Growth hormone: the effect on skeletal renewal in the adult dog I. Morphometric studies View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1972-12

AUTHORS

W. H. Harris, R. P. Heaney, J. Jowsey, J. Cockin, C. Akins, J. Graham, E. H. Weinberg

ABSTRACT

In intact adult dogs of both sexes exogenous growth hormone induced a marked increase in new bone formation. The net effect on resorption could not be defined quantitatively but endosteal resorption was decreased. Intracortical resorption was increased but intracortical porosity rose only slightly. In addition to the decrease in endosteal resorption, there was abundant endosteal new bone formation. This rise in endosteal new bone formation plus the marked stimulus to periosteal new bone formation led to anet increase in skeletal mass. The bone formed was normal histologically and microradiographically. Despite a marked rise in new bone formation, alkaline phosphatase values remained unchanged. More... »

PAGES

1-13

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02012530

DOI

http://dx.doi.org/10.1007/bf02012530

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1015521891

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/4626613


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