Failure of teicoplanin therapy in two neutropenic patients with staphylococcal septicemia who recovered after administration of vancomycin View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1990-02

AUTHORS

F. Brunet, G. Vedel, F. Dreyfus, J. F. Vaxelaire, T. Giraud, B. Schremmer, J. F. Monsallier

ABSTRACT

A report is given on two neutropenic patients with staphylococcal septicemia caused byStaphylococcus haemolyticus andStaphylococcus aureus (both strains methicillin-resistant) who failed to respond to therapy with teicoplanin. Both strains were resistant to teicoplanin (MIC 16 and 8 mg/l respectively), but remained sensitive to vancomycin (MIC 2 and 4 mg/l respectively). Replacement of teicoplanin with vancomycin led to full recovery of both patients and their discharge from hospital. These two cases emphasize the importance of clinical and microbiological monitoring of patients with staphylococcal septicemia, even when glycopeptides are used for treatment. More... »

PAGES

145-147

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf01963643

DOI

http://dx.doi.org/10.1007/bf01963643

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1013317074

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2138543


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