema
93 radicals
94 rate
95 recent experience
96 reconstruction
97 rest
98 role
99 severe occlusive disease
100 surgery
101 transmural necrosis
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