Synthetic hydroxyapatite crystals View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1967-12

AUTHORS

W. F. Neuman, B. J. Mulryan

ABSTRACT

Synthetic hydroxyapatite crystals were produced under approximately physiological conditions both in the absence and presence of 0.025 M HCO3−.X-ray diffraction studies and solubility data established that the crystals formed from the bicarbonate medium were essentially a single phase, carbonate-apatite. These crystals were extremely minute, of composition comparable to bone mineral, and, on aging, showed very little increase in “crystallinity” in comparison with CO2-free preparations.Exchange studies with C14O2 established that about 60% of the CO2, presumably as CO3=, residedwithin the crystal lattice and 40%, presumably as HCO3−, resided in the hydration shells of the crystals. Of the latter, approximately 50% was lost on drying.Preliminary experiments with bones of young rats labelled with C14O2in vivo suggested that the model experiments are biologically applicable. Approximately 47% of the C14O2 in the bones was lost on drying. More... »

PAGES

94-104

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf02008079

DOI

http://dx.doi.org/10.1007/bf02008079

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1031254314

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6060154


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